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The Respiratory System

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Human Anatomy III:

Respiratory, Urinary & Digestive

Systems

The Respiratory System

 Major functions include:  Obtaining oxygen

 Removing carbon dioxide

 Maintenance of pH balance

 Respiration may be accomplished in a variety of ways

 Animals small enough use diffusion; no specialized organs

 Directly through the skin (again, via diffusion)

 Gills (for aquatic animals)

 Tracheal tubes (insects)

 Lungs (terrestrial vertebrates)

Clockwise from upper left: tracheae in a grasshopper; book lungs in a spider; tracheal gills in an aquatic insect larva

Basic Anatomy of the Respiratory

System I



Air enters through the

nose

Inside nose the air is warmed and moistened



From the nose it enters the

pharynx

Junction point where oral and nasal passages meet



It then passes over the

larynx

, or

voice

box

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Basic Anatomy of the Respiratory

System II

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The Alveoli

 Alveoli are the capillaries of the lung; gas exchange occurs here rather than in bronchi or bronchioles

 Oxygen moves out of the alveoli

 Carbon dioxide moves into the alveoli

 Alveoli resemble a bunch of grapes at the end of bronchioles

 Each alveolus is covered in a thin film of water and a surfactant

 Gas exchange can’t occur without water

 Surfactants keep an alveolus from sticking to itself and collapsing during breathing

The

Pleural Cavity

 The lungs sit within a space called the pleural cavity

 Normally, the outer surface of the lungs sticks to the inner surface of the pleural lining

 Puncturing the cavity causes a

pneumothorax  Air gets in and lungs

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4

Breathing:

Inspiration

 In the first part of breathing, air is taken into the lungs

 This is an active process and occurs when:

 The diaphragmis lowered

 The rib cage expands

 These two steps increase the lung volume, which lowers the pressure within the lungs compared to the outside pressure

 Thus, air moves in!

Breathing:

Expiration

 In the second part of breathing, air is pushed out of the lungs

 This is a passive process and occurs when:  The diaphragmis raised

 The rib cage contracts

 These two steps decrease the lung volume, which raises the pressure within the lungs compared to the outside pressure

 Thus, air moves out!

 Normal breathing rates in humans are 12-20 breaths per minute

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Respiration in Birds



Most vertebrates mix incoming and

outgoing air



Thus, some oxygen is lost and some

carbon dioxide retained



Birds have a unique breathing pathway

to avoid this

Air flows in only one direction



Involves a number of air sacs to store air

before or after it goes to lungs

Respiration in Fishes

 Most fish exchange gases primarily with gills (a few have lungs)

 Use counter-current exchangeto increase efficiency

 Water has less oxygen than does air

 Blood and water flow in opposite directions

The Urinary System

 Major functions are:

 To rid body of waste material, primarily excess water, excess ions, and nitrogenous waste

 To maintain fluid and ion balance

 To maintain pH balance

 To maintain blood volume

 In humans, ureais the nitrogenous waste product

 Formed when proteins are broken down

 The urinary system forms part of the excretory system, along with the lower part of the digestive system

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6

Basic Anatomy of the Urinary System

 Kidneyslie along the rear of the body, on

either side of the spine

 Kidneys filter the blood and produce a mix of water and waste called urine

 The ureteris a tube which connects the kidneys and…

 The bladderis a muscular storage organ which holds the urine

 Can hold up to 800 ml under normal conditions

 Urine leaves the bladder and exits the body through the urethra

 In males, urethra also connects to reproductive

organs; not true in females Most non-mammals have a common exit for the excretory and reproductive systems called the cloaca

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Urine Formation



Blood from capillaries is first filtered and

the resulting fluid collected (in the

glomerulus

and

Bowman’s capsule

)



This fluid moves through a series of tubes

(the

proximal and distal tubules

, the

loop

of Henle

)

Water and ions are reabsorbed as needed by diffusion or active transport

Capillaries around tubules gather up reabsorbed water and ions



Finally, fluid exits nephron and collects in

renal pelvis

Kidney Stones

 Stones result from a buildup of material in the renal medulla

 Usually made of calcium oxalate crystals

 If large enough (above 2-3 mm) cause pain as they move through ureter

 Usually painless after they reach bladder

Control of the Urinary System

 Several hormones control rate of water retention in the kidneys

 Most important of these is antidiuretic hormone, or ADH

 ADH increases reabsorption of water by making the tubules more “leaky”

 Diuretics, such as caffeine, can interfere with these hormones

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8

The Digestive System

 Major functions are:

 To break down large food particles and absorb nutrients

 To excrete solid waste material (feces)

 To help maintain water balance

 More primitive animals have a digestive system where food and wastes move through the same opening (the gastrovascular cavity)

 Most animals have a digestive system where food enters and wastes exit through separate openings (a complete digestive system)

The Journey of a Food Bolus!

 Digestion begins with the mouth

 Teeth mechanically break down large bites into small pieces

 Adult humans have 32 teeth

8 incisorsto cut or tear

4 cuspids(canines) for cutting

8 premolars(bicuspids) and 12 molarsfor crushing

 Carbohydrate breakdown begins due to amylase

produced by salivary glands

 After this, food moves into the pharynx via the process of swallowing

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The Journey of a Bolus II!

The Stomach

 Further breaks down food, mainly carbohydrates and proteins, to produce chyme

 Stomach possesses sphinctersat either end to prevent backflow into throat or early entry to intestines

 Cardiac (lower esophageal) sphincter to throat

 Pyloric sphincter to intestines

 Lining of stomach is heavily folded into rugae  Cells in rugae make hydrochloric acidand pepsin(an

enzyme to break down proteins

 pH of stomach is usually 2 (no food) to 4 (with food)

 Also produces amylases

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10

The

Pancreas

 Lies near the stomach and connects to duodenum

 Produces a large amount of digestive enzymes which enter small intestine

 Amylases for carbohydrates

 Proteases for protein

 Lipases for lipids (fats)

 Also produces the hormones insulin and glucagon, which help regulate blood sugar levels

The

Liver

 Largest organ by weight in the body

 Produces bile, which is stored in the gall bladder

or enters SI

 Bile helps break apart fat globules so that lipase can act on them to break them down

 Converts and stores simple sugars to regulate blood sugar level

 Completes breakdown of proteins to amino acids and urea

 Removes toxins from blood

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Liver is made up of around 100,000 lobules, which filter blood from intestines

The

Large Intestine

 Thicker and shorter (~1.5 m) than small intestine

 Aids in reabsorption of water

 About 95% of water entering intestines is reabsorbed

 Absorption of some material  Assisted by a dense gut flora (bacteria)

 These also produce several vitamins (K, B5)

 Compaction and excretion of solid waste material

 Largest segment is the colon

 Cecumis a pouch-like region that attaches to small intestine

 Rectumis the muscular tube that exits body at the anus

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