Assessment, Treatment and Translational Research in Recontructive Surgery
Epidemiology of diseases
Basic epidemiologic research
Clinical epidemiology
Biostatistics
Effects of screening and clinical interventions on population health
Determinants and primary prevention
Clinical research in general practice.
Implementation of diagnostic and interventional imaging technology
Assessment of diagnostic and interventional imaging technology
Development of acquisition and processing techniques for diagnostic imaging
Structuring of medical knowledge
Structuring of medical data
Netherlands Institute for Health Sciences (NIHES)
Assessment, aetiology and course of child and adolescent psychiatry
Adaptation of (future) patients to disease and treatment in order to improve counselling and guidance
Health care management (theme 3)
Quality and efficiency in health care (theme 2)
Competition and regulation in health care (theme 1)
Netherlands Institute for Health Sciences (NIHES)
EMC NIHES-01-50-01-A - Assessment, Treatment and Translational Research in Recontructive
Surgery
Programme in brief design
The program `Assessment, Treatment and Translational Research in Reconstructive Surgery¿ relates to research questions derived from three main patient groups: upper extremity disorders, craniofacial disorders and patients requiring reconstructions after oncological resection. Furthermore wound healing plays an important role in reconstructive surgery.
Within these three patient groups, we share the same three research topics, which are often interrelated.
1) Development and evaluation of innovative clinical interventions, either in randomized or cohort studies.
2) Development and application of new assessment tools, such as new imaging techniques and measurement tools to be used for both diagnosis and outcome assessment.
3) Development and evaluation of innovative experimental interventions with a close relation to the clinic.
Most clinical and translational research is multidisciplinary, resulting in collaboration with a large number of clinical and preclinical departments.
Key figures
Department SP1 SP2 SP3 SP4 Sptot T1 T2 T3 Ttot IS FS OP Ptot oral and maxillofacial surgery 0,2 0 0 0 0,2
pediatric psychiatry 0,1 0 0 0 0,1
plastic and reconstructive
surgery 3,9 0 0 4,65 8,55
rehabilitation 0 0 0 0,5 0,5
Total 4,2 0 0 5,15 9,35 6 1 0 7 49 4 1 61
Thesis
Bannink, N. (2010, september 01). Obstructive sleep apnea in children with syndromic craniosynostosis. EUR (185 pag.) (Rotterdam: Optima Grafische Communicatie). Prom./coprom.: Prof. Dr. S.E.R. Hovius, Dr. I.M.J. Mathijssen & Dr. K.F.M.
Joosten.
Bruggeman, J.P. (2010, oktober 22). Biodegradable polyol-based polymers. A polymer platform for biomedical applications.
EUR. Prom./coprom.: Prof. Dr. S.E.R. Hovius.
Molenaar, H.M. (2010, juni 10). Measuring hand strength in children. EUR. Prom./coprom.: Prof. Dr. S.E.R. Hovius & Prof. Dr.
H.J. Stam.
Rath, S. (2010, juni 04). Early active mobilization of tendon transfers. EUR. Prom./coprom.: Prof. Dr. S.E.R. Hovius & Prof. Dr.
H.J. Stam.
Stokvis, A. (2010, september 24). Surgical management of painful neuromas. EUR. Prom./coprom.: Prof. Dr. S.E.R. Hovius.
Ultee, J. (2010, juni 15). Outcome following peripheral nerve injury of the forearm. EUR. Prom./coprom.: Prof. Dr. S.E.R. Hovius.
Versnel, S.L.. Let¿s face it! Causes, treatment and consequences of rare facial clefts. EUR. Prom./coprom.: Prof. Dr. S.E.R.
Hovius & Prof.Dr. J. Passchier.
Artikel/Letter to the editor
Ananta, M & Coert, J.H. (2010). Prevention of wound infection after release of Apert acrosyndactyly. Plastic and Reconstructive Surgery, 126(1), 42e-43e.
Bannink, N., Mathijssen, I.M.J. & Joosten, K.F.M. (2010). Can parents predict obstructive sleep apnea in children with syndromic or complex craniosynostosis? International Journal of Oral and Maxillofacial Surgery, 39, 421-423.
Bannink, N., Maliepaard, M., Raat, H., Joosten, K.F.M. & Mathijssen, I.M.J. (2010). Health-related quality of life in children and adolescent with syndromic craniosynostosis. Journal of Plastic, Reconstructive & Aesthetic Surgery, 63, 1972-1981.
Bannink, N., Nout, E., Wolvius, E.B., Hoeve, L.J., Joosten, K.F.M. & Mathijssen, I.M.J. (2010). Obstructive sleep apnea in children with syndromic craniosynostosis: long-term respiratory outcome of midface advancement. International Journal of Oral and Maxillofacial Surgery, 39(2), 115-121.
Bannink, N., Mathijssen, I.M.J. & Joosten, K.F.M. (2010). Use of ambulatory polysomnography in children with syndromic craniosynostisis. Journal of Craniofacial Surgery, 21(5), 1365-1368.
Boender, Z.J., Ultee, J. & Hovius, S.E.R. (2010). Cognitive capacity: No association with recovery of sensibility by Semmes Weinstein test score after peripheral nerve injury of the forearm. Journal of Plastic, Reconstructive & Aesthetic Surgery, 63(2), 354-359.
Bruggeman, J.P., Bettinger, CJ & Langer, R (2010). Biodegradable xylitol-based elastomers: In vivo behavior and biocompatibility. Journal of Biomedical Materials Research Part A, 95A(1), 92-104.
Coert, J.H. (2010). Pathophysiology of nerve regeneration and nerve reconstruction in burned patients. Burns, 36(5), 593-598.
Colaris, J.W., Linden, M.W. van der, Selles, R.W., Coene, N, Allema, J.H. & Verhaar, J.A.N. (2010). Pronation and supination after forearm fractures in children: Reliability of visual estimation and conventional goniometry measurement. Injury-International Journal of the Care of the Injured, 41(6), 643-646.
Damen, T.H.C., Timman, R., Kunst, EH, Gopie, JP, Bresser, P.J.C., Seynaeve, C., Menke - Pluijmers, M.B.E., Mureau, M.A.M., Hofer, S.O.P. & Tibben, A. (2010). High satisfaction rates in women after DIEP flap breast reconstruction. Journal of Plastic, Reconstructive & Aesthetic Surgery, 63(1), 93-100.
Driel, A.A. van, Mureau, M.A.M., Goldstein, DP, Gilbert, RW, Irish, J.C., Gullane, P.J., Neligan, P.C. & Hofer, S.O.P. (2010).
Aesthetic and Oncologic Outcome after Microsurgical Reconstruction of Complex Scalp and Forehead Defects after Malignant Tumor Resection: An Algorithm for Treatment. Plastic and Reconstructive Surgery, 126(2), 460-470.
Florisson, J.M.G., Veelen, M.L.C. van, Bannink, N., Adrichem, L.N.A. van, Meulen, J.J.N.M. van der, Bartels, M.C. & Mathijssen, I.M.J. (2010). Papilledema in Isolated Single-Suture Craniosynostosis: Prevalence and Predictive Factors. Journal of
Craniofacial Surgery, 21(1), 20-24.
Gooskens, S.L.M., Oranje, A.P., Adrichem, L.N.A. van, Waard- van der Spek, F.B. de, Hollander, J.C. den, Ven, C.P. van de &
Heuvel-Eibrink, M.M. van den (2010). Imatinib mesylate for children with dermatofibrosarcoma protuberans (DFSP). Pediatric Blood & Cancer, 55, 369-373.
Haeseker, G.A., Mureau, M.A.M. & Faber, F.W.M. (2010). Lateral Column Lengthening for Acquired Adult Flatfoot Deformity Caused by Posterior Tibial Tendon Dysfunction Stage II: A Retrospective Comparison of Calcaneus Osteotomy with Calcaneocuboid Distraction Arthrodesis. Journal of Foot & Ankle Surgery, 49(4), 380-384.
Hofer, S.O.P. & Mureau, M.A.M. (2010). Pedicled Perforator Flaps in the Head and Neck. Clinics in Plastic Surgery, 37(4), 627- +.
Hossaini, S.M., Duraku, L., Sarac, C, Jongen, J.L.M. & Holstege, J.C. (2010). Differential distribution of activated spinal neurons containing glycine and/or GABA and expressing c-fos in acute and chronic pain models. Pain, 151(2), 356-365.
Huisstede, B.M., Randsdorp, M.S., Coert, J.H., Glerum, S., Middelkoop, M. van & Koes, B.W. (2010). Carpal Tunnel Syndrome.
Part II: Effectiveness of Surgical Treatments-A Systematic Review. Archives of Physical Medicine and Rehabilitation, 91(7), 1005-1024.
Jong, T. de, Bannink, N., Bredero-Boelhouwer, H.H., Veelen, M.L.C. van, Bartels, M.C., Hoeve, L.J., Hoogeboom, A.J.M., Wolvius, E.B., Lequin, M.H., Meulen, J.J.N.M. van der, Adrichem, L.N.A. van, Vaandrager, J.M., Ongkosuwito, E.M., Joosten, K.F.M. & Mathijssen, I.M.J. (2010). Long-term functional outcome in 167 patients with syndromic craniosynostosis; defining a syndrome-specific risk profile. Journal of Plastic, Reconstructive & Aesthetic Surgery, 63(10), 1635-1641.
Korstanje, J.H., Selles, R.W., Stam, H.J., Hovius, S.E.R. & Bosch, J.G. (2010). Development and validation of ultrasound speckle tracking to quantify tendon displacement. Journal of Biomechanics, 43(7), 1373-1379.
Korstanje, J.H., Schreuders, A.R., Sijde, K. van der, Hovius, S.E.R., Bosch, J.G. & Selles, R.W. (2010). Ultrasonographic Assessment of Long Finger Tendon Excursion in Zone V During Passive and Active Tendon Gliding Exercises. Journal of Hand Surgery-American Volume, 35A(4), 559-565.
Kusters, F.J.G., Walbeehm, E.T. & Niehof, S.P. (2010). Neural influence on cold induced vasodilatation using a new set-up for bilateral measurement in the rat hind limb. Journal of Neuroscience Methods, 193(1), 100-105.
Mathijssen, I.M.J. & Meulen, J.C. van der (2010). Guidelines for reconstruction of the eyelids and canthal regions. Journal of Plastic, Reconstructive & Aesthetic Surgery, 63(9), 1420-1433.
Molenaar, H.M., Selles, R.W., Zuidam, J.M., Willemsen, S.P., Stam, H.J. & Hovius, S.E.R. (2010). Growth Diagrams for Grip Strength in Children. Clinical Orthopaedics & Related Research, 468(1), 217-223.
Molenaar, H.M., Kraker, M. de, Zuidam, J.M., Hovius, S.E.R., Stam, H.J. & Selles, R.W. (2010). Visual Feedback and Weight Reduction of a Grip Strength Dynamometer Do Not Increase Reliability in Healthy Children. Journal of Hand Therapy, 23(3), 272-279.
Moolenburgh, S.E., Mac Lennan, L.M., Levendag, P.C., Munte, K., Scholtemeijer, M., Hofer, S.O.P. & Mureau, M.A.M. (2010).
Nasal Reconstruction after Malignant Tumor Resection: An Algorithm for Treatment. Plastic and Reconstructive Surgery, 126(1), 97-105.
Nijhuis, T.H.J., Brzezicki, G, Klimczak, A & Siemionow, M (2010). ISOGENIC VENOUS GRAFT SUPPORTED WITH BONE MARROW STROMAL CELLS AS A NATURAL CONDUIT FOR BRIDGING A 20 mm NERVE GAP. Microsurgery, 30(8), 639- 645.
