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The two faces of pannexins: new roles in inflammation and repair

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Academic year: 2020

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Figure

Figure 1 Connexins and pannexins.Notes: (A, B) Connexin and pannexin share a similar structure, despite the absence of sequence homology
Figure 2 The two signaling arms of the inflammasome-activation cascade.of mature IL1Abbreviation:receptors (NLR)
Figure 3  and P2X channels and substantial movement of ATP and ions along their concentration gradients.Abbreviations:7P2X activity
Figure 4 Persistent Panx1 and P2X activation (A) leads to inflammasome formation (B) and channel/receptor plasticity, including channel internalization through endocytosis (C).Abbreviations: EC, extracellular; IC, intracellular.
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