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What are the differences between Emtree and MeSH?

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What are the differences

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This document addresses the

following questions:

What are the differences between Emtree and MeSH?

How important are these differences to (potential) customers?

Why would customers choose Emtree instead of MeSH?

What do Emtree and MeSH have

in common?

Both are comprehensive biomedical / life science terminologies

Similar facet structure (Emtree was modeled on MeSH in 1988)

Both thesauri have broader/narrower terms and synonyms

Both have major annual updates with hundreds of new terms

Both are linked to CAS registry numbers and Enzyme Commission (EC) numbers

Emtree

MeSH

Emtree

benefits

for users

“Natural language terminology” (e.g. myeloid leukemia)

Has many “inverted terms” (e.g. leukemia, myeloid)

Intuitive and recognisable terms for ease of use

More than 270,000 synonyms (incl. over 175,000 drug synonyms)

Fewer synonyms (“entry terms”) than in Emtree

High probability that terms searched by users are in Emtree Includes all MeSH terms (many as

Emtree synonyms)

Emtree is easy for MeSH users to search

Relies upon “meaning” invested in terms by authors using them

Has many scope notes to describe how terms are used

No dependence on or need to look up scope notes

Larger (over 60,000 preferred terms)

Smaller (ca. 26,000 preferred terms)

Best chance of finding both drug and non-drug terminology Extensive drugs facet (over

30,000 preferred terms)

More limited drugs facet (ca. 8,800 preferred terms)

Drugs terminology is more up-to-date

New drug terms are updated earlier in Emtree

Drug terms are only updated when they become established

Best results for new drugs Polyhierarchical structure with

duplicated trees

Polyhierarchical structure with differences between trees

Unambiguous and context-free explosion searches

All drug and chemical information Detailed drug information is in a All the drug information you

What are Emtree’s plus points and why are they important?

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What plus points might users find

in MeSH?

MeSH has extensive history notes, which can be used to track earlier literature predating the introduction of particular terms.

MeSH has extensive scope notes. However, these include restrictions in term usage which users need to be aware of, as well as term definitions

MeSH has extensive terminology in nursing, veterinary medicine and dentistry (all of these terms are in Em tree, but many are synonyms).

Why choose Emtree instead of MeSH?

Emtree terminology:

• includes all of MeSH (i.e. all MeSH terms are mapped to Emtree).

• is readily extensible in response to user needs, subject to agreement with overall policy. • is optimally embedded into Elsevier’s platform (Embase.com)

In addition, Emtree drugs terminology is:

more extensive: with many synonyms (incl. many trade names) mapping to each drug term • up to date: with three updates each year, Emtree is especially suited for finding information on new drugs.

polyhierarchic: each drug is accessible from multiple points of view (e.g. structure, activity, therapeutic use).

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Drug Information Study

To illustrate the differences between Emtree and MeSH when searching for

(new) drugs, several drug searches were performed in Embase (indexed with

Emtree) and MEDLINE (indexed with MeSH).

Result: from 2-12 times more information is retrieved from Embase (see table).

Online study conducted on 26 July 2011, on Embase (www.embase.com) and MEDLINE (via PubMed).

1 Drugs were the top 10 leading products based on U.S. pharmaceutical sales

(source: Drug.com (http://www.drugs.com/top200.html)). Search period: literature publication years 2007 – July 2011.

Search method: each database was searched using the Emtree or MeSH preferred term as appropriate. Where MeSH lacked a preferred term, the NLM Supplementary Concept data were searched instead.

2 This MeSH term contains the Emtree term as a synonym (Emtree lists omeprazole as a different term) 3 Searched as Substance name from the NLM Supplementary Concept Data

4 Searched as MeSH preferred term

Product

name ¹

Search term

Citations

Emtree Preferred term MeSH Preferred termor Substance name Embase MEDLINE

Nexium esomeprazole omeprazole 2 2,092 1,003

Lipitor atorvastatin atorvastatin 3 9,452 1,597

Plavix clopidogrel clopidogrel3 15,342 2,446

Advair fluticasone propionate plus salmeterol fluticasone, salmeterol drug combination3 1,127 91

Oxycontin oxycodone oxycodone 4 3,547 373

Abilify aripiprazole aripiprazole 3 4,053 703

Singulair montelukast montelukast 3 2,314 399

Seroquel quetiapine quetiapine 3 6,254 696

Crestor rosuvastatin rosuvastatin 3 3,766 665

Cymbalta duloxetine duloxetine 3 3,099 457

Product

name ¹

Search term

Citations

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Database synopses

Embase:

Biomedical database produced by Elsevier

Comprehensive coverage of biomedicine with focus on drugs & pharmacology

Indexed with Emtree (over 60,000 Preferred Terms, including over 30,000 drugs and chemicals)

Over 25 million records from 1947-present; currently covers over 7,500 journals.

Covers all journals in MEDLINE together with 2,000 unique journals not in MEDLINE

Unique records are found especially in pharmacology journal titles and European literature

MEDLINE:

Biomedical database produced by NLM (U.S. National Library of Medicine)

Focus on all of biomedicine including nursing, dentistry and veterinary science

Indexed with MeSH (= Medical Subject Headings with over 26,000 MeSH Terms)

Over 19 million records from 1947-present; currently covers over 5,600 journals

All MEDLINE journals are included in Embase

More information

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E-Helpdesks e-mail addresses:

  EMEA: [email protected] APAC: [email protected] Americas: [email protected] Brazil: [email protected] Japan: [email protected]

For more information please visit:

References

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