Nijhuis, T.H.J., Smits, E.S., Jaquet, J.B., Oosterom, F.J.T. van, Selles, R.W. & Hovius, S.E.R. (2010). PREVALENCE AND SEVERITY OF COLD INTOLERANCE IN PATIENTS AFTER HAND FRACTURE. Journal of Hand Surgery-European Volume, 35E(4), 306-311.
Nout, E., Mathijssen, I.M.J., Meulen, J.J.N.M. van der, Veelen, M.L.C. van, Koning, A.H.J., Lequin, M.H. & Wolvius, E.B. (2010).
Internal carotid dissection after Le Fort III distraction in Apert syndrome: A case report. Journal of Cranio-Maxillofacial Surgery, 38(7), 529-533.
Nout, E., Bouw, F.P., Veenland, J.F., Hop, W.C.J., Wal, K.G.H. van der, Mathijssen, I.M.J. & Wolvius, E.B. (2010). Three- Dimensional Airway Changes after Le Fort III Advancement in Syndromic Craniosynostosis Patients. Plastic and Reconstructive Surgery, 126(2), 564-571.
Ongkosuwito, E.M., Gijt, P de, Wattel, E, Carels, CEL & Kuijpers-Jagtman, A.M. (2010). Dental Development in Hemifacial Microsomia. Journal of Dental Research, 89(12), 1368-1372.
Pourrier, SD, Nieuwstraten, W., Cranenburgh, B Van, Schreuders, A.R., Stam, H.J. & Selles, R.W. (2010). Three cases of referred sensation in traumatic nerve injury of the hand: implication for understanding central nervous system reorganization.
Journal of Rehabilitation Medicine, 42(4), 357-361.
Rath, S., Schreuders, A.R., Stam, H.J., Hovius, S.E.R. & Selles, R.W. (2010). Early Active Motion versus Immobilization after Tendon Transfer for Foot Drop Deformity: A Randomized Clinical Trial. Clinical Orthopaedics & Related Research, 468(9), 2477-2484.
Rath, S., Schreuders, A.R. & Selles, R.W. (2010). Early postoperative active mobilisation versus immobilisation following tibialis posterior tendon transfer for foot-drop correction in patients with Hansen's disease. Journal of Plastic, Reconstructive &
Aesthetic Surgery, 63(3), 554-560.
Rozendaal, A.M., Luijsterburg, A.J.M., Mohangoo, A.D., Ongkosuwito, E.M., Anthony, S. & Vermeij-Keers, C. (2010). Validation of the NVSCA Registry for Common Oral Clefts: Study Design and First Results. Cleft Palate-Craniofacial Journal, 47(5), 534- 543.
Schuitema, O.P., Mathijssen, I.M.J. & Mureau, M.A.M. (2010). Reconstruction of an extensive traumatic hemipelvectomy defect using a free lower leg fillet flap. Journal of Plastic, Reconstructive & Aesthetic Surgery, 63(1), E116-E117.
Soeters, J.N.M., Selles, R.W. & Stam, H.J. (2010). Intrinsic plus positioning of fingers due to bowstringing at the metacarpophalangeal joint. Journal of Hand Surgery-European Volume, 35E(2), 150-151.
Spaans, AJ, Slijper, H.P., Moojen, TM & Feitz, R. (2010). Open wedge correctieosteotomie voor malunited extra-articulaire distale radiusfracturen. Nederlands Tijdschrift voor Plastische Chirurgie, 1, 14-20.
Spiegelberg, L., Djasim, U.M., Neck, J.W. van, Wolvius, E.B. & Wal, K.G.H. van der (2010). Hyperbaric Oxygen Therapy in the Management of Radiation-Induced Injury in the Head and Neck Region: A Review of the Literature. Journal of Oral and Maxillofacial Surgery, 68(8), 1732-1739.
Stenekes, MW, Coert, J.H., Nicolai, JPA, Mulder, T., Geertzen, JHB, Paans, AM & Jong, B.M. de (2010). Cerebral consequences of dynamic immobilisation after primary digital flexor tendon repair. Journal of Plastic, Reconstructive &
Aesthetic Surgery, 63(12), 1953-1961.
Stokvis, A., Coert, J.H. & Neck, J.W. van (2010). Insufficient pain relief after surgical neuroma treatment: Prognostic factors and central sensitisation. Journal of Plastic, Reconstructive & Aesthetic Surgery, 63(9), 1538-1543.
Stokvis, A., Avoort, D.J.J.C. van der, Neck, J.W. van, Hovius, S.E.R. & Coert, J.H. (2010). Surgical management of neuroma pain: A prospective follow-up study. Pain, 151(3), 862-869.
Twigg, SRF, Wilkie, A.O.M., Versnel, S.L. & Mathijssen, I.M.J. (2010). Median facial cleft dysmorphism in three siblings: case report and review of the literature. Cleft Palate-Craniofacial Journal, 47(4), 430-430.
Verseijden, F., Sluijs, S.J. van, Farrell, E.J., Neck, J.W. van, Hovius, S.E.R., Hofer, S.O.P. & Osch, G.J.V.M. van (2010).
Prevascular Structures Promote Vascularization in Engineered Human Adipose Tissue Constructs Upon Implantation. Cell Transplantation, 19(8), 1007-1020.
Versnel, S.L., Duivenvoorden, H.J., Passchier, J. & Mathijssen, I.M.J. (2010). Satisfaction with facial appearance and its determinants in adults with severe congenital facial disfigurement: A case-referent study. Journal of Plastic, Reconstructive &
Aesthetic Surgery, 63(10), 1642-1649.
Visser, N.J., Damen, T.H.C., Timman, R., Hofer, S.O.P. & Mureau, M.A.M. (2010). Surgical Results, Aesthetic Outcome, and Patient Satisfaction after Microsurgical Autologous Breast Reconstruction following Failed Implant Reconstruction. Plastic and Reconstructive Surgery, 126(1), 26-36.
Walbeehm, E.T. (2010). European locums Reconsider the locum system. British Medical Journal, 340.
Walbeehm, E.T. (2010). Locum issues Time to tackle the system. British Medical Journal, 341.
Zuidam, J.M., Kraker, M. de, Selles, R.W. & Hovius, S.E.R. (2010). Evaluation of Function and Appearance of Adults With Untreated Triphalangeal Thumbs. Journal of Hand Surgery-American Volume, 35A(7), 1146-1152.
Zuidam, J.M., Dees, E.E.C., Selles, R.W. & Hovius, S.E.R. (2010). IMPLICATIONS FOR TREATMENT OF VARIATIONS IN LENGTH OF THE FIRST METACARPAL IN DIFFERENT TYPES OF TRIPHALANGEAL THUMBS. Journal of Hand Surgery- European Volume, 35E(1), 65-69.
Zuijdendorp, H.M., Tra, W.M.W., Neck, J.W. van, Mollis, L & Coert, J.H. (2010). Delay of denervation atrophy by sensory protection in an end-to-side neurorrhaphy model: A pilot study. Journal of Plastic, Reconstructive & Aesthetic Surgery, 63(12), 1949-1952.
Part of book - abstract
Hovius, S.E.R. & Nieuwenhoven, C.A. van (2010). Clinical: Section VI Nerves: Nerve compression syndromes of the upper limb.
In JR Urbaniak (Ed.), Hand Surgery Worldwide, International Reconstruction of a ¿Beautiful and Ready Instrument of the Mind (pp. 359-370).
Hovius, S.E.R. (2010). Post traumatic Stress Disorder (PTSD). In FESSH 2010 ¿ Bucharest, Instructional Course (pp. 31-36).
Meulen, J.C. van der, Groot Swanson, G de & Hovius, S.E.R. (2010). History: The Netherlands. In JR Urbaniak (Ed.), Hand Surgery Worldwide, International Reconstruction of a ¿Beautiful and ready instrument of the mind (pp. 203-209).
Nieuwenhoven, C.A. van & Hovius, S.E.R. (2010). Carpal Tunnel Syndrome in Children. In Moon Sang Chung (Ed.), Hand Surgery 2010 IFSSH (International Federation of Societies for Surgery of the Hand (pp. 145-148).
EMC NIHES-01-64-01 - Epidemiology of diseases
Programme in brief design
This program includes scientific research in cardiovascular epidemiology, neuroepidemiology and ophthalmologic epidemiology.
Cardiovascular epidemiologic research focuses on the determinants of atherosclerosis and coronary heart disease in the elderly, and on cardiovascular diseases in women. The research is based on the Rotterdam Study and addresses inflammation markers and hemostasis as determinants of cardiovascular diseases in the elderly, and the effects of menopause, endogenous
hormones and hormone replacement therapy in women. Neuroepidemiologic research focuses on the etiology of
neurodegenerative and cerebrovascular diseases, including dementia and Alzheimer's disease, Parkinson's disease, stroke and cerebral white matter lesions. The research emphasizes the role of vascular factors in the etiology of these diseases, with use of state of the art neuroimaging techniques. Ophthalmological epidemiologic research focuses on determinants of macula degeneration and glaucoma. The emphasis is on the putative role of genetic factors and vascular factors in etiology of these diseases.
Key figures
Department SP1 SP2 SP3 SP4 Sptot T1 T2 T3 Ttot IS FS OP Ptot
epidemiology 3,23 10,68 3,08 0,75 17,74
internal medicine 0 1,5 0 0 1,5
neurology 0,2 0 0 0 0,2
Total 3,43 12,18 3,08 0,75 19,44 2 0 0 2 127 0 0 129
Thesis
Dehghan, A. (2010, maart 31). Novel risk factors for type II diabetes mellitus and coronary heart disease. EUR. Prom./coprom.:
Prof. Dr. J.C.M. Witteman & Prof. Dr. E.J.G. Sijbrands.
Mook-Kanamori, D.O. (2010, november 24). Genetic and environmental influences on early growth. The Generation R Study.
EUR (241 pag.) (Rotterdam: Optima Grafische Communicatie). Prom./coprom.: Prof. Dr. A. Hofman, Prof. Dr. E.A.P. Steegers &
Dr. V.W.V.K. Jaddoe.
Artikel/Letter to the editor
Alberts, VP, Bos, M.J., Koudstaal, P.J., Hofman, A., Witteman, J.C.M., Stricker, B.H.C. & Breteler, M.M.B. (2010). Heart failure and the risk of stroke: the Rotterdam Study. European Journal of Epidemiology, 25(11), 807-812.
Anttila, V, Stefansson, H, Kallela, M, Todt, U, Terwindt, G.M., Calafato, MS, Nyholt, DR, Dimas, AS, Freilinger, T, Muller- Myhsok, B, Artto, V, Inouye, M, Alakurtti, K, Kaunisto, MA, Hamalainen, E, Vries, B de, Stam, AH, Weller, CM, Heinze, A, Heinze-Kuhn, K, Goebel, I, Borck, G, Gobel, H, Steinberg, S, Wolf, C, Bjornsson, A, Gudmundsson, G, Kirchmann, M, Hauge, A, Werge, T, Schoenen, J., Eriksson, JG, Hagen, K, Stovner, L, Wichmann, E, Meitinger, T, Alexander, M, Moebus, S, Schreiber, S., Aulchenko, Y.S., Breteler, M.M.B., Uitterlinden, A.G., Hofman, A., Duijn, C.M. van, Tikka-Kleemola, P, Vepsalainen, ., Lucae, S, Tozzi, F, Muglia, P, Barrett, J, Kaprio, J, Farkkila, M, Peltonen, L., Stefansson, K, Zwart, JA, Ferrari, M.D., Olesen, J, Daly, M., Wessman, M, Maagdenberg, A.M.J.M., Dichgans, M, Kubisch, C, Dermitzakis, ET, Frants, R.R. &
Palotie, A (2010). Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1. Nature Genetics, 42(10), 869-873.
