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Inflammation leads to distinct populations of extracellular vesicles from microglia

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Figure

Fig. 1 Characterization of microglia-derived extracellular vesicles. Microglia (BV2) were activated by treatment with LPS for 12 h before25 times more than control to obtain similar concentration of EVs to demonstrate size distribution
Fig. 2 Increased levels of proinflammatroy cytokines in microglia-derived extracellular vesicles upon LPS activation
Fig. 3 Reduction in the number of microglia-derived extracellular vesicles by inhibition of TNF signaling pathway
Fig. 4 Systemic inflammation in mice after focal cerebral ischemia. The levels of cytokines in serum were analyzed by multiplex ELISA from WTANOVA followed by TukeypMCAO.and TNF-KO mice without manipulation and 1 day after focal cerebral ischemia
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