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In vitro activities of novel 4-HPR derivatives on a panel of rhabdoid and other tumor cell lines

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Figure 1 Chemical structures of ATRA, 4-HPR, and 4-HPR derivatives and peptidomimetics: A
Figure 2 Inhibition of RT cell growth by 4-HPR and itsderivatives and peptidomimetics: Survival curves of MON (A),G401 (B) and A204 (C) cells treated for three days with increasingconcentrations of ATRA, 4-HPR, the most active halogen substitutedderivative of 4-HPR (5h and 5j) and peptidomimetic compounds(11a, 11c and 11d).
Table 1 IC50 values for ATRA, 4-HPR, and derivatives on various tumor cell lines
Figure 4 Induction of cell death by 4-HPR and its derivatives10and peptidomimetics: A-C
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