Baas, DC, Ho, L., Ennis, S, Merriam, JE, Tanck, M.W.T., Uitterlinden, A.G., Jong, P.T.V.M. de, Cree, AJ, Griffiths, HL, Rivadeneira, F., Hofman, A., Duijn, C.M. van, Smith, R.T., Barile, GR, Gorgels, TGMF, Vingerling, J.R., Klaver, C.C.W., Lotery, AJ, Allikmets, R. & Bergen, A.A.B. (2010). The Complement Component 5 Gene and Age-Related Macular Degeneration.
Ophthalmology, 117(3), 500-511.
Baas, DC, Despriet, D.D., Gorgels, T.G.M.F., Bergeron-Sawitzke, J, Uitterlinden, A.G., Hofman, A., Duijn, C.M. van, Merriam, JE, Smith, R.T., Barile, GR, Brink, J.B., Vingerling, J.R., Klaver, C.C.W., Allikmets, R., Dean, M & Bergen, A.A.B. (2010). The ERCC6 Gene and Age-Related Macular Degeneration. PLoS One, 5(11).
Bakker, R., Pluimgraaff, L.E., Steegers, E.A.P., Raat, H., Tiemeier, H.W., Hofman, A. & Jaddoe, V.W.V.K. (2010). Associations of light and moderate maternal alcohol consumption with fetal growth characteristics in different periods of pregnancy: The Generation R Study. International Journal of Epidemiology, 39(3), 777-789.
Bakker, R., Steegers, E.A.P., Obradov, A, Raat, H., Hofman, A. & Jaddoe, V.W.V.K. (2010). Maternal caffeine intake from coffee and tea, fetal growth, and the risks of adverse birth outcomes: the Generation R Study. American Journal of Clinical Nutrition, 91(6), 1691-1698.
Bakker, R., Steegers, E.A.P., Mackenbach, J.P., Hofman, A. & Jaddoe, V.W.V.K. (2010). Maternal smoking and blood pressure in different trimesters of pregnancy: The Generation R Study. Journal of Hypertension, 28(11), 2210-2218.
Barbalic, M, Dupuis, J, Dehghan, A., Bis, JC, Hoogeveen, RC, Schnabel, RB, Nambi, V, Bretler, M, Smith, NL, Peters, A., Lu, C, Tracy, RP, Aleksic, N, Heeriga, J, Keaney, JF, Rice, K, Lip, G.Y.H., Vasan, RS, Glazer, NL, Larson, MG, Uitterlinden, A.G., Yamamoto, J, Durda, P, Haritunians, T, Psaty, B.M., Boerwinkle, E., Hofman, A., Koenig, W., Jenny, NS, Witteman, J.C.M., Ballantyne, C. & Benjamin, EJ (2010). Large-scale genomic studies reveal central role of ABO in sP-selectin and sICAM-1 levels. Human Molecular Genetics, 19(9), 1863-1872.
Batenburg-Eddes, T. van, Groot, L. de, Steegers, E.A.P., Hofman, A., Jaddoe, V.W.V.K., Verhulst, F.C. & Tiemeier, H.W.
(2010). Fetal Programming of Infant Neuromotor Development: The Generation R Study. Pediatric Research, 67(2), 132-137.
Becker, M.L., Visser, L.E., Schaik, R.H.N. van, Hofman, A., Uitterlinden, A.G. & Stricker, B.H.C. (2010). Influence of genetic variation in CYP3A4 and ABCB1 on dose decrease or switching during simvastatin and atorvastatin therapy.
Pharmacoepidemiology and Drug Safety, 19(1), 75-81.
Becker, M.L., Visser, L.E., Schaik, R.H.N. van, Hofman, A., Uitterlinden, A.G. & Stricker, B.H.C. (2010). Interaction between polymorphisms in the OCT1 and MATE1 transporter and metformin response. Pharmacogenetics Genomics, 20(1), 38-44.
Beurskens, L.W.J.E., Tibboel, D., Lindemans, J., Duvekot, J.J., Overbeek, T.E., Veenma, D.C.M., Klein, A. de, Greer, JJ &
Steegers-Theunissen, R.P.M. (2010). Retinol Status of Newborn Infants Is Associated With Congenital Diaphragmatic Hernia.
Pediatrics, 126(4), 712-720.
Blauw, HM, Al-Chalabi, A, Andersen, PM, Vught, PWJ Van, Diekstra, FP, Es, MA van, Saris, CGJ, Groen, EJN, Rheenen, W van, Koppers, M, Slot, R van 't, Strengman, E., Estrada, K, Rivadeneira, F., Hofman, A., Uitterlinden, A.G., Kiemeney, LA, Vermeulen, SHM, Birve, A, Waibel, S, Meyer, T, Cronin, S, McLaughlin, RL, Hardiman, O, Sapp, PC, Tobin, MD, Wain, LV, Tomik, B, Slowik, A, Lemmens, R, Rujescu, D, Schulte, C, Gasser, T., Brown, RH, Landers, JE, Robberecht, W, Ludolph, A.C., Ophoff, R.A., Veldink, J.H. & Berg, L.H. van den (2010). A large genome scan for rare CNVs in amyotrophic lateral sclerosis.
Human Molecular Genetics, 19(20), 4091-4099.
Blom, E.A., Jansen, P.W., Verhulst, F.C., Hofman, A., Raat, H., Jaddoe, V.W.V.K., Coolman, M., Steegers, E.A.P. & Tiemeier, H.W. (2010). Perinatal complications increase the risk of postpartum depression. The Generation R Study. Bjog-An International Journal of Obstetrics and Gynaecology, 117(11), 1390-1398.
Boer, R. de, Vrooman, H.A., Ikram, M.A., Vernooij, M.W., Breteler, M.M.B., Lugt, A. van der & Niessen, W.J. (2010). Accuracy and reproducibility study of automatic MRI brain tissue segmentation methods. Neuroimage, 51(3), 1047-1056.
Brugts, J.J., Isaacs, A.J., Boersma, E., Duijn, C.M. van, Uitterlinden, A.G., Remme, W, Bertrand, M, Ninomiya, T, Ceconi, C., Chalmers, J, MacMahon, S, Fox, K, Ferrari, R., Witteman, J.C.M., Danser, A.H.J., Simoons, M.L. & Maat, M.P.M. de (2010).
Genetic determinants of treatment benefit of the angiotensin-converting enzyme-inhibitor perindopril in patients with stable coronary artery disease. European Heart Journal, 31(15), 1854-1864.
Brugts, M.P., Duijn, C.M. van, Hofland, L.J., Witteman, J.C.M., Lamberts, S.W.J & Janssen, J.A.M.J.L. (2010). IGF-I Bioactivity in an Elderly Population Relation to Insulin Sensitivity, Insulin Levels, and the Metabolic Syndrome. Diabetes, 59(2), 505-508.
Combarros, O, Warden, DR, Hammond, N, Cortina-Borja, M, Belbin, O, Lehmann, MG, Wilcock, GK, Brown, K., Kehoe, PG, Barber, R, Coto, E, Alvarez, V, Deloukas, P, Gwilliam, R, Heun, R, Kolsch, H, Mateo, I, Oulhaj, A, Arias-Vasquez, A, Schuur, M., Aulchenko, Y.S., Ikram, M.A., Breteler, M.M.B., Duijn, C.M. van, Morgan, K., Smith, AD & Lehmann, DJ (2010). The dopamine beta-hydroxylase-1021C/T polymorphism is associated with the risk of Alzheimer's disease in the Epistasis Project. BMC Medical Genetics, 11.
Coolman, M., Groot, C.J.M. de, Jaddoe, V.W.V.K., Hofman, A., Raat, H. & Steegers, E.A.P. (2010). Medical record validation of maternally reported history of preeclampsia. Journal of Clinical Epidemiology, 63(8), 932-937.
Czudowska, M.A., Ramdas, W.D., Wolfs, R.C.W., Hofman, A., Jong, P.T.V.M. de, Vingerling, J.R. & Jansonius, N.M. (2010).
Incidence of Glaucomatous Visual Field Loss: A Ten-Year Follow-up from the Rotterdam Study. Ophthalmology, 117(9), 1705- 1712.
Debette, S, Bis, JC, Fornage, M, Schmidt, H., Ikram, M.A., Sigurdsson, S, Heiss, G, Struchalin, M, Smith, AV, Lugt, A. van der, DeCarli, C., Lumley, T, Knopman, DS, Enzinger, C, Eiriksdottir, G, Koudstaal, P.J., DeStefano, AL, Psaty, B.M., Dufouil, C., Catellier, DJ, Fazekas, F., Aspelund, T, Aulchenko, Y.S., Beiser, A, Rotter, JI, Tzourio, C., Shibata, DK, Tscherner, M, Harris, T.B., Rivadeneira, F., Atwood, LD, Rice, K, Gottesman, RF, Buchem, M.A. van, Uitterlinden, A.G., Kelly-Hayes, M, Cushman, M., Zhu, YC, Boerwinkle, E., Gudnason, V, Hofman, A., Romero, JR, Lopez, O, Duijn, C.M. van, Au, R., Heckbert, SR, Wolf, PA, Mosley, TH, Seshadri, S, Breteler, M.M.B., Schmidt, R., Launer, L.J. & Longstreth, W.T. (2010). Genome-Wide Association Studies of MRI-Defined Brain Infarcts Meta-Analysis From the CHARGE Consortium. Stroke, 41(2), 210-217.
Devore, E.E., Grodstein, F., Rooij, F.J.A. van, Hofman, A., Stampfer, M.J., Witteman, J.C.M. & Breteler, M.M.B. (2010). Dietary Antioxidants and Long-term Risk of Dementia. Archives of Neurology, 67(7), 819-825.
Duijts, L., Jaddoe, V.W.V.K., Hofman, A. & Moll, H.A. (2010). Prolonged and Exclusive Breastfeeding Reduces the Risk of Infectious Diseases in Infancy. Pediatrics, 126(1), E18-E25.
Durme, Y.M.T.A. van, Eijgelsheim, M., Joos, G.F., Hofman, A., Uitterlinden, A.G., Brusselle, GG & Stricker, B.H.C. (2010).
Hedgehog-interacting protein is a COPD susceptibility gene: the Rotterdam Study. European Respiratory Journal, 36(1), 89-95.
Durmus, B., Mook-Kanamori, D.O., Holzhauer, S., Hofman, A., Beek, E.M. van der, Boehm, G., Steegers, E.A.P. & Jaddoe, V.W.V.K. (2010). Growth in foetal life and infancy is associated with abdominal adiposity at the age of 2 years: The Generation R Study. Clinical Endocrinology, 72(5), 633-640.
