Genetic Testing Common ICD-10-CM Codes

Diagnosis

Code

Diagnosis (sign or symptom)

R76.9 Abnormal immunological finding in serum, unspecified R94.5 Abnormal results of liver function studies

D68.51 Activated protein C resistance R1Ø.Ø Acute abdomen

I82.4Ø2 Acute embolism and thrombosis of unspecified deep veins of left lower extremity

I82.4Ø3 Acute embolism and thrombosis of unspecified deep veins of lower extremity, bilateral

I82.4Ø1 Acute embolism and thrombosis of unspecified deep veins of right lower extremity

I82.4Ø9 Acute embolism and thrombosis of unspecified deep veins of unspecified lower extremity

B16.9 Acute hepatitis B without delta-agent and without hepatic coma

B17.1Ø Acute hepatitis C without hepatic coma N76.Ø Acute vaginitis

N76.2 Acute vulvitis

M81.Ø Age-related osteoporosis without current pathological fracture

N91.2 Amenorrhea, unspecified D64.9 Anemia, unspecified D68.61 Antiphospholipid syndrome

Z21 Asymptomatic human immunodeficiency virus [HIV] infection status

R87.61Ø Atypical squamous cells of undetermined significance on cytologic smear of cervix [ASC-US]

R31.1 Benign essential microscopic hematuria Z22.51 Carrier of viral hepatitis B

Z22.52 Carrier of viral hepatitis C

R87.81Ø Cervical high-risk human papillomavirus [HPV] DNA test positive

See

Attachment Chromosomal abnormality in fetus, affecting _{management of mother, antepartum}

C91.1Ø Chronic lymphocytic leukemia of B-cell type not having achieved remission

C92.1Ø Chronic myeloid leukemia, BCR/ABL-positive, not having achieved remission

B18.1 Chronic viral hepatitis B without delta-agent B18.2 Chronic viral hepatitis C

D68.9 Coagulation defect, unspecified

Z2Ø.6 Contact with and (suspected) exposure to human immunodeficiency virus [HIV]

Z2Ø.2 Contact with and (suspected) exposure to infections with a predominantly sexual mode of transmission

Z2Ø.828 Contact with and (suspected) exposure to other viral communicable diseases

Z2Ø.5 Contact with and (suspected) exposure to viral hepatitis

Diagnosis

Code

Diagnosis (sign or symptom)

D72.819 Decreased white blood cell count, unspecified E66.1 Drug-induced obesity

R97.2 Elevated prostate specific antigen [PSA] D72.829 Elevated white blood cell count, unspecified Z36 Encounter for antenatal screening of mother

ZØ9 Encounter for follow-up examination after completed treatment for conditions other than malignant neoplasm ZØØ.Ø1 Encounter for general adult medical examination with

abnormal findings

ZØØ.ØØ Encounter for general adult medical examination without abnormal findings

ZØ1.411 Encounter for gynecological examination (general) (routine) with abnormal findings

ZØ1.419 Encounter for gynecological examination (general) (routine) without abnormal findings

Z13.71 Encounter for nonprocreative screening for genetic disease carrier status

Z3Ø.Ø9 Encounter for other general counseling and advice on contraception

Z31.438 Encounter for other genetic testing of female for procreative management

Z31.49 Encounter for other procreative investigation and testing Z13.79 Encounter for other screening for genetic and

chromosomal anomalies

Z32.Ø1 Encounter for pregnancy test, result positive Z39.2 Encounter for routine postpartum follow-up Z13.1 Encounter for screening for diabetes mellitus

Z11.4 Encounter for screening for human immunodeficiency virus [HIV]

