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Billing Information

University of Hong Kong Li Ka Shing Faculty 10A Sassoon Road Pokfulam, HK 0 Hong Kong

Payment Method PO#: 623032 Purchase Order

Details

NULL Sample(s) from: 30-Aug-2019 Collection Date 06-Sep-2019

Arrival Date Approval Date

10-Sep-2019

Notes

Lab. No. 1909M201-1909M208, Location: Conventional Experimental Holding Area – Laboratory Block, Li Ka Shing Faculty of Medicine (CA-FMB)

Diagnostic Summary

PDG ? +/-+ Tested Test Colony 8 8 0 0 0 n/d MFIA MHV

UHK MFIA Mouse Full Profile

8 8 0 0 0

n/d MFIA MNV

UHK MFIA Mouse Full Profile

+ = Positive, +/- = Equivocal, ? = Indeterminate, PDG = Pending

To assure the health status of your research animal colonies, it is essential that you understand the sources, pathobiology, diagnosis and control of pathogens and other adventitious infectious agents that may cause research interference. We have summarized this important information in infectious agent Technical Sheets, which you can view by visiting

http://www.criver.com/info/disease_sheets.

Printed on 10-Sep-2019 at 19:45 GMT

(2)

Notes

Lab. No. 1909M201-1909M208, Location: Conventional Experimental Holding Area – Laboratory Block, Li Ka Shing Faculty of Medicine (CA-FMB)

Serology

Results approved by Castillo, Luz on 10 Sep 2019

1 2 3 4 5 6 7 8

1909M201, 1909M202, 1909M203, 1909M204, 1909M205, 1909M206, 1909M207, 1909M208, Rm.AR6 Rm.AR6 Rm.AR7 Rm.AR7 Rm.AR8 Rm.AR8 Rm.AR9 Rm.AR9

MFIA SEND - - - - - - - -MFIA PVM - - - - - - - -MFIA MHV + + + + + + + + MFIA MVM - - - - - - - -MFIA MPV-1 - - - - - - - -MFIA MPV-2 - - - - - - - -MFIA MPV-5 - - - - - - - -MFIA NS-1 - - - - - - - -MFIA MNV + + + + + + + + MFIA GDVII - - - - - - - -MFIA REO - - - - - - -

-MFIA EDIM (ROTA-A) - - - - - - -

-MFIA LCMV - - - - - - -

-MFIA ECTRO - - - - - - -

-MFIA MAV 1 & 2 - - - - - - -

-MFIA MCMV - - - - - - - -MFIA K - - - - - - - -MFIA MTLV - - - - - - - -MFIA POLY - - - - - - - -MFIA HTNV (HANT) - - - - - - - -MFIA MPUL - - - - - - - -MFIA CARB - - - - - - - -MFIA LDV - - - - - - - -MFIA CPIL - - - - - - - -MFIA ECUN - - - - - - - -MFIA PHV - - - - - - - -MFIA Anti-Ig P P P P P P P P

Serology Profile: UHK MFIA Mouse Full Profile

Printed on 10-Sep-2019 at 19:45 GMT

(3)

Notes

Lab. No. 1909M201-1909M208, Location: Conventional Experimental Holding Area – Laboratory Block, Li Ka Shing Faculty of Medicine (CA-FMB)

Remarks

MFIA/IFA/ELISA/WIB Results: - = Negative; +/- = Equivocal; + = Moderate to strong positive; TC = Non-specific reaction with tissue control; I = Indeterminate or Inconclusive; IN = result interpreted as non-specific because not confirmed by alternative serologic assay or diagnostic methodology for other serologic assays, PDG = pending, QNS = Quantity not sufficient.The anti-immunoglobulin (Anti-Ig) MFIA verifies that a serum specimen contains a sufficient concentration of immunoglobulin to be suitable for serologic testing. A result of P (for Pass) corresponds to a median fluorescence index (MFI) at or above the Anti-Ig assay cutoff, typically >= 7000. An Anti-Ig assay result of F (for Fail), assigned if the MFI is below the cutoff, might occur because the sample was received too dilute, was collected from an immunocompromised host or was from a species other than the one for which the MFIA is intended. If a sample fails the Anti-Ig MFIA, then negative and borderline results in MFIA for microbial antibodies are considered I (for inconclusive).