Eijgelsheim, M., Newton-Cheh, C, Sotoodehnia, N, Bakker, PIW de, Muller, M., Morrison, AC, Smith, AV, Isaacs, A.J., Sanna, S, Dorr, M, Navarro, P, Fuchsberger, C, Nolte, I.M., Geus, E.J.C. de, Estrada, K, Hwang, SJ, Bis, JC, Ruckert, IM, Alonso, A., Launer, L.J., Hottenga, J.J., Rivadeneira Ramirez, F., Noseworthy, PA, Rice, KM, Perz, S, Arking, DE, Spector, T.D., Kors, J.A., Aulchenko, Y.S., Tarasov, KV, Homuth, G., Wild, SH, Marroni, F, Gieger, C, Licht, CM, Prineas, RJ, Hofman, A., Rotter, JI, Hicks, AA, Ernst, F, Najjar, SS, Wright, AF, Peters, A., Fox, ER, Oostra, B.A., Kroemer, HK, Couper, D, Volzke, H, Campbell, H, Meitinger, T, Uda, M, Witteman, J.C.M., Psaty, B.M., Wichmann, HE, Harris, T.B., Kaab, S, Siscovick, D.S., Jamshidi, Y,
Uitterlinden, A.G., Folsom, A.R., Larson, MG, Wilson, JF, Penninx, BW, Snieder, H, Pramstaller, P.P., Duijn, C.M. van, Lakatta, EG, Felix, SB, Gudnason, V, Pfeufer, A, Heckbert, SR, Stricker, B.H.C., Boerwinkle, E. & O'Donnell, CJ (2010). Genome-wide association analysis identifies multiple loci related to resting heart rate. Human Molecular Genetics, 19(19), 3885-3894.
Elias-Smale, S.E., Odink, A.E., Wieberdink, R.G., Hofman, A., Hunink, M.G.M., Krestin, G.P., Koudstaal, P.J., Breteler, M.M.B., Lugt, A. van der & Witteman, J.C.M. (2010). Carotid, aortic arch and coronary calcification are related to history of stroke: The Rotterdam Study. Atherosclerosis, 212(2), 656-660.
Elias-Smale, S.E., Proenca, RV, Koller, M.T., Kavousi, M., Rooij, F.J.A. van, Hunink, M.G.M., Steyerberg, E.W., Hofman, A., Oudkerk, M.. & Witteman, J.C.M. (2010). Coronary Calcium Score Improves Classification of Coronary Heart Disease Risk in the Elderly The Rotterdam Study. Journal of the American College of Cardiology, 56(17), 1407-1414.
Ellinor, PT, Lunetta, KL, Glazer, NL, Pfeufer, A, Alonso, A., Chung, MK, Sinner, MF, Bakker, PIW de, Mueller, M, Lubitz, SA, Fox, E, Darbar, D, Smith, NL, Smith, JD, Schnabel, RB, Soliman, EZ, Rice, KM, Wagoner, DR Van, Beckmann, BM, Noord, C.
van, Wang, K, Ehret, GB, Rotter, JI, Hazen, SL, Steinbeck, G, Smith, AV, Launer, L.J., Harris, T.B., Makino, S, Nelis, M, Milan, DJ, Perz, S, Esko, T, Kottgen, A, Moebus, S, Newton-Cheh, C, Li, M., Moehlenkamp, S, Wang, T.J., Kao, WHL, Vasan, RS, Nothen, MM, MacRae, CA, Stricker, B.H.C., Hofman, A., Uitterlinden, A.G., Levy, D., Boerwinkle, E., Metspalu, A, Topol, E.J., Chakravarti, A, Gudnason, V, Psaty, B.M., Roden, DM, Meitinger, T, Wichmann, HE, Witteman, J.C.M., Barnard, J, Arking, DE, Benjamin, EJ, Heckbert, SR & Kaab, S (2010). Common variants in KCNN3 are associated with lone atrial fibrillation. Nature Genetics, 42(3), 240-U36.
Euser, S.M., Sattar, N, Witteman, J.C.M., Bollen, ELEM, Sijbrands, E.J.G., Hofman, A., Perry, IJ, Breteler, M.M.B. &
Westendorp, R.G.J. (2010). A Prospective Analysis of Elevated Fasting Glucose Levels and Cognitive Function in Older People Results From PROSPER and the Rotterdam Study. Diabetes, 59(7), 1601-1607.
Flohil, S.C., Vries, E. de, Meurs, J.B.J. van, Fang, Y., Stricker, B.H.C., Uitterlinden, A.G. & Nijsten, T.E.C. (2010). Vitamin D- binding protein polymorphisms are not associated with development of (multiple) basal cell carcinomas. Experimental Dermatology, 19(12), 1103-1105.
Freathy, RM, Mook-Kanamori, D.O., Sovio, U, Prokopenko, I, Timpson, NJ, Berry, DJ, Warrington, NM, Widen, E, Hottenga, J.J., Kaakinen, M, Lange, LA, Bradfield, JP, Kerkhof, M., Marsh, JA, Magi, R, Chen, C.M., Lyon, HN, Kirin, M, Adair, LS, Aulchenko, Y.S., Bennett, AJ, Borja, JB, Bouatia-Naji, N, Charoen, P, Coin, LJM, Cousminer, DL, Geus, E.J.C. de, Deloukas, P, Elliott, P, Evans, DM, Froguel, P, Glaser, B., Groves, CJ, Hartikainen, AL, Hassanali, N, Hirschhorn, JN, Hofman, A., Holly, J.M.P., Hypponen, E, Kanoni, S, Knight, BA, Laitinen, J, Lindgren, CM, McArdle, WL, O'Reilly, PF, Pennell, CE, Postma, D.S., Pouta, A, Ramasamy, A, Rayner, NW, Ring, SM, Rivadeneira, F., Shields, BM, Strachan, DP, Surakka, I, Taanila, A, Tiesler, C, Uitterlinden, A.G., Duijn, C.M. van, Wijga, A.H., Willemsen, G, Zhang, HT, Zhao, JH, Wilson, JF, Steegers, E.A.P., Hattersley, A.T., Eriksson, JG, Peltonen, L., Mohlke, KL, Grant, S.F.A., Hakonarson, H, Koppelman, G.H., Dedoussis, GV, Heinrich, J., Gillman, MW, Palmer, LJ, Frayling, T.M., Boomsma, D.I., Smith, G.D., Power, C, Jaddoe, V.W.V.K., Jarvelin, MR & McCarthy, MI (2010). Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight. Nature Genetics, 42(5), 430- U73.
Geelhoed, J.J.M., Taal, H.R., Steegers, E.A., Arends, L.R., Lequin, M., Moll, H.A., Hofman, A., Heijden, A.J. van der & Jaddoe, V.W.V.K. (2010). Kidney growth curves in healthy children from the third trimester of pregnancy until the age of two years. The Generation R Study. Pediatric Nephrology, 25(2), 289-298.
Geelhoed, M.J.J., Steegers, E.A.P., Koper, J.W., Rossum, E.F.C. van, Moll, H.A., Raat, H., Tiemeier, H.W., Hofman, A. &
Jaddoe, V.W.V.K. (2010). Glucocoricoid receptor gene polymorphisms do not affect growth in fetal and early postnatal life. The Generation R Study. BMC Medical Genetics, 11(39).
Gelok, S., Janssens, A.C.J.W., Tiemeier, H.W., Liu, F., Lopez-Leon, S, Zorkoltseva, IV, Axenovich, T.I., Swieten, J.C. van, Uitterlinden, A.G., Hofman, A., Aulchenko, Y.S., Oostra, B.A. & Duijn, C.M. van (2010). A Genome-Wide Screen for Depression in Two Independent Dutch Populations. Biological Psychiatry, 68(2), 187-196.
Groen, E. de, Mohangoo, A.D., Jongste, J.C. de, Wouden, J.C. van der, Moll, H.A., Jaddoe, V.W.V.K., Hofman, A., Koning, H.J.
de & Raat, H. (2010). Early detection and counselling intervention of asthma symptoms in preschool children: study design of a cluster randomised controlled trial. Bmc Public Health, 10, 555.
Groen, H.C., Simons, L., Bouwhuijsen, Q.J.A. van den, Bosboom, EMH, Gijsen, F.J.H., Giessen, A.G. van der, Vosse, F.N. van de, Hofman, A., Steen, A.F.W. van der, Witteman, J.C.M., Lugt, A. van der & Wentzel, J.J. (2010). MRI-based quantification of outflow boundary conditions for computational fluid dynamics of stenosed human carotid arteries. Journal of Biomechanics, 43(12), 2332-2338.
Hancock, DB, Eijgelsheim, M., Wilk, JB, Gharib, SA, Loehr, LR, Marciante, KD, Franceschini, N, Durme, Y.M.T.A. van, Chen, TH, Barr, RG, Schabath, MB, Couper, DJ, Brusselle, GG, Psaty, B.M., Duijn, C.M. van, Rotter, JI, Uitterlinden, A.G., Hofman, A., Punjabi, NM, Rivadeneira Ramirez, F., Morrison, AC, Enright, P.L., North, KE, Heckbert, SR, Lumley, T, Stricker, B.H.C., O'Connor, GT & London, SJ (2010). Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function. Nature Genetics, 42(1), 45-U61.
Heijer, T. den, Lijn, F. van der, Koudstaal, P.J., Hofman, A., Lugt, A. van der, Krestin, G.P., Niessen, W.J. & Breteler, M.M.B.
(2010). A 10-year follow-up of hippocampal volume on magnetic resonance imaging in early dementia and cognitive decline.
Brain, 133, 1163-1172.
Heine-Broring, RC, Brouwer, I.A., Proenca, RV, Rooij, F.J.A. van, Hofman, A., Oudkerk, M., Witteman, J.C.M. & Geleijnse, J.M.
(2010). Intake of fish and marine n-3 fatty acids in relation to coronary calcification: the Rotterdam Study. American Journal of Clinical Nutrition, 91(5), 1317-1323.
Hek, K., Mulder, C.L., Luijendijk, H.J., Duijn, C.M. van, Hofman, A., Uitterlinden, A.G. & Tiemeier, H.W. (2010). The PCLO gene and depressive disorders: replication in a population-based study. Human Molecular Genetics, 19(4), 731-734.
Henrichs, J., Schenk, JJ, Barendregt, C.S., Schmidt, H.G., Steegers, E.A.P., Hofman, A., Jaddoe, V.W.V.K., Moll, H.A., Verhulst, F.C. & Tiemeier, H.W. (2010). Fetal growth from mid- to late pregnancy is associated with infant development: the Generation R Study. Developmental Medicine & Child Neurology, 52(7), 644-651.
Henrichs, J., Schenk, J.J.A.M., Roza, S.J., Berg, M.P. van den, Schmidt, H.G., Steegers, E.A.P., Hofman, A., Jaddoe, V.W.V.K., Verhulst, F.C. & Tiemeier, H.W. (2010). Maternal psychological distress and fetal growth trajectories: The Generation R Study.
Psychological Medicine, 40(4), 633-643.
Henrichs, J., Schokking, J.J., Schenk, JJ, Ghassabian, A., Schmidt, H.G., Visser, T.J., Hooijkaas, H., Muinck Keizer-Schrama, S.M.P.F., Hofman, A., Jaddoe, V.W.V.K., Visser, W., Steegers, E.A.P., Verhulst, F.C., Rijke, Y.B. de & Tiemeier, H.W. (2010).
Maternal Thyroid Function during Early Pregnancy and Cognitive Functioning in Early Childhood: The Generation R Study.
Journal of Clinical Endocrinology and Metabolism, 95(9), 4227-4234.
Herba, C.M., Roza, S.J., Govaert, P., Rossum, J van, Hofman, A., Jaddoe, V.W.V.K., Verhulst, F.C. & Tiemeier, H.W. (2010).
Infant Brain Development and Vulnerability to Later Internalizing Difficulties: The Generation R Study. Journal of the American Academy Child Adolescent Psychiatry, 49(10), 1053-1063.
Ikram, M.A., Vrooman, H.A., Vernooij, M.W., Heijer, T. den, Hofman, A., Niessen, W.J., Lugt, A. van der, Koudstaal, P.J. &
Breteler, M.M.B. (2010). Brain tissue volumes in relation to cognitive function and risk of dementia. Neurobiology of Aging, 31(3), 378-386.
