How To Learn More About The Science Of Addiction

UNITED

Scientifi c

Group

RDS-1

November 16-18, 2015

San Francisco, USA

Inaugural

Reward Deficiency

Syndrome Summit

Reward Deficiency Syndrome (RDS) in the 21

_{Century: Epigenetics,}

Neurogenetic, Neuroimaging Tools for Therapy and Recovery

Kenneth Blum

University of Florida, USA

Presentation on: “Dopamine Resistance” in Brain Reward Circuitry as a Function of Genetic Addiction Risk Score (Garspdx) Polymorphisms in RDS: Synaptamine Complex Variant (Kb220z) Induced “Dopamine Sensitivity” as a Pro-recovery Agent

Kenneth Blum is widely designated as Father of Psychiatric Genetics because of the DRD2 gene and its correlation with various psychiatric disorders including the “Reward Deficiency Syndrome (RDS)” which term he has coined. He is also known as the “Father of Neuro-Nutrient Therapy” for his discovery of successful nutrient therapy for RDS. He holds numerous domestic and foreign patents and is co-founder and Chairman & Chief Scientific Officer (CSO) of LifeGen Inc. He is a former Full Professor in the Department of Pharmacology, University of Texas Health Science Center, San Antonio, Texas; Volunteer Professor in the Department of Psychiatry & McKnight Brain Institute, University of Florida College of Medicine, Gainesville, Florida and Adjunct Full Professor of Psychiatry at the University of Vermont College of Medicine, Burlington, Vermont. He currently serves as Neuroscience advisor for Dominion Diagnostics LLC, North Kingstown, Rhode Island, Malibu Beach Recovery Center, Malibu Beach California, and is the Scientific Director of PATH Foundation, New York. He is an honorary Faculty of IIOAB, India. He has been recently appointed CSO of G&G Holistic Addiction Treatment Centers in North Miami Beach Florida. To his credit he has over 400 publications in peer reviewed journals, 14 books and has received many awards including a Lifetime Achievement Award from the National Institute of Holistic Addiction Studies.

KEYNOTE SPEAKERS

Monday, November 16, 2015

DAY 1

David E. Smith is recognized as a national leader in the treatment of addictive disease, the psychopharmacology of drugs, new research strategies in the management of drug abuse problems, and appropriate prescribing practices for physicians. He teaches that addiction is a primary medical illness which is best treated in a multidisciplinary fashion, utilizing the group process and the 12-Step programs of Alcoholics Anonymous, Narcotics Anonymous and Cocaine Anonymous. He lectures on the management of psychoactive drug dependence, including cocaine, alcohol and prescription drugs. He also speaks on the subjects of impaired and recovering clinicians, substance abuse in the workplace, dual diagnosis disorders, and substance abuse and the criminal justice system, among many other topics. He provides medical review of DOT and private industry drug testing and prescription drug plans, and legal consultation. Dr. Smith founded the Haight Ashbury Free Clinics in 1967, inaugurating the principle of “Health Care is a Right, not a Privilege”. He has served on federal, state and local bodies addressing substance use, abuse and treatment, and has received numerous awards, including the 2013 Peter E. Haas Award from the University of California Berkeley. He lectures extensively and is the author/co-author of over 360 professional articles and books, including Unchain Your Brain: 10 Steps to Breaking the Addictions that Steal Your Life, with Dr. Daniel Amen.