Printed on 10-Sep-2019 at 19:45 GMT

(4)

Notes

Lab. No. 1909M201-1909M208, Location: Conventional Experimental Holding Area – Laboratory Block, Li Ka Shing Faculty of Medicine (CA-FMB)

Sample Information

Number Code Species Colony Strain Age Sex

1 Sentinel/ ICR (CD-1) Adult Female 1909M201, Rm.AR6 Mouse n/d 2 Sentinel/ ICR (CD-1) Adult Female 1909M202, Rm.AR6 Mouse n/d 3 Sentinel/ ICR (CD-1) Adult Female 1909M203, Rm.AR7 Mouse n/d 4 Sentinel/ ICR (CD-1) Adult Female 1909M204, Rm.AR7 Mouse n/d 5 Sentinel/ ICR (CD-1) Adult Female 1909M205, Rm.AR8 Mouse n/d 6 Sentinel/ ICR (CD-1) Adult Female 1909M206, Rm.AR8 Mouse n/d 7 Sentinel/ ICR (CD-1) Adult Female 1909M207, Rm.AR9 Mouse n/d 8 Sentinel/ ICR (CD-1) Adult Female 1909M208, Rm.AR9 Mouse n/d Printed on 10-Sep-2019 at 19:45 GMT Page 4 of 4

(5)

Billing Information

University of Hong Kong Li Ka Shing Faculty 10A Sassoon Road Pokfulam, HK 0 Hong Kong

Payment Method PO#: 623032 Purchase Order

Details

NULL Sample(s) from: 30-Aug-2019 Collection Date 06-Sep-2019

Arrival Date Approval Date

09-Sep-2019

Notes

Lab. No. 1909R201-1909R202, Location: Conventional Experimental Holding Area – Laboratory Block, Li Ka Shing Faculty of Medicine (CA-FMB)

Diagnostic Summary

PDG ? +/-+ Tested Test Colony 2 2 0 0 0 n/d MFIA PCAR ("RRV")

UHK MFIA Rat Full Profile

+ = Positive, +/- = Equivocal, ? = Indeterminate, PDG = Pending

To assure the health status of your research animal colonies, it is essential that you understand the sources, pathobiology, diagnosis and control of pathogens and other adventitious infectious agents that may cause research interference. We have summarized this important information in infectious agent Technical Sheets, which you can view by visiting

http://www.criver.com/info/disease_sheets.

Printed on 09-Sep-2019 at 19:30 GMT

(6)

Notes

Lab. No. 1909R201-1909R202, Location: Conventional Experimental Holding Area – Laboratory Block, Li Ka Shing Faculty of Medicine (CA-FMB)

Serology

Results approved by Castillo, Luz on 09 Sep 2019

1 2 1909R201, 1909R202, Rm.AR1 Rm.AR1 MFIA SEND - -MFIA PVM - -MFIA SDAV - -MFIA KRV - -MFIA H-1 - -MFIA RPV - -MFIA RMV - -MFIA NS-1 - -MFIA REO - -MFIA RTV -