Ikram, M.A., Luijendijk, H.J., Vernooij, M.W., Hofman, A., Niessen, W.J., Lugt, A. van der, Tiemeier, H.W. & Breteler, M.M.B.
(2010). Vascular Brain Disease and Depression in the Elderly. Epidemiology, 21(1), 78-81.
Ikram, M.K., Xueling, S, Jensen, RA, Cotch, MF, Hewitt, AW, Ikram, M.A., Wang, J.J., Klein, R., Klein, B.E.K., Breteler, M.M.B., Cheung, N, Liew, G., Mitchell, P., Uitterlinden, A.G., Rivadeneira, F., Hofman, A., Jong, P.T.V.M. de, Duijn, C.M. van, Kao, L, Cheng, CY, Smith, AV, Glazer, NL, Lumley, T, McKnight, B, Psaty, B.M., Jonasson, F, Eiriksdottir, G, Aspelund, T, Harris, T.B., Launer, L.J., Taylor, KD, Li, XH, Iyengar, SK, Xi, QS, Sivakumaran, TA, Mackey, DA, Macgregor, S, Martin, NG, Young, TL, Bis, JC, Wiggins, KL, Heckbert, SR, Hammond, CJ, Andrew, T., Fahy, S, Attia, J, Holliday, EG, Scott, R.J., Islam, FMA, Rotter, JI, McAuley, AK, Boerwinkle, E., Tai, ES, Gudnason, V, Siscovick, D.S., Vingerling, J.R. & Wong, TY (2010). Four Novel Loci (19q13, 6q24, 12q24, and 5q14) Influence the Microcirculation In Vivo. PLoS Genetics, 6(10), e1001184.
Ikram, M.K., Luijendijk, H.J., Hofman, A., Jong, P.T.V.M. de, Breteler, M.M.B., Vingerling, J.R. & Tiemeier, H.W. (2010). Retinal Vascular Calibers and Risk of Late-Life Depression: The Rotterdam Study. American Journal of Geriatric Psychiatry, 18(5), 452- 455.
Jaddoe, V.W.V.K., Duijn, C.M. van, Heijden, A.J. van der, Mackenbach, J.P., Moll, H.A., Steegers, E.A.P., Tiemeier, H.W., Uitterlinden, A.G., Verhulst, F.C. & Hofman, A. (2010). The Generation R Study: design and cohort update 2010. European Journal of Epidemiology, 25(11), 823-841.
Jansen, P.W., Tiemeier, H.W., Verhulst, F.C., Burdorf, A., Jaddoe, V.W.V.K., Hofman, A., Moll, H.A., Verburg, B.O., Steegers, E.A.P., Mackenbach, J.P. & Raat, H. (2010). Employment status and the risk of pregnancy complications: the Generation R Study. Occupational and Environmental Medicine, 67, 387-394.
Jansen, P.W., Raat, H., Mackenbach, J.P., Jaddoe, V.W.V.K., Hofman, A., Oort, F.V.A. van, Verhulst, F.C. & Tiemeier, H.W.
(2010). National Origin and Behavioural Problems of Toddlers: The Role of Family Risk Factors and Maternal Immigration Characteristics. Journal of Abnormal Child Psychology, 38(8), 1151-1164.
Jong, J.C. de, Escher, J.C., Arends, L.R., Jaddoe, V.W.V.K., Hofman, A., Raat, H. & Moll, H.A. (2010). Infant nutritional factors and functional constipation in childhood: The Generation R Study. American Journal of Gastroenterology, 105, 940-945.
Jonge, L.L. de, Osch-Gevers, M. van, Geelhoed, J.J.M., Hofman, A., Steegers, E.A.P., Helbing, W.A. & Jaddoe, V.W.V.K.
(2010). Breastfeeding is not associated with left cardiac structures and blood pressure during the first two years of life. The Generation R Study. Early Human Development, 86(8), 463-468.
Kardys, I., Deckers, J.W., Stricker, B.H.C., Vletter, W.B., Hofman, A. & Witteman, J.C.M. (2010). Distribution of
echocardiographic parameters and their associations with cardiovascular risk factors in the Rotterdam Study. European Journal of Epidemiology, 25(7), 481-490.
Kerkhof, J.M., Meulenbelt, I., Carr, A, Gonzalez, A., Hart, D. t, Hofman, A., Kloppenburg, M, Lane, NE, Loughlin, J, Nevitt, MC, Pols, H.A.P., Rivadeneira, F., Slagboom, E.P., Spector, T.D., Stolk, L., Tsezou, A, Uitterlinden, A.G., Valdes, A.M. & Meurs, J.B.J. van (2010). Common genetic variation in the Estrogen Receptor Beta (ESR2) gene and osteoarthritis: results of a meta- analysis. BMC Medical Genetics, 11.
Kerkhof, J.M., Bierma-Zeinstra, S.M.A., Castano Betancourt, M.C., Maat, M.P.M. de, Hofman, A., Pols, H.A.P., Rivadeneira Ramirez, F., Witteman, J.C.M., Uitterlinden, A.G. & Meurs, J.B.J. van (2010). Serum C reactive protein levels and genetic variation in the CRP gene are not associated with the prevalence, incidence or progression of osteoarthritis independent of body mass index. Annals of the Rheumatic Diseases, 69(11), 1976-1982.
Kestenbaum, B, Glazer, NL, Kottgen, A, Felix, J.F., Hwang, SJ, Liu, YM, Lohman, K, Kritchevsky, SB, Hausman, DB, Petersen, AK, Gieger, C, Ried, JS, Meitinger, T, Strom, TM, Wichmann, HE, Campbell, H, Hayward, C, Rudan, I, Boer, I.H., Psaty, B.M., Rice, KM, Chen, YDI, Li, M., Arking, DE, Boerwinkle, E., Coresh, J, Yang, QO, Levy, D., Rooij, F.J.A. van, Dehghan, A., Rivadeneira, F., Uitterlinden, A.G., Hofman, A., Duijn, C.M. van, Shlipak, M.G., Kao, WHL, Witteman, J.C.M., Siscovick, D.S. &
Fox, CS (2010). Common Genetic Variants Associate with Serum Phosphorus Concentration. Journal of the American Society of Nephrology, 21(7), 1223-1232.
Kiiski, V, Vries, E. de, Flohil, S.C., Bijl, M.J., Hofman, A., Stricker, B.H.C. & Nijsten, T.E.C. (2010). Risk Factors for Single and Multiple Basal Cell Carcinomas. Archives of Dermatology, 146(8), 848-855.
Koek, W.N.H., Meurs, J.B.J. van, Eerden, B.C.J. van der, Rivadeneira, F., Zillikens, M.C., Hofman, A., Obermayer-Pietsch, B, Lips, P., Pols, H.A., Uitterlinden, A.G. & Leeuwen, J.P.T.M. van (2010). The T-13910C Polymorphism in the Lactase Phlorizin Hydrolase Gene Is Associated With Differences in Serum Calcium Levels and Calcium Intake. Journal of Bone and Mineral Research, 25(9), 1980-1987.
Kuil, W Altorf-van der, Engberink, MF, Rooij, F.J.A. van, Hofman, A., Veer, P. van 't, Witteman, J.C.M. & Geleijnse, J.M. (2010).
Dietary protein and risk of hypertension in a Dutch older population: the Rotterdam study. Journal of Hypertension, 28(12), 2394-2400.
Lau, L.M.L. de, Meurs, J.B.J. van, Uitterlinden, A.G., Smith, AD, Refsum, H., Johnston, C & Breteler, M.M.B. (2010). Genetic variation in homocysteine metabolism, cognition, and white matter lesions. Neurobiology of Aging, 31(11), 2020-2022.
Lebon, A., Moll, H.A., Tavakol, M., Wamel, W.J.B. van, Jaddoe, V.W.V.K., Hofman, A., Verbrugh, H.A. & Belkum, A. van (2010).
Correlation of bacterial colonization status between mother and child: the Generation R Study. Journal of Clinical Microbiology, 48(3), 960-962.
Leening, M.J.G., Elias-Smale, S.E., Felix, J.F., Kors, J.A., Deckers, J.W., Hofman, A., Stricker, B.H.C. & Witteman, J.C.M.
(2010). Unrecognised myocardial infarction and long-term risk of heart failure in the elderly: the Rotterdam Study. Heart, 96(18), 1458-1462.
Liu, F., Wollstein, A.D., Hysi, PG, Ankra-Badu, GA, Spector, T.D., Park, D, Larsson, M., Duffy, DL, Montgomery, GW, Mackey, DA, Walsh, S., Lao Grueso, O., Hofman, A., Rivadeneira Ramirez, F., Vingerling, J.R., Uitterlinden, A.G., Martin, NG,
Hammond, CJ, Kayser, M. & Zhu, G (2010). Digital Quantification of Human Eye Color Highlights Genetic Association of Three New Loci. PLoS Genetics, 6(5).
Liu, F., Pardo, LM, Schuur, M., Sanchez-Juan, P, Isaacs, A.J., Koning, I.V., Sleegers, K., Zorkoltseva, IV, Axenovich, T.I., Witteman, J.C.M., Janssens, A.C.J.W., Swieten, J.C. van, Aulchenko, Y.S., Oostra, B.A. & Duijn, C.M. van (2010). The apolipoprotein E gene and its age-specific effects on cognitive function. Neurobiology of Aging, 31(10), 1831-1833.
Lopez Leon, S., Aulchenko, Y.S., Tiemeier, H.W., Oostra, B.A., Duijn, C.M. van & Janssens, A.C.J.W. (2010). Shared genetic factors in the co-occurrence of symptoms of depression and cardiovascular risk factors. Journal of Affective Disorders, 122(3), 247-252.
Lorenz, MW, Bickel, H, Bots, M.L., Breteler, M.M.B., Catapano, AL, Desvarieux, M, Hedblad, B, Iglseder, B, Johnsen, SH, Juraska, M, Kiechl, S, Mathiesen, EB, Norata, GD, Grigore, L, Polak, J, Poppert, H, Rosvall, M, Rundek, T, Sacco, R.L., Sander, D, Sitzer, M, Steinmetz, H, Stensland, E, Willeit, J, Witteman, J.C.M., Yanez, D & Thompson, SG (2010). Individual progression of carotid intima media thickness as a surrogate for vascular risk (PROG-IMT): Rationale and design of a meta-analysis project.
American Heart Journal, 159(5), 730-U25.
Lubitz, SA, Sinner, MF, Lunetta, KL, Makino, S, Pfeufer, A, Rahman, R, Veltman, C.E., Barnard, J, Bis, JC, Danik, SP, Sonni, A, Shea, MA, Monte, F del, Perz, S, Muller, M., Peters, A., Greenberg, SM, Furie, KL, Noord, C. van, Boerwinkle, E., Stricker, B.H.C., Witteman, J.C.M., Smith, JD, Chung, MK, Heckbert, SR, Benjamin, EJ, Rosand, J, Arking, DE, Alonso, A., Kaab, S &
Ellinor, PT (2010). Independent Susceptibility Markers for Atrial Fibrillation on Chromosome 4q25. Circulation, 122(10), 976- U66.
Luijendijk, H.J., Tiemeier, H.W., Berg, J.F. van den, Bleumink, G.S., Hofman, A. & Stricker, B.H.C. (2010). Heart Failure and Incident Late-Life Depression. Journal of American Geriatrics Society, 58(8), 1441-1446.
