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Multiplex Suspension Array

Bio-Plex Manager

Software

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Bio-Rad continues to innovate where it matters most.

With Bio-Plex Manager 5.0 software, we offer valuable new

features that extend the power and analysis capabilities of

the Bio-Plex

®

suspension array system. Bio-Plex Manager 5.0 software builds

on the robust, standard-setting, and user-friendly performance you’ve come

to expect from Bio-Rad, the leader in multiplex analysis.

Extract Knowledge Faster

View multiple analytes in one table, or use new charting features that display your data in a variety of ways. And now you can easily share your data by simply exporting your data and charts into reports and presentations.

Make Decisions With More Confidence

Rely on powerful and descriptive statistics using new statistical analysis tools. Internal and external controls allow you to normalize data between different plates, different experiments, or different samples.

Be More Productive

Run assays unattended on your Bio-Plex system, with programmable wash, prep, and shutdown steps.

With more researchers using Bio-Plex Manager software to answer complex biological questions, you can be confident that you’ll receive exceptional support and access to an evergrowing body of research knowledge.

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The mark of superior instrument control software is that it quickly becomes invisible to the user. Bio-Plex Manager software is designed with this philosophy in mind.

The software functions are designed around the way you work and guide you step-by-step through the process.

With Bio-Plex Manager software, you can easily select analytes, enter values for standard curves, or format your samples. Quick-click icons for each step are always in view, and can be selected in any order from any window. Once saved, your protocols can be used again with new sets of samples.

Bio-Plex Manager software has a proven track record and is supported by Bio-Rad’s expert field service and technical support teams.

Quick guide to contextual features and icons, available from any screen.

Evolved Ease of Use

Add analytes to existing preconfigured panels, create custom panels of your own, or automatically import panels into the assay list

Calculate percent change in qualitative assays for grouped samples (same color) vs. a designated reference (solid color)

Automatically calculate mean, percent coefficient of variation (%CV), standard deviation, and standard error for replicate samples

Easily enter standard values with automatic dilution calculator

Enter standard curve values and fit curves to individual analytes or across all analytes in one simple step

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Bio-Plex Manager software delivers powerful productivity tools, increasing your capacity to get more done in less time.

n Set up and automatically run unattended

— allows you to program pre- and post-run maintenance and system shutdown operations

n Automatically add new panels to

available panel list by opening the protocol files of a new assay

Bio-Plex Reservoir

Present data in a variety of chart formats

Present data by gene or by sample

Enhanced Productivity

Bio-Plex Manager software allows easy viewing of results and effective processing of information from your data. It has unique table and chart features that shorten the path from raw data to valuable knowledge.

n View and compare data between

samples and across multiple analytes using new easy-to-read table formats

n Chart and share your results with new

bar chart options, and export your charts into other applications

Effective Data Visualization

Choose sequential data view for each analyte or full table view for all analytes

Add or delete panels to available panels list Easily program maintenance functions

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Effective data analysis dramatically increases your capacity to make the right decisions. Your level of confidence in your results has a direct impact on the direction of your research effort. Bio-Plex Manager software has the most robust data analysis tools in the industry.

n Apply StatLIA 4- and 5-parameter

logistic weighing algorithms to data

n Set outliers in standard curve view n Normalize your results using internal

controls; compare data between plates, experiments, and samples

Percent of recovery shown as selected data label Buttons for easy access to results and protocols

Easy sharing of results Flexible report table options

Advanced Data Analysis

Bio-Plex Manager software offers an expanding set of tools to support specific areas of research, such as gene expression. Tools include internal control capabilities (housekeeping genes) as well as an external control option, allowing you to distinguish between “real” and “observed” differences in your results, whether you are comparing data between samples or across experiments.

Normalization options allow you to correct for sample-loading variability

Selection of three common housekeeping genes used to normalize data across samples in entire data set

Normalization Tools for Gene Expression and Other Applications

External standard curve (may be imported from another assay)

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Multiplex Suspension Array

Bio-Plex Manager

Software

Bio-Plex Manager Software Versions

Bio-Plex Manager 5.0 software, Security Edition, with 21 CFR Part 11 compliance tools, is also available. Both standard and Security Edition versions are available in single-, five-, and ten-user packages.

n Bio-Plex Manager workstation version —

full system control and data analysis

n Bio-Plex Manager desktop version — single-user

version performs protocols, data analysis, and data storage on PCs not linked to the Bio-Plex array reader; does not control the array reader

n Bio-Plex Manager network desktop version —

networks multi-user versions for 1-, 5-, or 10-user access from a central server; performs protocols, data analysis, and data storage; does not control the array reader

Open Platform

Bio-Plex Manager software can be used with any xMAP technology assay from Bio-Rad or any other provider. Bio-Plex Manager software supports Luminex 100 and 200 series instruments and all xMAP technology bead types, including magnetic beads.