-MFIA MAV 1 & 2 -

-MFIA HTNV (HANT) - -MFIA MPUL - -MFIA ECUN - -MFIA CARB - -MFIA PCAR ("RRV") + + MFIA CPIL - -MFIA LCMV -

-MFIA IDIR (ROTA-B) -

-MFIA Anti-Ig P P

Serology Profile: UHK MFIA Rat Full Profile Remarks

MFIA/IFA/ELISA/WIB Results: - = Negative; +/- = Equivocal; + = Moderate to strong positive; TC = Non-specific reaction with tissue control; I = Indeterminate or Inconclusive; IN = result interpreted as non-specific because not confirmed by alternative serologic assay or diagnostic methodology for other serologic assays, PDG = pending, QNS = Quantity not sufficient.The anti-immunoglobulin (Anti-Ig) MFIA verifies that a serum specimen contains a sufficient concentration of immunoglobulin to be suitable for serologic testing. A result of P (for Pass) corresponds to a median fluorescence index (MFI) at or above the Anti-Ig assay cutoff, typically >= 7000. An Anti-Ig assay result of F (for Fail), assigned if the MFI is below the cutoff, might occur because the sample was received too dilute, was collected from an immunocompromised host or was from a species other than the one for which the MFIA is intended. If a sample fails the Anti-Ig MFIA, then negative and borderline results in MFIA for microbial antibodies are considered I (for inconclusive).

Printed on 09-Sep-2019 at 19:30 GMT

(7)

Notes

Lab. No. 1909R201-1909R202, Location: Conventional Experimental Holding Area – Laboratory Block, Li Ka Shing Faculty of Medicine (CA-FMB)

Sample Information

Number Code Species Colony Strain Age Sex

1 Sentinel/ CD(SD)IGS (Sprague Dawley) Adult Female 1909R201, Rm.AR1 Rat n/d 2 Sentinel/ CD(SD)IGS (Sprague Dawley) Adult Female 1909R202, Rm.AR1 Rat n/d Printed on 09-Sep-2019 at 19:30 GMT Page 3 of 3

(8)

Billing Information

University of Hong Kong Li Ka Shing Faculty 10A Sassoon Road Pokfulam, HK 0 Hong Kong

Payment Method PO#: 623032 Purchase Order

Details

NULL Sample(s) from: 29-Aug-2019 Collection Date 06-Sep-2019

Arrival Date Approval Date

10-Sep-2019

Notes

Lab. No. 1909M501-1909M502, Location: Conventional Experimental Holding Area - Kadoorie Biological Sciences Building (CA-KA)

Diagnostic Summary

PDG ? +/-+ Tested Test Colony 2 2 0 0 0 n/d MFIA MHV

UHK MFIA Mouse Full Profile

2 2 0 0 0

n/d MFIA MNV

UHK MFIA Mouse Full Profile

+ = Positive, +/- = Equivocal, ? = Indeterminate, PDG = Pending

To assure the health status of your research animal colonies, it is essential that you understand the sources, pathobiology, diagnosis and control of pathogens and other adventitious infectious agents that may cause research interference. We have summarized this important information in infectious agent Technical Sheets, which you can view by visiting

http://www.criver.com/info/disease_sheets.

Printed on 10-Sep-2019 at 19:45 GMT

(9)

Notes

Lab. No. 1909M501-1909M502, Location: Conventional Experimental Holding Area - Kadoorie Biological Sciences Building (CA-KA)

Serology

Results approved by Castillo, Luz on 10 Sep 2019

1 2 1909M501, 1909M502, Rm.8S22 Rm.8S22 MFIA SEND - -MFIA PVM - -MFIA MHV + + MFIA MVM - -MFIA MPV-1 - -MFIA MPV-2 - -MFIA MPV-5 - -MFIA NS-1 - -MFIA MNV + + MFIA GDVII - -MFIA REO -

-MFIA EDIM (ROTA-A) -

-MFIA LCMV -

-MFIA ECTRO -

-MFIA MAV 1 & 2 -

-MFIA MCMV - -MFIA K - -MFIA MTLV - -MFIA POLY - -MFIA HTNV (HANT) - -MFIA MPUL - -MFIA CARB - -MFIA LDV - -MFIA CPIL - -MFIA ECUN - -MFIA PHV - -MFIA Anti-Ig P P