Luijk, P.C.M., Saridjan, N.S., Tharner, A., Ijzendoorn, MH van, Bakermans-Kranenburg, MJ, Jaddoe, V.W.V.K., Hofman, A., Verhulst, F.C. & Tiemeier, H.W. (2010). Attachment, Depression, and Cortisol: Deviant Patterns in Insecure-Resistant and Disorganized Infants. Developmental Psychobiology, 52(5), 441-452.
Luijk, P.C.M., Velders, F.P., Tharner, A., IJzerdoorn, MH, Bakermans-Kranenburg, MJ, Jaddoe, V.W.V.K., Hofman, A., Verhulst, F.C. & Tiemeier, H.W. (2010). FKBP5 and resistant attachment predict cortisol reactivity in infants: Gene-environment
interaction. Psychoneuroendocrinology, 35(10), 1454-1461.
Maas, A.J.B.M., Mook-Kanamori, D.O., Ay, L., Steegers, E.A.P., Duijn, C.M. van, Hofman, A., Hokken-Koelega, A.C.S. &
Jaddoe, V.W.V.K. (2010). Insulin VNTR and IGF-1 promotor region polymorphisms are not associated with body composition in early childhood: The Generation R Study. Hormone Research, 73, 120-127.
Marroun El, H., Tiemeier, H.W., Steegers, E.A.P., Roos-Hesselink, J.W., Jaddoe, V.W.V.K., Hofman, A., Verhulst, F.C., Brink, W van den & Huizink, A.C. (2010). A prospective study on intrauterine cannabis exposure and fetal blood flow. Early Human Development, 86(4), 231-236.
Mattace Raso, F.U.S., Verwoert, G.C., Hofman, A. & Witteman, J.C.M. (2010). Inflammation and incident-isolated systolic hypertension in older adults: the Rotterdam study. Journal of Hypertension, 28(5), 892-895.
Meyer, TE, Verwoert, G.C., Hwang, SJ, Glazer, NL, Smith, AV, Rooij, F.J.A. van, Ehret, GB, Boerwinkle, E., Felix, J.F., Leak, TS, Harris, T.B., Yang, Q, Dehghan, A., Aspelund, T, Katz, R, Homuth, G., Kocher, T, Rettig, R, Ried, JS, Gieger, C, Prucha, H, Pfeufer, A, Meitinger, T, Coresh, J, Hofman, A., Sarnak, MJ, Chen, YDI, Uitterlinden, A.G., Chakravarti, A, Psaty, B.M., Duijn,
C.M. van, Kao, WHL, Witteman, J.C.M., Gudnason, V, Siscovick, D.S., Fox, CS & Kottgen, A (2010). Genome-Wide Association Studies of Serum Magnesium, Potassium, and Sodium Concentrations Identify Six Loci Influencing Serum Magnesium Levels.
PLoS Genetics, 6(8).
Mihaescu, R., Zitteren, M. van, Hoek, M. van der, Sijbrands, E.J.G., Uitterlinden, A.G., Witteman, J.C.M., Hofman, A., Hunink, M.G.M., Duijn, C.M. van & Janssens, A.C.J.W. (2010). Improvement of Risk Prediction by Genomic Profiling: Reclassification Measures Versus the Area Under the Receiver Operating Characteristic Curve. American Journal of Epidemiology, 172(3), 353- 361.
Mohangoo, A.D., Koning, H.J. de, Groen, E. de, Wouden, J.C. van der, Jaddoe, V.W.V.K., Moll, H.A., Hofman, A., Mackenbach, J.P., Jongste, J.C. de & Raat, H. (2010). A comparison of parent-reported wheezing of shortness of breath among infants as assessed bij questonnaire and physician-interview: The Generation R Study. Pediatric Pulmonology, 45, 500-507.
Mook-Kanamori, D.O., Steegers, E.A.P., Eilers, PH, Raat, H., Hofman, A. & Jaddoe, V.W.V.K. (2010). Risk Factors and Outcomes Associated With First-Trimester Fetal Growth Restriction. Jama - Journal of the American Medical Association, 303(6), 527-534.
Morrison, AC, Felix, J.F., Cupples, L.A., Glazer, NL, Loehr, LR, Dehghan, A., Demissie, S, Bis, JC, Rosamond, WD, Aulchenko, Y.S., Wang, YA, Haritunians, T, Folsom, A.R., Rivadeneira, F., Benjamin, EJ, Lumley, T, Couper, D, Stricker, B.H.C., O'Donnell, CJ, Rice, KM, Chang, PP, Hofman, A., Levy, D., Rotter, JI, Fox, ER, Uitterlinden, A.G., Wang, T.J., Psaty, B.M., Willerson, J.T., Duijn, C.M. van, Boerwinkle, E., Witteman, J.C.M., Vasan, RS & Smith, NL (2010). Genomic Variation Associated With Mortality Among Adults of European and African Ancestry With Heart Failure The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. Circulation-cardiovascular genetics, 3(3), 248-U64.
Newman, AB, Walter, S., Lunetta, KL, Garcia, ME, Slagboom, P.E., Christensen, K., Arnold, AM, Aspelund, T, Aulchenko, Y.S., Benjamin, EJ, Christiansen, L, D'Agostino, RB, Fitzpatrick, AL, Franceschini, N, Glazer, NL, Gudnason, V, Hofman, A., Kaplan, R, karasik, D., Kelly-Hayes, M, Kiel, DP, Launer, L.J., Marciante, KD, Massaro, JM, Miljkovic, I, Nalls, MA, Hernandez, D., Psaty, B.M., Rivadeneira, F., Rotter, J, Seshadri, S, Smith, AV, Taylor, KD, Tiemeier, H.W., Uh, HW, Uitterlinden, A.G., Vaupel, JW, Walston, J, Westendorp, R.G.J., Harris, T.B., Lumley, T, Duijn, C.M. van & Murabito, JM (2010). A Meta-analysis of Four Genome-Wide Association Studies of Survival to Age 90 Years or Older: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. Journals of Gerontology Series A-Biological Sciences and Medical Sciences, 65(5), 478-487.
Newson, R.S., Hek, K., Luijendijk, H.J., Hofman, A., Witteman, J.C.M. & Tiemeier, H.W. (2010). Atherosclerosis and Incident Depression in Late Life. Archives of General Psychiatry, 67(11), 1144-1151.
Newson, R.S., Witteman, J.C.M., Franco, OH, Stricker, B.H.C., Breteler, M.M.B., Hofman, A. & Tiemeier, H.W. (2010).
Predicting survival and morbidity-free survival to very old age. Age, 32(4), 521-534.
Noord, C. van, Sturkenboom, M.C.J.M., Straus, S.M.J.M., Hofman, A., Kors, J.A., Witteman, J.C.M. & Stricker, B.H.C. (2010).
Serum glucose and insulin are associated with QTc and RR intervals in nondiabetic elderly. European Journal of Endocrinology, 162(2), 241-248.
Noord, C. van, Dorr, M, Sturkenboom, M.C.J.M., Straus, S.M.J.M., Reffelmann, T, Felix, SB, Hofman, A., Kors, J.A., Haring, R, Jong, F.H. de, Nauck, M., Uitterlinden, A.G., Wallaschofski, H., Witteman, J.C.M., Volzke, H & Stricker, B.H.C. (2010). The association of serum testosterone levels and ventricular repolarization. European Journal of Epidemiology, 25(1), 21-28.
Odink, A.E., Lugt, A. van der, Hofman, A., Hunink, M.G.M., Breteler, M.M.B., Krestin, G.P. & Witteman, J.C.M. (2010). Risk factors for coronary, aortic arch and carotid calcification; The Rotterdam Study. Journal of Human Hypertension, 24(2), 86-92.
O'Seaghdha, CM, Yang, QO, Glazer, NL, Leak, TS, Dehghan, A., Smith, AV, Kao, WHL, Lohman, K, Hwang, SJ, Johnson, AD, Hofman, A., Uitterlinden, A.G., Chen, YDI, Brown, EM, Siscovick, D.S., Harris, T.B., Psaty, B.M., Coresh, J, Gudnason, V, Witteman, J.C.M., Liu, YM, Kestenbaum, BR, Fox, CS & Kottgen, A (2010). Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels. Human Molecular Genetics, 19(21), 4296-4303.
Pardo Silva, M.C., Njajou, OT, Alizadeh, B.Z., Hofman, A., Witteman, J.C.M., Duijn, C.M. van & Janssens, A.C.J.W. (2010).
HFE gene mutations increase the risk of coronary heart disease in women. European Journal of Epidemiology, 25(9), 643-649.
Pfeufer, A, Noord, C. van, Marciante, KD, Arking, DE, Larson, MG, Smith, AV, Tarasov, KV, Muller, M., Sotoodehnia, N, Sinner, MF, Verwoert, G.C., Li, M., Kao, WHL, Kottgen, A, Coresh, J, Bis, JC, Psaty, B.M., Rice, K, Rotter, JI, Rivadeneira, F., Hofman, A., Kors, J.A., Stricker, B.H.C., Uitterlinden, A.G., Duijn, C.M. van, Beckmann, BM, Sauter, W, Gieger, C, Lubitz, SA, Newton- Cheh, C, Wang, T.J., Magnani, JW, Schnabel, RB, Chung, MK, Barnard, J, Smith, JD, Wagoner, DR Van, Vasan, RS, Aspelund, T, Eiriksdottir, G, Harris, T.B., Launer, L.J., Najjar, SS, Lakatta, E, Schlessinger, D, Uda, M, Abecasis, GR, Muller- Myhsok, B, Ehret, GB, Boerwinkle, E., Chakravarti, A, Soliman, EZ, Lunetta, KL, Perz, S, Wichmann, HE, Meitinger, T, Levy, D., Gudnason, V, Ellinor, PT, Sanna, S, Kaab, S, Witteman, J.C.M., Alonso, A., Benjamin, EJ & Heckbert, SR (2010). Genome-wide association study of PR interval. Nature Genetics, 42(2), 153-U89.
Poels, M.M.F., Vernooij, M.W., Ikram, M.A., Hofman, A., Krestin, G.P., Lugt, A. van der & Breteler, M.M.B. (2010). Prevalence and Risk Factors of Cerebral Microbleeds An Update of the Rotterdam Scan Study. Stroke, 41(10), S103-S106.
Psaty, B.M. & Hofman, A. (2010). Genome-wide association studies and large-scale collaborations in epidemiology. European Journal of Epidemiology, 25(8), 525-529.
Ramdas, W.D., Koolwijk, L.M.E. van, Ikram, M.K., Jansonius, N.M., Jong, P.T.V.M. de, Bergen, A.A.B., Isaacs, A.J., Amin, N., Aulchenko, Y.S., Wolfs, R.C.W., Hofman, A., Rivadeneira, F., Oostra, B.A., Uitterlinden, A.G., Hysi, P, Hammond, CJ, Lemij, H.G., Vingerling, J.R., Klaver, C.C.W. & Duijn, C.M. van (2010). A Genome-Wide Association Study of Optic Disc Parameters.
PLoS Genetics, 6(6).
Reitz, C.H., Rooij, F.J.A. van, Soares, HD, Maat, M.P.M. de, Hofman, A., Witteman, J.C.M. & Breteler, M.M.B. (2010). Matrix metalloproteinase 3 haplotypes and plasma amyloid beta levels: The Rotterdam Study. Neurobiology of Aging, 31(4), 715-718.
Rodenburg, E.M., Visser, L.E., Danser, A.H.J., Hofman, A., Noord, C. van, Witteman, J.C.M., Uitterlinden, A.G. & Stricker, B.H.C. (2010). Genetic variance in CYP2C8 and increased risk of myocardial infarction. Pharmacogenetics Genomics, 20(7), 426-434.