David E. Smith

University of California, USA

Presentation on:Process Addictions and Addiction Transfer

Registrations: 08:30-09:00

Keynote session: 09:30-12:20

Introduction: 09:00-09:30

KEYNOTE SPEAKERS

Monday, November 16, 2015

DAY 1

David Baron

USC University, USA

Presentation on: Reward Deficiency Syndrome in Sports Psychiatry

David Baron is currently Professor and Vice Chair, and Chief of Psychiatry at University Hospital at the Keck School of Medicine, University of Southern California. Dr. Baron is also the Director of the Global Center for Exercise, Psychiatry and Sport at USC and Chairman of the Section on Exercise, Psychiatry and Sport for the World Psychiatric Association/World Health Organization. He is also a current member of the Executive Board of Directors for the International Society of Sports Psychiatrists and the 2010 Consumer Council of America “Top Doc” for Sport Psychiatry. Dr. Baron is the former Deputy Clinical Director of the National Institute of Mental Health and Chair of the Department Psychiatry at the NIH graduate school 1989-1997 and Temple University (1998-2010). He developed, and holds the copyright on the only validated depression screener specifical for athletes (BDSA), which is currently in use in over 7 countries. He has over 30 years of clinical experience in sports medicine and sports psychiatry and has worked with athletes of all ages and levels of competition including NCAA, Olympic, and professional. He has published over 130 peer reviewed publications and presented over 300 scientific presentations in the US and over 30 invited international talks, many in the area of Doping in Sports and Depression, Drug Use and Concussion in athletes. His current clinical and research interests are in the neuropsychiatric sequel of recurrent sub-clinical concussion and TBI in athletes, specifically focused on developing more sensitive, user-friendly screening instruments and methods, and increasing public awareness of this growing problem.

Panayotis K. Thanos

University of Buffalo, USA

Presentation on: Dopamine D2, Obesity and Reward Deficiency Syndrome

Panayotis K. Thanos is interested in translational research utilizing various rodent models of psychopathology to better understand the mechanisms involved in substance use disorders (SUD) and addiction including the role of dopamine signaling, genes, environment, as well brain circuit mapping and connectivity changes in food, drug and alcohol abuse. Dr. Thanos is the Director of the Behavioral Neuropharmacology and Neuroimaging Lab and has authored more than 85 peer reviewed articles on reward and addiction.

10:20-10:45 11:05-11:30

KEYNOTE SPEAKERS

Monday, November 16, 2015

DAY 1

In his 35-year career at VA/UCSF, Dr. Banys has developed two addiction fellowships, has engaged in direct clinical care, research, and teaching of UCSF psychiatry residents and substance abuse physician fellows. Most recently he spent 2½ years living and working in Hanoi to assist in scaling up methadone programs and to develop community screenings for depression. He is a section co-editor (Special Problems) for the 2014 edition of the ASAM Textbook of Addiction Medicine. He is a member of Lt. Governor Gavin Newsom’s Blue Ribbon Commission (BRC) on marijuana law reform, and has written a series of marijuana reform-related briefings available on the BRC and CSAM websites.

John J. Giordano is the former president and founder of the prestigious G & G Holistic Addiction Treatment Center, a 62 bed in-patient/out-patient JACHO accredited addiction treatment facility. He is a therapist, a Certified Addiction Professional (CAP), a Master Addictions Counselor (MAC), and a Certified Criminal Justice Specialist (CCJS). He also earned a Masters Certification in Neuro linguistics Programming (NLP), and is a Certified Eye Movement Desensitization and Reprocessing (EMDR) Specialist and a professional expert witness for the state and federal government. He is also a Karate Grand Master 10th degree black belt. He is also certified in Traditional Indian Medicine as well as Mindfulness and Powerful Mind-Body Awareness Therapy Skills. Most recently, he was awarded an Honorary Doctorate of Humane Letters from Mount Sinai University. His Influential book, Proven Holistic Treatment for Addiction & Chronic Relapse, is being utilized by several state hospitals and numerous treatment centers across the country.

Peter Banys

The University of California, USA

National Institute For Holistic

John J Giordano

Addiction Studies, USA

International Drug Policy Reforms and Cannabis Legalization in California

Presentation on:Comprehensive Holistic Approaches in Addiction Medicine

SUBSTANCE ABUSE

Session Chair: TBD

SPEAKERS:

12:20-16:20

Monday, November 16, 2015

DAY 1

Presentation on: Polysubstance Use and Brain Function. Why Bother? Dieter J. Meyerhoff, University of California San Francisco, USA

Presentation on: Interactions Between Methamphetamine and Stress: A Dangerous Combination

Bryan Yamamoto, Indiana University School of Medicine, USA

Presentation on:Mental Health and Substance Use Correlates in a Population Sample of Canadian Adults with and Without a History of Traumatic Brain Injuries

Gabriela Ilie, St. Michael’s Hospital, Canada

Presentation on: Role of A5 Subunit Containing Nicotinic Receptors in Key Circuits Involved In Nicotinic Addiction and Beyond

Rouba Kozak, Pfizer Inc., USA

Presentation on: ADAR2-Dependent GluA2 Editing Regulates Cocaine Seeking Ghazaleh Sadri Vakili, Mass General Institute for Neurodegenerative Disease, USA

Presentation on: The Concerning State of Opioid Addiction Trials and Guidelines: To Whom Does this Evidence Apply

Zainab Samaan, McMaster University, Canada

Presentation on: Medication Abuse in Europe: Which Pharmacoepidemiological Ressources?

