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A CTNNA3 compound heterozygous deletion implicates a role for αT-catenin in susceptibility to autism spectrum disorder

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Academic year: 2020

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Figure

Figure 1 (See legend on next page.)
Figure 2 Further characterisation ofdeletion breakpoints, respectively: only the allele with the deletion can be amplified and visualized as a band of 301 bp in the father, in the probandand the unaffected sister, and as a band of 949 bp in the mother and
Figure 3 Pedigree of four ASD families carrying CTNNA3 exonic deletions. Black filling indicates ASD diagnosis.
Figure 4 Expression analysis ofcortex ctnna3 in mouse brain. Western blot analysis of αT-catenin and αN-catenin in mouse hippocampus (A) and (B) at different developmental stages (from P0 to P90)

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