Rossem, L. van, Silva, L.M., Hokken-Koelega, A., Arends, L.R., Moll, H.A., Jaddoe, V.W.V.K., Hofman, A., Mackenbach, J.P. &
Raat, H. (2010). Socioeconomic status is not inversely associated with overweight in preschool children. Journal of Pediatrics, 157(6), 929-935.
Roza, S.J., Batenburg-Eddes, T. van, Steegers, E.A.P., Jaddoe, V.W.V.K., Mackenbach, J.P., Hofman, A., Verhulst, F.C. &
Tiemeier, H.W. (2010). Maternal folic acid supplement use in early pregnancy and child behavioural problems: The Generation R Study. British Journal of Nutrition, 103(3), 445-452.
Ruiter, R. de, Visser, L.E., Eijgelsheim, M., Rodenburg, E.M., Hofman, A., Coebergh, J.W.W., Nijsten, T.E.C. & Stricker, B.H.C.
(2010). High-ceiling diuretics are associated with an increased risk of basal cell carcinoma in a population-based follow-up study. European Journal of Cancer, 46(13), 2467-2472.
Rutten, J.H.W., Mattace Raso, F.U.S., Steyerberg, E.W., Lindemans, J., Hofman, A., Wieberdink, R.G., Breteler, M.M.B., Witteman, J.C.M. & Meiracker, A.H. van den (2010). Amino-Terminal Pro-B-Type Natriuretic Peptide Improves Cardiovascular and Cerebrovascular Risk Prediction in the Population The Rotterdam Study. Hypertension, 55(3), 785-791.
Rutten, J.H.W., Mattace Raso, F.U.S., Verwoert, G.C., Lindemans, J., Hofman, A., Witteman, J.C.M. & Meiracker, A.H. van den (2010). Arterial stiffness as determinant of increased amino terminal pro-B-type natriuretic peptide levels in individuals with and without cardiovascular disease - the Rotterdam Study. Journal of Hypertension, 28(10), 2061-2067.
Saridjan, N.S., Huizink, A.C., Koetsier, J.A., Jaddoe, V.W.V.K., Mackenbach, J.P., Hofman, A., Kirschbaum, C, Verhulst, F.C. &
Tiemeier, H.W. (2010). Do social disadvantage and early family adversity affect the diurnal cortisol rhythm in infants? The Generation R Study. Hormones & Behavior, 57(2), 247-254.
Schepper, E.I.T. de, Damen, J., Meurs, J.B.J. van, Ginai, A.Z., Popham, M, Hofman, A., Koes, B.W. & Bierma-Zeinstra, S.M.A.
(2010). The Association Between Lumbar Disc Degeneration and Low Back Pain The Influence of Age, Gender, and Individual Radiographic Features. Spine, 35(5), 531-536.
Schnabel, RB, Baumert, J., Barbalic, M, Dupuis, J, Ellinor, PT, Durda, P, Dehghan, A., Bis, JC, Illig, T, Morrison, AC, Jenny, NS, Keaney, JF, Gieger, C, Tilley, C, Yamamoto, JF, Khuseyinova, N, Heiss, G, Doyle, M, Blankenberg, S, Herder, C. den, Walston, JD, Zhu, YY, Vasan, RS, Klopp, N, Boerwinkle, E., Larson, MG, Psaty, B.M., Peters, A., Ballantyne, C.M., Witteman, J.C.M., Hoogeveen, RC, Benjamin, EJ, Koenig, W. & Tracy, RP (2010). Duffy antigen receptor for chemokines (Darc) polymorphism regulates circulating concentrations of monocyte chemoattractant protein-1 and other inflammatory mediators. Blood, 115(26), 5289-5299.
Schrijvers, E.M.C., Witteman, J.C.M., Sijbrands, E.J.G., Hofman, A., Koudstaal, P.J. & Breteler, M.M.B. (2010). Insulin metabolism and the risk of Alzheimer disease The Rotterdam Study. Neurology, 75(22), 1982-1987.
Schuur, M., Henneman, P., Swieten, J.C. van, Zillikens, M.C., Koning, I. de, Janssens, A.C.J.W., Witteman, J.C.M., Aulchenko, Y.S., Frants, R.R., Oostra, B.A., Dijk, KW van & Duijn, C.M. van (2010). Insulin-resistance and metabolic syndrome are related to executive function in women in a large family-based study. European Journal of Epidemiology, 25(8), 561-568.
Seshadri, S, Fitzpatrick, AL, Ikram, M.A., DeStefano, AL, Gudnason, V, Boada, M, Bis, JC, Smith, AV, Carassquillo, MM, Lambert, JC, Harold, D, Schrijvers, E.M.C., Ramirez-Lorca, R, Debette, S, Longstreth, W.T., Janssens, A.C.J.W., Pankratz, VS, Dartigues, J.F., Hollingworth, P, Aspelund, T, Hernandez, I, Beiser, A, Kuller, LH, Koudstaal, P.J., Dickson, DW, Tzourio, C., Abraham, R, Antunez, C, Du, YC, Rotter, JI, Aulchenko, Y.S., Harris, T.B., Petersen, R.C., Berr, C, Owen, M.J., Lopez-Arrieta, J, Varadarajan, BN, Becker, JT, Rivadeneira, F., Nalls, MA, Graff-Radford, NR, Campion, D, Auerbach, S, Rice, K, Hofman, A., Jonsson, PV, Schmidt, H., Lathrop, M, Mosley, TH, Psaty, B.M., Uitterlinden, A.G., Farrer, L.A., Lumley, T, Ruiz, A., Williams, J., Amouyel, P, Younkin, SG, Wolf, PA, Launer, L.J., Lopez, OL, Duijn, C.M. van & Breteler, M.M.B. (2010). Genome-wide Analysis of Genetic Loci Associated With Alzheimer Disease. Jama - Journal of the American Medical Association, 303(18), 1832-1840.
Siemes, C., Visser, L.E., Jong, F.H. de, Coebergh, J.W.W., Uitterlinden, A.G., Hofman, A., Stricker, B.H.C. & Schaik, R.H.N. van (2010). Cytochrome P450 3A gene variation, steroid hormone serum levels and prostate cancer-The Rotterdam Study. Steroids, 75(12), 1024-1032.
Silva, L.M., Jansen, P.W., Steegers, E.A.P., Jaddoe, V.W.V.K., Arends, L.R., Tiemeier, H.W., Verhulst, F.C., Moll, H.A., Hofman, A., Mackenbach, J.P. & Raat, H. (2010). Mother's educational level and fetal growth: the genesis of health inequalities.
International Journal of Epidemiology, 39, 1250-1261.
Smith, NL, Felix, J.F., Morrison, AC, Demissie, S, Glazer, NL, Loehr, LR, Cupples, L.A., Dehghan, A., Lumley, T, Rosamond, WD, Lieb, W, Rivadeneira, F., Bis, JC, Folsom, A.R., Benjamin, E, Aulchenko, Y.S., Haritunians, T, Couper, D, Murabito, J, Wang, YA, Stricker, B.H.C., Gottdiener, JS, Chang, PP, Wang, T.J., Rice, KM, Hofman, A., Heckbert, SR, Fox, ER, O'Donnell, CJ, Uitterlinden, A.G., Rotter, JI, Willerson, J.T., Levy, D., Duijn, C.M. van, Psaty, B.M., Witteman, J.C.M., Boerwinkle, E. &
Vasan, RS (2010). Association of Genome-Wide Variation With the Risk of Incident Heart Failure in Adults of European and African Ancestry A Prospective Meta-Analysis From the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium. Circulation-cardiovascular genetics, 3(3), 256-U79.
Smith, NL, Chen, MH, Dehghan, A., Strachan, DP, Basu, S., Soranzo, N, Hayward, C, Rudan, I, Sabater-Lleal, M, Bis, JC, Maat, M.P.M. de, Rumley, A, Kong, XX, Yang, Q, Williams, FMK, Vitart, V, Campbell, H, Malarstig, A, Wiggins, KL, Duijn, C.M.
van, McArdle, WL, Pankow, JS, Johnson, AD, Silveira, A, McKnight, B, Uitterlinden, A.G., Aleksic, N, Meigs, JB, Peters, A., Koenig, W., Cushman, M., Kathiresan, S, Rotter, JI, Bovill, EG, Hofman, A., Boerwinkle, E., Tofler, GH, Peden, JF, Psaty, B.M., Leebeek, F.W.G., Folsom, A.R., Larson, MG, Spector, T.D., Wright, AF, Wilson, JF, Hamsten, A., Lumley, T, Witteman, J.C.M., Tang, WH & O'Donnell, CJ (2010). Novel Associations of Multiple Genetic Loci With Plasma Levels of Factor VII, Factor VIII, and von Willebrand Factor The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium.
Circulation, 121(12), 1382-U45.
Sofat, R, Hingorani, AD, Smeeth, L, Humphries, SE, Talmud, P.J., Cooper, J, Shah, T, Sandhu, MS, Ricketts, SL, Boekholdt, S.M., Wareham, N, Khaw, KT, Kumari, M, Kivimaki, M, Marmot, M, Asselbergs, F.W., Harst, P. van der, Dullaart, R.P.F., Navis, G, Veldhuisen, D.J., Gilst, W.H. van, Thompson, J.F., McCaskie, P, Palmer, LJ, Arca, M, Quagliarini, F, Gaudio, C, Cambien, F., Nicaud, V., Poirer, O, Gudnason, V, Isaacs, A.J., Witteman, J.C.M., Duijn, C.M. van, Pencina, M, Vasan, RS, D'Agostino, RB, Ordovas, J, Li, TY, Kakko, S, Kauma, H, Savolainen, MJ, Kesaniemi, YA, Sandhofer, A, Paulweber, B, Sorli, JV, Goto, A, Yokoyama, S, Okumura, K, Horne, BD, Packard, C, Freeman, D., Ford, I, Sattar, N, McCormack, V, Lawlor, DA, Ebrahim, S, Smith, G.D., Kastelein, J.J.P., Deanfield, J. & Casas, JP (2010). Separating the Mechanism-Based and Off-Target Actions of Cholesteryl Ester Transfer Protein Inhibitors With CETP Gene Polymorphisms. Circulation, 121(1), 52-62.
Solouki, A., Verhoeven, V.J.M., Duijn, C.M. van, Verkerk, A.J.M.H., Ikram, M.K., Hysi, PG, Despriet, D.D.G., Koolwijk, L.M.E.
van, Ho, L., Ramdas, W.D., Czudowska, M.A., Kuijpers, R.W.A.M., Amin, N., Struchalin, M, Aulchenko, Y.S., Rij, G. van, Riemslag, FCC, Young, TL, Mackey, DA, Spector, T.D., Gorgels, T.G.M.F., Willemse-Assink, JJM, Isaacs, A.J., Kramer, R, Swagemakers, S.M.A., Bergen, A.A.B., Oosterhout, A.A.L.J. van, Oostra, B.A., Rivadeneira, F., Uitterlinden, A.G., Hofman, A., Jong, P.T.V.M. de, Hammond, CJ, Vingerling, J.R. & Klaver, C.C.W. (2010). A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14. Nature Genetics, 42(10), 897-901.