Maryse Lapeyre Mestre, University of Toulouse, France

Michael R. DeLeon, Steered Straight, Inc., USA

An American Epidemic

Presentation on: “This is your brain on drugs”: Adolescent substance use prevention through neuroscience education

Sion K Harris, Boston Children’s Hospital, USA

Lunch Break: 13:20-14:20

Presentation on: Family Members Affected by a Relative’s Substance Misuse Looking for Social Support: Who Are They?

Maria de Fatima Padin, Federal University of Sao Paul, Brazil

16:00-16:20

Coffee Break: 16:20-16:40

Special Evening Movie

KEYNOTE SPEAKERS

Tuesday, November 17, 2015

DAY 2

Rajendra Badgaiyan

University of Minnesota, USA

Presentation on: Dopamine Neurotransmission In Reward Deficiency Syndrome

Rajendra Badgaiyan is the Director and Principal Investigator of Molecular and Functional Brain Imaging Laboratory and Director of the University Laboratory for Advanced Radiochemistry. He graduated from Gandhi Medical College, Bhopal in India and completed his psychiatry residency training at Harvard Medical School. He had postdoctoral training in cognitive neuroscience at University of Oregon, University of Pittsburgh and Harvard University. He also had training in molecular imaging at Massachusetts General Hospital, Boston, and clinical research training at MIT. He is board certified in General Psychiatry and in Addiction Medicine. He is a member of a numerous National and International Scientific Societies. He is the Editor-in-Chief of 7 international scientific journals and a member of the editorial board of over 40 other scientific publications. He has organized a number of International conferences and symposia.

Timothy D. Brewerton, MD, DFAPA, FAED, DFAACAP is Clinical Professor of Psychiatry & Behavioral Sciences at the MUSC (Charleston), and Executive Medical Director of the Hearth Center for Eating Disorders (Columbia, SC). He is triple board certified in general, child/adolescent and forensic psychiatry; Distinguished Fellow of the APA and the AACAP; Founding Fellow of the Academy of Eating Disorders; former president of the Eating Disorders Research Society; author of over 140 articles/book chapters; Editor of the Clinical Handbook of Eating Disorders: An Integrated Approach (2004), Co-editor of Eating Disorders, Addictions, and Substance Use Disorders: Research, Clinical and Treatment Perspectives (2014).

Timothy D. Brewerton

The Hearth Center for Eating Disorders, USA

09:00-09:25 09:25-09:50

Registrations: 09:00-09:30

KEYNOTE SPEAKERS

Tuesday, November 17, 2015

DAY 2

Marcelo Febo

University of Florida, USA

Presentation on: Resting State Functional Connectivity in Rat Brain During Extended Daily Access to Cocaine and Abstinence

Marcelo Febo completed his PhD at the University of Puerto Rico Medical School and postdoctoral studies at the University of Massachusetts Medical Center. His work focuses on measuring

in vivo functional and structural changes in the rat

brain following chronic drug exposure. Over the past decade he has pursued this goal through the use of high field functional magnetic resonance imaging in awake rats and mice. He has been funded early in his career by the National Institute on Drug Abuse to examine the relationship between cocaine sensitization and alterations in maternal brain activity. He is presently Program Director of Translational Research Imaging at the University of Florida Brain Institute and is also a faculty member of the Department of Psychiatry.

Giulio Maria Pasinetti

Mount Sinai School of Medicine, USA

Giulio Maria Pasinetti is a Professor of Psychiatry, Professor of Neuroscience and Professor of Geriatrics and Adult Development, in the Department of Psychiatry at Mount Sinai School of Medicine, New York. He graduated from Milan University School of Medicine in 1982, and he received his Ph.D. from the University of Milan in 1988. He joined the Mount Sinai School of Medicine’s faculty in 1996 and has consistently maintained an outstanding record of excellence and exceptional productivity.

He was also recently awarded with an NIH funded research grant supporting a ‘’Center of Excellence for Research in Complementary and Alternative Medicine in Alzheimer’s disease,’’ of which he is the Principal Investigator and Director. The NIH funded Center is the first in the country exploring the potential beneficial role of natural grape -derived polyphenolic compounds implicated in mechanisms associated with the prevention of Alzheimer’s disease (AD) neuropathology. He also serves as the Director of the Basic and Biomedical Research and Training Program, GRECC James J. Peters Veterans Affairs Medical Center at the Bronx VA.