Serology Profile: UHK MFIA Mouse Full Profile

Printed on 10-Sep-2019 at 19:45 GMT

(10)

Notes

Lab. No. 1909M501-1909M502, Location: Conventional Experimental Holding Area - Kadoorie Biological Sciences Building (CA-KA)

Remarks

MFIA/IFA/ELISA/WIB Results: - = Negative; +/- = Equivocal; + = Moderate to strong positive; TC = Non-specific reaction with tissue control; I = Indeterminate or Inconclusive; IN = result interpreted as non-specific because not confirmed by alternative serologic assay or diagnostic methodology for other serologic assays, PDG = pending, QNS = Quantity not sufficient.The anti-immunoglobulin (Anti-Ig) MFIA verifies that a serum specimen contains a sufficient concentration of immunoglobulin to be suitable for serologic testing. A result of P (for Pass) corresponds to a median fluorescence index (MFI) at or above the Anti-Ig assay cutoff, typically >= 7000. An Anti-Ig assay result of F (for Fail), assigned if the MFI is below the cutoff, might occur because the sample was received too dilute, was collected from an immunocompromised host or was from a species other than the one for which the MFIA is intended. If a sample fails the Anti-Ig MFIA, then negative and borderline results in MFIA for microbial antibodies are considered I (for inconclusive).

Printed on 10-Sep-2019 at 19:45 GMT

(11)

Notes

Lab. No. 1909M501-1909M502, Location: Conventional Experimental Holding Area - Kadoorie Biological Sciences Building (CA-KA)

Sample Information

Number Code Species Colony Strain Age Sex

1 Sentinel/ ICR (CD-1) Adult Female 1909M501, Rm.8S22 Mouse n/d 2 Sentinel/ ICR (CD-1) Adult Female 1909M502, Rm.8S22 Mouse n/d Printed on 10-Sep-2019 at 19:45 GMT Page 4 of 4

(12)

Guinea pig cvtomegalovirus GoCMV Herpesviridae Betaherpesvirus GP

Hantaan HTNV(HAND Bunvaviridae Hantavirus M.R

Infectious pancreatic necrosis virus IPNV Birnaviridae Aouabirnavirus Z Infectous spleen and kidney necrosis virus ISKNV Iridoviridae Megalocvtivirus Z Influenza A virus INFA Orthomvxoviridae Influenzavirus A F

Kilhani rat virus KRV Parvoviridae Parvovirus R

Lactate dehydroqenase-elevatina virus LDV/LDH Arteriviridae Anerivirus M

Liunaan virus LV Picomaviridae Parechovinjs R

Lymphocvtic cfiorlomeninaitis virus LCMV Arenaviridae Arenavirus M, R. GP. H Minute virus of mice MVM Parvoviridae Parvovirus M Mouse cvtomegalovirus MCMV Herpesviridae Betaherpesvirus M Mouse hepatitis virus MHV Coronaviridae Coronavirus M

Mouse pan/ovirus MPV-1/.2/.5 Parvoviridae Parvovirus M

Mouse pneumonitis virus K Polvomaviridae Polvomavlrus M

Mouse thvmic virus MTLV Herpesviridae Unclassified M

Marine norovirus MNV Calidviridae Norovirus M

Marine rotavirus EDIM/ROTA-A Reoviridae Rotavirus M MvcoDlasma arthriUdis MARTH Mvcoolasmataceae Mvcoplasma M.R

MvcoDlasma pulmonis MPUL Mvcoplasmataceae Mvcoplasma M.R

Mvxomatosis virus MYXO Poxviridae Leporipoxirus Rb Parainfluenza virus (tvpe 1) PiV-1 Paramvxoviridae Respirovlrus Rb Parainfluenza virus (type 2) PIV-2 ParsuTivxoviridae Rubulavirus Rb Parainfluenza virus (tvpe 3) PlV-3 Paramvxoviridae Respirovirus GP Parainfluenza virus (t^e 5) PIV-5 Paramvxoviridae Rubulavirus GRH