Upgrade Kits

Several upgrade kits are available to users of previous versions of Bio-Plex Manager software (3.0, 4.0, and 4.1) and to users of software from other vendors.

Ordering Information Catalog # Description Software

171-STND01 Bio-Plex Manager 5.0 Software, includes 1-user desktop license

171-STND05 Bio-Plex Manager 5.0 Software, includes 5-user network license

171-STND10 Bio-Plex Manager 5.0 Software, includes 10-user network license

171-SCRT00 Bio-Plex Manager 5.0 Workstation License,

Security Edition, upgrades workstation with

Bio-Plex Manager 5.0 software, allows compliance with U.S. FDA 21 CFR Part 11 regulations 171-SCRT01 Bio-Plex Manager 5.0 Software, Security Edition,

includes 1-user desktop license, allows compliance with U.S. FDA 21 CFR Part 11 regulations 171-SCRT05 Bio-Plex Manager 5.0 Software, Security Edition,

includes 5-user network license, allows compliance with U.S. FDA 21 CFR Part 11 regulations 171-SCRT10 Bio-Plex Manager 5.0 Software, Security Edition,

includes 10-user network license, allows compliance with U.S. FDA 21 CFR Part 11 regulations

Upgrade Kits

171-STND23 Bio-Plex Manager 5.0 Software for IS 2.3 System, includes workstation license, validation kit 4.0, MCV plate IV, Bio-Plex reservoir, calibration kit, communication cables for systems with IS 2.3 software 171-SUPG30 Bio-Plex Manager 5.0 Software for 3.0 Workstation,

includes workstation license, validation kit 4.0, MCV plate IV, Bio-Plex reservoir, communication cables to upgrade Bio-Plex Manager 3.0 workstation

171-SUPG40 Bio-Plex Manager 5.0 Software for 4.0 Workstation, includes communication cables to upgrade Bio-Plex Manager 4.0 workstation (standard or Security Edition) 171-SUPG41 Bio-Plex Manager 5.0 Software for 4.1 Workstation,

includes MCV plate IV, Bio-Plex reservoir xMAP and Luminex are trademarks of Luminex Corporation.

Life Science Group

07-0563 1107 Sig 1106 Bulletin 5613 US/EG Rev A

Bio-Rad

Laboratories, Inc.

Web site www.bio-rad.comUSA800 4BIORADAustralia 61 02 9914 2800 Austria 01 877 89 01 Belgium 09 385 55 11Brazil 55 21 3237 9400

Canada 905 712 2771 China 86 21 6426 0808Czech Republic 420 241 430 532 Denmark 44 52 10 00Finland 09 804 22 00 France 01 47 95 69 65

Germany 089 318 84 0 Greece 30 210 777 4396 Hong Kong 852 2789 3300Hungary 36 1 455 8800 India 91 124 4029300 Israel 03 963 6050

Italy 39 02 216091Japan 03 5811 6270 Korea 82 2 3473 4460Mexico 52 555 488 7670 The Netherlands 0318 540666 New Zealand 0508 805 500

Norway 23 38 41 30 Poland 48 22 331 99 99Portugal 351 21 472 7700 Russia 7 495 721 14 04Singapore 65 6415 3188 South Africa 27 861 246 723 Spain34 91 590 5200Sweden08 555 12700Switzerland061 717 95 55Taiwan886 2 2578 7189 United Kingdom020 8328 2000

2001 2007

Now in its fifth generation, Bio-Plex Manager software continues to provide an ever-expanding set of powerful features to the global research community and, with over 2,000 installations, continues to be the most widely used software for xMAP analysis. R el at iv e n um b er o f s of tw ar e u se rs

Bio-Plex Manager software versions

1.0 2.0 3.0 4.0 5.0 4.1

References

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