09:50-10:15 10:35-11:00

Tuesday, November 17, 2015

DAY 2

SPEAKERS: 11:00-16:00

ADDICTION TREATMENT

ALCOHOLISM

Presentation on: Promoting Epigenetic Networks using Biopsycho-Spiritual Approaches for Treating Prescription Opioid Addiction

Deborah Matteliano, State University of New York, USA

11:20-11:40

Presentation on:An Assessment of Outcomes Measure Implementation in the Addiction Treatment Space

Alexander Moler, Alexander Carlin, The Coalition Against Drug Abuse, USA

Presentation on: Modeling Recovery

Brett C. Ginsburg, The University of Texas Health Science Center at San Antonio, USA

11:40-12:00

Presentation on: Getting in and Out Whole: Connecting with Patients Emotional Pain in the Psychiatric Setting

Judith Van Sant, Our Lady of Lourdes School of Nursing, USA

12:00-12:20

12:20-12:40

Presentation on: Motivational Interviewing - Patient - Centered Communication in Brief Health Care Encounters

Tatjana Petrova, Chicago State University, USA

14:00-14:20

Presentation on: Greater Mesolimbic Loss-Sensitivity in Young Adult Social Drinkers at Risk for Alcohol Dependence

Jane E Joseph, Medical University of South Carolina, USA

15:00-15:20

Presentation on: Dopaminergic Pathways in Alcohol Dependence: First Data on Indian Population

Meera Vaswani, All India Institute of Medical Sciences, India

15:20-15:40

Presentation on: Integrating Substance Use and Eating Disorder Treatment: Adapting Evidence Based Treatments

Therese K. Killeen, University of South Carolina, USA

12:40-13:00

Lunch Break: 13:00-14:00

Presentation on: Similarities and Differences in Neurocognitive and Neuroimaging Findings among Internet Gaming Disorder and Alcohol Use Disorder

Jung Seok Choi, Seoul National University College of Medicine, South Korea

14:40-15:00

Presentation on: Opioid Medications: Efficacy and Risks Norman S. Miller, Bear River Health at Walloon Lake, USA

11:00-11:20

Presentation on: Mechanisms of Pain and Opioid Pharmacology Thersilla Oberbarnscheidt, Central Michigan University, USA

14:20-14:40

DAY 3

Wednesday November 18, 2015

Presentation on: Quality of Life of Users of Psychoactive Substances, Relatives and Non-Users

Tais de Campos Moreira, Federal University of Health Sciences of Porto Alegre /UFCSPA, Brazil

SPEAKERS: 09:30-12:10

Session Chair: TBD

Presentation on: Expression of Reward Reficiency Syndrome Depends on More than Dopamine

David Nussbaum, University of Toronto, Canada

09:30-09:50

Presentation on: Fetal Alcohol Spectrum Disorder-Can Prenatal Nutrition Strategy Make a Difference for Brain Development?

Miyoung Suh, University of Manitoba, Canada

09:50-10:10

Presentation on: Reward Deficiency Syndrome: Attentional/Arousal Subtypes, Limitations of Current Diagnostic Nosology, and Future Research

Edward Justin Modestino, Boston University School of Medicine, USA

10:10-10:30

Presentation on:The Oxidative Stress Induced Nitric Oxide Dependent

Mitochondrial DNA Overproliferation and Deletion in the Context of the Cancer and Neurodegeneration: Recent Challenge

Gjumrakch Aliev, GALLY International Biomedical Research Consulting LLC, USA

10:30-10:50

11:10-11:30

Coffee Break: 16:00-16:20

Gregory A. Smith,MD, Pain MD Productions, USA http://drgregorysmith.com/

American Addict 2

Special Evening Movie

16:20-17:20

Coffee Break: 10:50-11:10

Presentation on: Role of Mesolimbic Dopamine in Food and Drug Reward Valentina Bassareo, University of Cagliari, Italy

11:30-11:50

Presentation on: Interactor Toy Robot Encourages Verbal and Emotional Expressions in Autism

Irini Giannopulu, IHU-A-ICM Prisme Virtual Reality, Paris

12:10-12:30

Presentation on: A Glutamatergic Reward Input from the Dorsal Raphe to the Ventral Tegmental Dopamine Neurons

Marisela Morales, National Institute on Drug Abuse, USA

11:50-12:10