Z11.51 Encounter for screening for human papillomavirus (HPV) Z11.3 Encounter for screening for infections with a

predominantly sexual mode of transmission Z11.9 Encounter for screening for infectious and parasitic

diseases, unspecified

Z12.4 Encounter for screening for malignant neoplasm of cervix

Z12.5 Encounter for screening for malignant neoplasm of prostate

Z13.89 Encounter for screening for other disorder

Z11.8 Encounter for screening for other infectious and parasitic diseases

Z13.228 Encounter for screening for other metabolic disorders Z13.29 Encounter for screening for other suspected endocrine

disorder

Z11.59 Encounter for screening for other viral diseases

Z34.Ø1 Encounter for supervision of normal first pregnancy, first trimester

Genetic Testing

Common ICD-10-CM Codes

The ICD-10-CM codes listed below are commonly associated with genetic testing, including cytogenetics, biochemical, and molecular genetics, were selected based on the reporting frequency to LabCorp of their ICD-9-CM counterparts. Code descriptions were taken from the official code set issued by the US Department of Health and Human Services and are scheduled to be implemented October 1, 2015. Depending on the nature of your practice, this list may be a useful reference tool; however, it is not a complete list. Please refer to an ICD-10-CM manual for a complete listing. The ultimate responsibility for the provision of correct diagnosis code(s) is with the ordering physician. The ordering physician must always determine, for the specific date of service, the appropriate diagnosis code(s) based on the patient’s signs and symptoms. ICD-CM codes in effect at the time of service are required by third-party payors to confirm the medical necessity of the test(s) and/or profile(s) ordered. Physicians are asked to submit all medically appropriate ICD-CM codes when ordering laboratory testing.

LabCorp’s provision of this information as a customer service does not suggest and is not meant to suggest that any of these codes should or should not be used on any given occasion. LabCorp makes no recommendation regarding the use of any particular diagnosis code(s). Diagnosis information should be reflected in the patient’s medical record.

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Diagnosis

Code

Diagnosis (sign or symptom)

Z34.-2 Encounter for supervision of normal first pregnancy, second trimester

Z34.Ø3 Encounter for supervision of normal first pregnancy, third trimester

Z34.ØØ Encounter for supervision of normal first pregnancy, unspecified trimester

Z31.43Ø Encounter of female for testing for genetic disease carrier status for procreative management

I1Ø Essential (primary) hypertension R35.Ø Frequency of micturition

K21.9 Gastro-esophageal reflux disease without esophagitis R31.9 Hematuria, unspecified

K74.Ø Hepatic fibrosis

Z72.53 High-risk bisexual behavior Z72.51 High-risk heterosexual behavior Z72.52 High-risk homosexual behavior

B2Ø Human immunodeficiency virus [HIV] disease R73.9 Hyperglycemia, unspecified

E78.5 Hyperlipidemia, unspecified EØ3.9 Hypothyroidism, unspecified D5Ø.9 Iron deficiency anemia, unspecified N92.6 Irregular menstruation, unspecified

Z79.3 Long-term (current) use of hormonal contraceptives Z79.891 Long-term (current) use of opiate analgesic

R87.612 Low-grade squamous intraepithelial lesion on cytologic smear of cervix [LGSIL]

D68.62 Lupus anticoagulant syndrome

C91.9Ø Lymphoid leukemia, unspecified not having achieved remission

F32.9 Major depressive disorder, single episode, unspecified C61 Malignant neoplasm of prostate

E78.2 Mixed hyperlipidemia

R53.Ø Neoplastic (malignant) related fatigue

R74.Ø Nonspecific elevation of levels of transaminase and lactic acid dehydrogenase [LDH]

D53.9 Nutritional anemia, unspecified E66.9 Obesity, unspecified

See Attachment

Other abnormal findings of blood chemistry R73.Ø9 Other abnormal glucose

K74.69 Other cirrhosis of liver R53.83 Other fatigue

R68.89 Other general symptoms and signs E78.4 Other hyperlipidemia

See

Attachment Other known or suspected fetal abnormality, not _{elsewhere classified, affecting management of mother,} antepartum condition or complication

Z79.899 Other long-term (current) drug therapy R53.81 Other malaise

See

Attachment Other malignant lymphomas, unspecified site, _{extranodal and solid organ sites} R31.2 Other microscopic hematuria

