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Mass spectrometry imaging as a tool for evaluating the pulmonary distribution of exogenous surfactant in premature lambs

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Figure

Fig. 1 Workflow of MSI analysis. The right lungs of lambs were cut into four pieces of approximately 3 cm (a) and the lower face of the third piece was cryo-sectioned and thaw-mounted onto a conductive glass slide
Fig. 2 Violin plot showing the intensity distribution of SP-B analog and SP-C analog (measured as the SP-C analog-Na + ion) in surfactant-treated (Treated, SF) and in untreated control (Ctrl, C) animals
Table 1 Fetal status and physiological measurements after 15 min of mechanical ventilation prior to surfactant treatment Group BW (kg) Fetal (cord blood) Values after 15 min of mechanical ventilation
Fig. 4 Time course of the physiological parameters for each animal included in the study
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