Sotoodehnia, N, Isaacs, A.J., Bakker, PIW de, Dorr, M, Newton-Cheh, C, Nolte, I.M., Harst, P. van der, Muller, M., Eijgelsheim, M., Alonso, A., Hicks, AA, Padmanabhan, S, Hayward, C, Smith, AV, Polasek, O, Giovannone, S, Fu, JY, Magnani, JW, Marciante, KD, Pfeufer, A, Gharib, SA, Teumer, A, Li, M., Bis, JC, Rivadeneira, F., Aspelund, T, Kottgen, A, Johnson, T, Rice, K, Sie, M.P.S., Wang, YA, Klopp, N, Fuchsberger, C, Wild, SH, Leach, IM, Estrada, K, Volker, U, Wright, AF, Asselbergs, F.W., Qu, JX, Chakravarti, A, Sinner, MF, Kors, J.A., Petersmann, A, Harris, T.B., Soliman, EZ, Munroe, PB, Psaty, B.M., Oostra, B.A., Cupples, L.A., Perz, S, Boer, R.A. de, Uitterlinden, A.G., Volzke, H, Spector, T.D., Liu, FY, Boerwinkle, E., Dominiczak, AF, Rotter, JI, Herpen, G. van, Levy, D., Wichmann, HE, Gilst, W.H. van, Witteman, J.C.M., Kroemer, HK, Kao, WHL, Heckbert, SR, Meitinger, T, Hofman, A., Campbell, H, Folsom, A.R., Veldhuisen, D.J., Schwienbacher, C, O'Donnell, CJ, Volpato, CB, Caulfield, MJ, Connell, JM, Launer, L, Lu, XW, Franke, L, Fehrmann, RSN, Meerman, GT, Groen, H.J.M., Weersma, RK, Berg, L.H. van den, Wijmenga, C., Ophoff, R.A., Navis, G, Rudan, I, Snieder, H, Wilson, JF, Pramstaller, P.P., Siscovick, D.S., Wang, T.J., Gudnason, V, Duijn, C.M. van, Felix, SB, Fishman, GI & Jamshidi, Y (2010). Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Nature Genetics, 42(12), 1068-1076.
Struchalin, M.V., Dehghan, A., Witteman, J.C.M., Duijn, C.M. van & Aulchenko, Y.S. (2010). Variance heterogeneity analysis for detection of potentially interacting genetic loci: method and its limitations. Bmc Genetics, 11.
Thorgeirsson, TE, Gudbjartsson, DF, Surakka, I, Vink, J.M., Amin, N., Geller, F, Sulem, P, Rafnar, T, Esko, T, Walter, S., Gieger, C, Rawal, R, Mangino, M, Prokopenko, I, Magi, R, Keskitalo, K, Gudjonsdottir, IH, Gretarsdottir, S, Stefansson, H, Thompson, JR, Aulchenko, Y.S., Nelis, M, Aben, KK, Heijer, M. den, Dirksen, A., Ashraf, H, Soranzo, N, Valdes, A.M., Steves, C, Uitterlinden, A.G., Hofman, A., Tonjes, A, Kovacs, P, Hottenga, J.J., Willemsen, G, Vogelzangs, N, Doring, A, Dahmen, N, Nitz, B, Pergadia, ML, Saez, B, Diego, V De, Lezcano, V, Garcia-Prats, MD, Ripatti, S, Perola, M, Kettunen, J, Hartikainen, AL, Pouta, A, Laitinen, J, Isohanni, M, Huei-Yi, S, Allen, M, Krestyaninova, M, Hall, AS, Jones, GT, Rij, AM van, Mueller, T., Dieplinger, B, Haltmayer, M, Jonsson, S, Matthiasson, SE, Oskarsson, H, Tyrfingsson, T, Kiemeney, LA, Mayordomo, JI, Lindholt, JS, Pedersen, J.H., Franklin, WA, Wolf, H., Montgomery, GW, Heath, AC, Martin, NG, Madden, PAF, Giegling, I, Rujescu, D, Jarvelin, MR, Salomaa, V, Stumvoll, M., Spector, T.D., Wichmann, HE, Metspalu, A, Samani, NJ, Penninx, BW, Oostra, B.A., Boomsma, D.I., Tiemeier, H.W., Duijn, C.M. van, Kaprio, J, Gulcher, JR, McCarthy, MI, Peltonen, L.,
Thorsteinsdottir, U & Stefansson, K (2010). Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.
Nature Genetics, 42(5), 448-U135.
Tripepi, G, Mattace Raso, F.U.S., Rapisarda, F, Stancanelli, B, Malatino, L, Witteman, J.C.M., Zoccali, C & Mallamaci, F (2010).
Traditional and nontraditional risk factors as predictors of cerebrovascular events in patients with end stage renal disease.
Journal of Hypertension, 28(12), 2468-2474.
Vegt, E.J.M. van der, Ende, J. van der, Huizink, A.C., Verhulst, F.C. & Tiemeier, H.W. (2010). Childhood Adversity Modifies the Relationship Between Anxiety Disorders and Cortisol Secretion. Biological Psychiatry, 68(11), 1048-1054.
Vergeer, M, Boekholdt, S.M., Sandhu, MS, Ricketts, SL, Wareham, NJ, Brown, MJ, Faire, U de, Leander, K, Gigante, B, Kavousi, M., Hofman, A., Uitterlinden, A.G., Duijn, C.M. van, Witteman, J.C.M., Jukema, J.W., Schadt, EE, Schoot, E. van der, Kastelein, J.J.P., Khaw, KT, Dullaart, R.P.F., Tol, A. van, Trip, M.D. & Dallinga-Thie, G.M. (2010). Genetic Variation at the Phospholipid Transfer Protein Locus Affects Its Activity and High-Density Lipoprotein Size and Is a Novel Marker of Cardiovascular Disease Susceptibility. Circulation, 122(5), 470-477.
Verhaegh, S.J.C., Lebon, A., Saarloos, J.A., Verbrugh, H.A., Jaddoe, V.W.V.K., Hofman, A., Hays, J.P., Moll, H.A. & Belkum, A.
van (2010). Determinants of Moraxella catarrhalis colonization in healthy Dutch children during the first 14 months of life. Clinical Microbiology and Infection, 16(7), 992-997.
Verkaik, N.J., Lebon, A., Vogel, C.P. de, Hooijkaas, H., Verbrugh, H.A., Jaddoe, V.W.V.K., Hofman, A., Moll, H.A., Belkum, A.
van & Wamel, W.J.B. van (2010). Induction of antibodies by Staphylococcus aureus nasal colonization in young children.
Clinical Microbiology and Infection, 16(8), 1312-1317.
Visser, A.M., Jaddoe, V.W.V.K., Hofman, A., Moll, H.A., Steegers, E.A.P., Tiemeier, H.W., Raat, H., Breteler, M.M.B. & Arts, W.F.M. (2010). Fetal Growth Retardation and Risk of Febrile Seizures. Pediatrics, 126(4), E919-E925.
Visser, A.M., Jaddoe, V.W.V.K., Arends, L.R., Tiemeier, H.W., Hofman, A., Moll, H.A., Steegers, E.A.P., Breteler, M.M.B. & Arts, W.F.M. (2010). Paroxysmal disorders in infancy and their risk factors in a population-based cohort: the Generation R Study.
Developmental Medicine & Child Neurology, 52(11), 1014-1020.
Wang, T.J., Zhang, F., Richards, JB, Kestenbaum, B, Meurs, J.B.J. van, Berry, D, Kiel, DP, Streeten, EA, Ohlsson, C, Koller, DL, Peltonen, L., Cooper, JD, O'Reilly, PF, Houston, DK, Glazer, NL, Vandenput, L, Peacock, M., Shi, J, Rivadeneira, F., McCarthy, MI, Anneli, P, Boer, I.H., Mangino, M, Kato, B, Smyth, DJ, Booth, SL, Jacques, PF, Burke, GL, Goodarzi, M, Cheung, C., Wolf, M. van der, Rice, K, Goltzman, D, Hidiroglou, N, Ladouceur, M, Wareham, NJ, Hocking, LJ, Hart, D. t, Arden, NK, Cooper, C., Malik, S, Fraser, WD, Hartikainen, AL, Zhai, GJ, Macdonald, HM, Forouhi, NG, Loos, RJF, Reid, D.M., Hakim, A., Dennison, E, Liu, YM, Power, C, Stevens, HE, Jaana, L, Vasan, RS, Soranzo, N, Bojunga, J, Psaty, B.M., Lorentzon, M, Foroud, T., Harris, T.B., Hofman, A., Jonsson, JO, Cauley, J.A., Uitterlinden, A.G., Gibson, Q, Jarvelin, MR, karasik, D., Siscovick, D.S., Econs, M.J., Kritchevsky, SB, Florez, JC, Todd, JA, Dupuis, J, Hypponen, E & Spector, T.D. (2010). Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet (UK), 376(9736), 180-188.
Waterworth, D.M., Ricketts, SL, Song, KJ, Chen, L., Zhao, JH, Ripatti, S, Aulchenko, Y.S., Zhang, WH, Yuan, X, Lim, N, Luan, JA, Ashford, S, Wheeler, E, Young, EH, Hadley, D, Thompson, JR, Braund, PS, Johnson, T, Struchalin, M, Surakka, I, Luben, R, Khaw, KT, Rodwell, SA, Loos, RJF, Boekholdt, S.M., Inouye, M, Deloukas, P, Elliott, P, Schlessinger, D, Sanna, S, Scuteri, A, Jackson, A, Mohlke, KL, Tuomilehto, J, Roberts, R., Stewart, A, Kesaniemi, YA, Mahley, RW, Grundy, S.M., McArdle, W, Cardon, L., Waeber, G, Vollenweider, P, Chambers, JC, Boehnke, M, Abecasis, GR, Salomaa, V, Jarvelin, MR, Ruokonen, A, Barroso, I, Epstein, SE, Hakonarson, HH, Rader, DJ, Reilly, MP, Witteman, J.C.M., Hall, AS, Samani, NJ, Strachan, DP, Barter, P., Duijn, C.M. van, Kooner, JS, Peltonen, L., Wareham, NJ, McPherson, R, Mooser, V & Sandhu, MS (2010). Genetic Variants Influencing Circulating Lipid Levels and Risk of Coronary Artery Disease. Arteriosclerosis Thrombosis & Vascular Biology, 30(11), 2264-U566.
Wieberdink, R.G., Schie, M.C. van, Koudstaal, P.J., Hofman, A., Witteman, J.C.M., Maat, M.P.M. de, Leebeek, F.W.G. &
Breteler, M.M.B. (2010). High von Willebrand Factor Levels Increase the Risk of Stroke The Rotterdam Study. Stroke, 41(10), 2151-2156.
Wieberdink, R.G., Ikram, M.K., Koudstaal, P.J., Hofman, A., Vingerling, J.R. & Breteler, M.M.B. (2010). Retinal Vascular Calibers and the Risk of Intracerebral Hemorrhage and Cerebral Infarction The Rotterdam Study. Stroke, 41(12), 2757-2761.
Wolff, N.J., Darlington, A.S., Hunfeld, J.A.M., Verhulst, F.C., Jaddoe, V.W.V.K., Hofman, A., Passchier, J. & Tiemeier, H.W.
(2010). Determinants of Somatic Complaints in 18-month-old Children: The Generation R Study. Journal of Pediatric Psychology, 35(3), 306-316.
Zillikens, M.C., Meurs, J.B.J. van, Rivadeneira, F., Hofman, A., Oostra, B.A., Sijbrands, E.J.G., Witteman, J.C.M., Pols, H.A.P., Duijn, C.M. van & Uitterlinden, A.G. (2010). Interactions between dietary vitamin E intake and SIRT1 genetic variation influence body mass index. American Journal of Clinical Nutrition, 91(5), 1387-1393.
