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Pitx2 promotes development of splanchnic mesoderm derived branchiomeric muscle

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Figure

Fig. 1. Pitx2 is required for survival of branchiomeric muscleprecursors. (A,B) Right and left views of 9.5 dpc mouse embryos afterwhole-mount in situ hybridization with a Pitx2 probe (arrows denotehybridization signal)
Fig. 2. Defectivespecification of firstbranchial archundifferentiated coremesoderm in Pitx2 mutants.A-C) Myogenin and (D,E)
Fig. 3. Specified, Myf5-positive myoblasts are drastically reducednull
Fig. 5. Splanchnic mesoderm-derived Mef2cAHFcreand the R26R allele indicated that the mesoderm lineage contributes to first branchial arch branchiomericmuscle (denoted by arrows)
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