E66.8 Other obesity

E66.Ø9 Other obesity due to excess calories D68.59 Other primary thrombophilia

I26.Ø9 Other pulmonary embolism with acute cor pulmonale

I26.99 Other pulmonary embolism without acute cor pulmonale

R76.8 Other specified abnormal immunological findings in serum

D68.8 Other specified coagulation defects

Diagnosis

Code

Diagnosis (sign or symptom)

E13.9 Other specified diabetes mellitus without complications D72.89 Other specified disorders of white blood cells

N92.5 Other specified irregular menstruation

B97.7 Papillomavirus as the cause of diseases classified elsewhere

D45 Polycythemia vera G93.3 Postviral fatigue syndrome Z33.1 Pregnant state, incidental N91.Ø Primary amenorrhea D68.52 Prothrombin gene mutation E78.Ø Pure hypercholesterolemia R76.Ø Raised antibody titer N96 Recurrent pregnancy loss N91.1 Secondary amenorrhea N76.1 Subacute and chronic vaginitis N76.3 Subacute and chronic vulvitis

OØ9.521 Supervision of elderly multigravida, first trimester OØ9.522 Supervision of elderly multigravida, second trimester OØ9.523 Supervision of elderly multigravida, third trimester OØ9.529 Supervision of elderly multigravida, unspecified trimester OØ9.91 Supervision of high-risk pregnancy, unspecified, first

trimester

OØ9.92 Supervision of high-risk pregnancy, unspecified, second trimester

OØ9.93 Supervision of high-risk pregnancy, unspecified, third trimester

OØ9.9Ø Supervision of high-risk pregnancy, unspecified, unspecified trimester

See

Attachment Supervision of other high-risk pregnancy See

Attachment Supervision of other normal pregnancy A53.9 Syphilis, unspecified

E29.1 Testicular hypofunction D69.6 Thrombocytopenia, unspecified See

Attachment Tobacco use disorder

E11.65 Type 2 diabetes mellitus with hyperglycemia E11.9 Type 2 diabetes mellitus without complications R1Ø.9 Unspecified abdominal pain

R87.619 Unspecified abnormal cytological findings in specimens from cervix uteri

K74.6Ø Unspecified cirrhosis of liver See

Attachment Unspecified hepatitis

B19.1Ø Unspecified viral hepatitis B without hepatic coma B19.2Ø Unspecified viral hepatitis C without hepatic coma N39.Ø Urinary tract infection, site not specified

E55.9 Vitamin D deficiency, unspecified R53.1 Weakness

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Legend for Symbols

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Code first venous embolism and thrombosis complicating: abortion, ectopic or molar pregnancy (OØØ-OØ7, OØ8.7) pregnancy, childbirth and the puerperium (O22.-, O87.-) ­

n Use additional code to identify resistance to antimicrobial drugs (Z16.-)

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Use additional code (B95-B97), to identify infectious agent

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­Use an external cause code following the code for the musculoskeletal condition, if applicable, to identify the cause of the musculoskeletal condition

v

Use additional code to identify:

major osseous defect, if applicable (M89.7-)

personal history of (healed) osteoporosis fracture, if applicable (Z87.31Ø)

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Code first human immunodeficiency virus [HIV] disease complicating pregnancy, childbirth and the puerperium, if applicable (O98.7-)

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Code first obesity complicating pregnancy, childbirth and the puerperium, if applicable (O99.21-) Use additional code to identify body mass index (BMI), if known (Z68.-)

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Use additional code for advserse effect, if applicable, to identify drug (T36-T5Ø with fifth or sixth character 5) Ω Use additional code to identify any applicable history of disease code (Z86-Z87)

p Use additional code to identify abnormal findings § Use additional code:

for screening for human papillomavirus, if applicable (Z11.51) for screening vaginal pap smear, if applicable (Z12.72) to identify acquired absence of uterus, if applicable (Z9Ø.71-)

¥ Use additional code for recurrent pregnancy loss, if applicable (N96, O26.2-)

ù Use additional code to identify any family history of malignant neoplasm (Z8Ø.-)

l

Use additional code to identify:

exposure to environmental tobacco smoke (Z77.22) history of tobacco use (Z87.891)

occupational exposure to environmental tobacco smoke (Z57.31) tobacco dependence (F17.-)

tobacco use (Z72.Ø)