Parvovirus NS-1 NS-1 Parvoviridae Parvovirus M, R

Pnaumocvstis caiinil PCAR Pneumocvstidaceae Pneumocvstis R Pneumonia virus of mice PVM Paramvxoviridae Pneumovirus M. R, GP H

Polyoma virus POLY Polvomaviridae Polvomavirus M

Prospect Hill virus PHV Bunvaviridae Hantavirus M

Rabbit adenovirus RbAV Adenoviridae Mastadenovirus Rb Rabbit hemorrhaqic disease virus RHDV Caliciviridae Lagovirus Rb

Rabbit rotavinrs ROTA Reoviridae Rotavirus Rb

Rat coronavirus/sialodacrvoadentitis virus RCV, SDAV Coronaviridae Coronavirus R Rat cvtomegalovirus RCMV Herpesviridae Betaherpesvirus R

Rat minute virus RMV Parvoviridae Parvovirus R

Rat parvovirus RPV Parvoviridae Parvovirus R

Rat pr^vomavirus RatPvV2/RPvV2 Polvomaviridae Unclassified R Rat rotavirus finfectious diarrhea of infant rats) IDIR/ROTA-B Reoviridae Rotavirus R Rat theilovirus (Theiler's-like \nrus of rats) RTV Picomaviridae Theilovirus R

Reovirus REO Reoviridae Orthoreovirus M.R. GPH

Rabbit oicobirnavirus RPBV Picobirnaviridae Picobirnavirus Rb Sendai virus SEND Paramvxoviridae Respirovirus M.R. GRH

Seoul virus SEO Bunvaviridae Hantavirus M, R

Theiler's marine encephalomvelitis virus TMEV (GDVil) Picomaviridae Cardiovirus M.R

Toolan's H-1 virus H-1 Parvoviridae Parvowrus R

Toxoolasma aondii TOXO Sarcocvstidae Toxoolasma Rb Traoonema oaraluis-cuniculi TREP Spirochaetales Treoonema Rb

* Species: M = mouse, R = rat, GP = guinea pig, H= hamster, Rb = rabb/f, F = ferret, Z = zebrafish

Aaent Abbreviation Familv/Order Subfam/Genus Host Species Epstein-Barr virus EBV Herpesviridae Lvmphocrvptovirus Simian

Hepatitis A HEP-A Picomaviridae Heoatovirus Simian

Heroes B virus HBV Herpesviridae Alphaheroesvirus Simian Heroes virus paoio-2 HVP-2 Herpesviridae Alphahemesvirus Simian Lvmohocrvptovirus LCV Herpesviridae Lvmohocrvptovirus Simian Macaque (Rhesus) rhadinovirus MRV Herpesviridae Rhadinovirus Simian

Malaria (Plasmodium) MAL Piasmodiidae Plasmodium Simian

Measles virus MV Paramvxoviridae Morbillivirus Simian Parainfluenza virus (type 5) PIV-5 (SV-5) Paramvxoviridae Rubulavirus Simian Simian agent 6 SA-8 Herpesviridae Simplexvirus Simian Simian cvtomegalovirus SCMV/CMV Herpesviridae Cvtomegalovirus Simian

Simian foamy virus SFV Retrovlridae Soumavlnjs Simian

Simian immunodeficiencv virus SIV Retroviridae Lentivirus Simian

Simian rotavirus SA-11 Reoviridae Rotavirus Simian

Simian T-lvmohotropic virus STLV Retroviridae Deltaretrovirus Simian Simian tvoe D retrovirus SRV Retroviridae Betaretrovirus Simian Simian varicella virus SVV Herpesviridae Varicellovirus Simian Simian virus AO SV-AO Polvomaviridae Polvomavirus Simian Trvpanosoma cruii (Chaaas Disease) T. cruzilCHA Trypanosomatidae Trvpanosoma Simian

References

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