ø Code first, if applicable, any causal condition, such as:

enlarged prostate (N4Ø.1)

t

Code also, if applicable, viral hepatitis (acute) (chronic) (B15-B19)

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Code first human immunodeficiency virus [HIV] disease complicating pregnancy, childbirth and the puerperium, if applicable (O98.7-)

Use additional code(s) to identify all manifestations of HIV infection q Code also any follow-up examination (ZØ8-ZØ9)

À Code also any therapeutic drug level monitoring (Z51.81)

±

Code first associated neoplasm

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Use additional code to identify any insulin use (Z79.4)

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Use additional code from category Z3A, Weeks of gestation, to identify the specific week of the pregnancy √ Use additional code to identify any retained foreign body, if applicable (Z18.-)

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Code also any associated maternal condition

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Code first poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4 or 6) Use additional code for adverse effect, if applicable, to identify drug (T36-T5Ø with fifth or sixth character 5)

Genetic ICD-10-CM Client Aid - Addendum

Diagnosis

Code

Diagnosis (sign or symptom)–Supervision of other normal pregnancy

Z34.91 Encounter for supervision of normal pregnancy, unspecified, first trimester Z34.92 Encounter for supervision of normal pregnancy, unspecified, second trimester Z34.93 Encounter for supervision of normal pregnancy, unspecified, third trimester Z34.9Ø Encounter for supervision of normal pregnancy, unspecified, unspecified trimester Z34.81 Encounter for supervision of other normal pregnancy, first trimester

Z34.82 Encounter for supervision of other normal pregnancy, second trimester Z34.83 Encounter for supervision of other normal pregnancy, third trimester Z34.8Ø Encounter for supervision of other normal pregnancy, unspecified trimester

Diagnosis

Code

Diagnosis (sign or symptom)–Supervision of other high-risk pregnancy

OØ9.7Ø Supervision of high-risk pregnancy due to social problems, unspecified trimester OØ9.71 Supervision of high-risk pregnancy due to social problems, first trimester OØ9.72 Supervision of high-risk pregnancy due to social problems, second trimester OØ9.73 Supervision of high-risk pregnancy due to social problems, third trimester OØ9.891 Supervision of other high-risk pregnancies, first trimester

OØ9.892 Supervision of other high-risk pregnancies, second trimester OØ9.893 Supervision of other high-risk pregnancies, third trimester OØ9.899 Supervision of other high-risk pregnancies, unspecified trimester

Diagnosis

Code

Diagnosis (sign or symptom)–Other abnormal findings in blood chemistry

R79.9 Abnormal finding of blood chemistry, unspecified

R78.71 Abnormal lead level in blood R79.Ø Abnormal level of blood mineral

R78.79 Finding of abnormal level of heavy metals in blood

R78.89 Finding of other specified substances, not normally found in blood

E79.Ø Hyperuricemia without signs of inflammatory arthritis and tophaceous disease R79.89 Other specified abnormal findings of blood chemistry

Diagnosis

Code

Diagnosis (sign or symptom)–Other known or suspected fetal abnormality, not elswhere classified, affecting

management of mother, antepartum condition or complication

O35.8XXØ Maternal care for other (suspected) fetal abnormality and damage, not applicable or unspecified

O35.8XX1 Maternal care for other (suspected) fetal abnormality and damage, fetus 1 O35.8XX2 Maternal care for other (suspected) fetal abnormality and damage, fetus 2 O35.8XX3 Maternal care for other (suspected) fetal abnormality and damage, fetus 3 O35.8XX4 Maternal care for other (suspected) fetal abnormality and damage, fetus 4 O35.8XX5 Maternal care for other (suspected) fetal abnormality and damage, fetus 5 O35.8XX9 Maternal care for other (suspected) fetal abnormality and damage, other fetus

Diagnosis

Code

Diagnosis (sign or symptom)–Unspecified hepatitis

K75.3 Granulomatous hepatitis, not elsewhere classified K75.9 Inflammatory liver disease, unspecified

K75.81 Nonalcoholic steatohepatitis (NASH) K75.2 Nonspecific reactive hepatitis

K75.89 Other specified inflammatory liver diseases K76.4 Peliosis hepatis

K71.2 Toxic liver disease with acute hepatitis K71.Ø Toxic liver disease with cholestasis

K71.51 Toxic liver disease with chronic active hepatitis with ascites

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K71.5Ø Toxic liver disease with chronic active hepatitis without ascites K71.4 Toxic liver disease with chronic lobular hepatitis

K71.3 Toxic liver disease with chronic persistent hepatitis K71.7 Toxic liver disease with fibrosis and cirrhosis of liver K71.11 Toxic liver disease with hepatic necrosis, with coma K71.1Ø Toxic liver disease with hepatic necrosis, without coma K71.6 Toxic liver disease with hepatitis, not elsewhere classified K71.8 Toxic liver disease with other disorders of liver

K71.9 Toxic liver disease, unspecified

Diagnosis

Code

Diagnosis (sign or symptom)–Tobacco use disorder

F17.221 Nicotine dependence, chewing tobacco, in remission F17.22Ø Nicotine dependence, chewing tobacco, uncomplicated F17.211 Nicotine dependence, cigarettes, in remission

F17.21Ø Nicotine dependence, cigarettes, uncomplicated

F17.291 Nicotine dependence, other tobacco product, in remission F17.29Ø Nicotine dependence, other tobacco product, uncomplicated F17.2Ø1 Nicotine dependence, unspecified, in remission

F17.2ØØ Nicotine dependence, unspecified, uncomplicated

Diagnosis

Code

Diagnosis (sign or symptom)–Chromosomal abnormality in fetus, affecting management of mother, antepartum

O35.1XXØ Maternal care for (suspected) chromosomal abnormality in fetus, not applicable or unspecified

O35.1XX1 Maternal care for (suspected) chromosomal abnormality in fetus, fetus 1 O35.1XX2 Maternal care for (suspected) chromosomal abnormality in fetus, fetus 2 O35.1XX3 Maternal care for (suspected) chromosomal abnormality in fetus, fetus 3 O35.1XX4 Maternal care for (suspected) chromosomal abnormality in fetus, fetus 4 O35.1XX5 Maternal care for (suspected) chromosomal abnormality in fetus, fetus 5 O35.1XX9 Maternal care for (suspected) chromosomal abnormality in fetus, other fetus

Diagnosis

Code

Diagnosis (sign or symptom)–Other malignant lymphomas, unspecified site, extranodal and solid organ sites

C82.5Ø Diffuse follicle center lymphoma, unspecified site

C82.59 Diffuse follicle center lymphoma, extranodal and solid organ sites C84.9Ø Mature T/NK-cell lymphomas, unspecified, unspecified site

C84.99 Mature T/NK-cell lymphomas, unspecified, extranodal and solid organ sites C84.AØ Cutaneous T-cell lymphoma, unspecified, unspecified site

C84.A9 Cutaneous T-cell lymphoma, unspecified, extranodal and solid organ sites C84.ZØ Other mature T/NK-cell lymphomas, unspecified site

C84.Z9 Other mature T/NK-cell lymphomas, extranodal and solid organ sites C85.1Ø Unspecified B-cell lymphoma, unspecified site

C85.19 Unspecified B-cell lymphoma, extranodal and solid organ sites C85.2Ø Mediastinal (thymic) large B-cell lymphoma, unspecified site

C85.29 Mediastinal (thymic) large B-cell lymphoma, extranodal and solid organ sites C85.8Ø Other specified types of non-Hodgkin lymphoma, unspecified site

C85.89 Other specified types of non-Hodgkin lymphoma, extranodal and solid organ sites C85.9Ø Non-Hodgkin lymphoma, unspecified, unspecified site

C85.99 Non-Hodgkin lymphoma, unspecified, extranodal and solid organ sites C86.4 Blastic NK-cell lymphoma

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