[123I]FP-CIT-SPECT
![Clinical evaluation of [123I]FP-CIT SPECT scans on the novel brain-dedicated InSPira HD SPECT system: a head-to-head comparison](data:image/gif;base64,R0lGODlhAQABAIAAAP///wAAACH5BAEAAAAALAAAAAABAAEAAAICRAEAOw==)
Clinical evaluation of [123I]FP-CIT SPECT scans on the novel brain-dedicated InSPira HD SPECT system: a head-to-head comparison
... brain-dedicated SPECT scanner, allows for imaging with a high spatial ...[123I]FP-CIT SPECT scans were visually ...[123I]FP-CIT SPECT imaging can be ...
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Imaging of serotonin transporters with [123I]FP-CIT SPECT in the human hypothalamus
... using SPECT with the ligand [ 123 I]FP-CIT, which has a high affinity for the dopamine transporter and somewhat lower affinity for the ...the SPECT imaging. Acquisition of the SPECT ...
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The impact of reconstruction and scanner characterisation on the diagnostic capability of a normal database for [123I]FP-CIT SPECT imaging
... In recent years, the Neuroimaging Committee of the European Association of Nuclear Medicine put together a multi-centre group to create a substantial database of normal healthy control subjects with [ 123 ...
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Reliability of visual assessment by non-expert nuclear medicine physicians and appropriateness of indications of [123I]FP-CIT SPECT imaging by neurologists in patients with early drug-naive Parkinson’s disease
... I]FP-CIT SPECT images were classified as either “normal” or ...DAT SPECT imaging was characterized by clear binding of the radio- tracer in the putamen and caudate nuclei both bilaterally, ...
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Dopamine transporter imaging with [18F]FE-PE2I PET and [123I]FP-CIT SPECT—a clinical comparison
... and FP-CIT was represented in one HC who had relatively low DAT binding with FE-PE2I especially in the caudate, but nor- mal FP-CIT ...to SPECT imaging in which the spatial resolution ...
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Standardized Semi Quantitative Evaluation of [123I]FP CIT SPECT in a Multicenter Study
... Few multicenter trials about [123I]FP-CIT are avail- able, and among them none followed a semi-quantitative approach [3,6]. In fact, these papers showed a good per- formance of visual assessment. ...
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No difference in striatal dopamine transporter availability between active smokers, ex-smokers and non-smokers using [123I]FP-CIT (DaTSCAN) and SPECT
... Tc]TRODAT-1 SPECT studies and the results of our study and the study of Staley et ...TRODAT-1 SPECT studies) and possibly the imaging properties of [ 99m Tc]TRODAT-1 related to a small ratio between binding ...
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The predictive value of transcranial duplex sonography for the clinical diagnosis in undiagnosed parkinsonian syndromes: comparison with SPECT scans
... tremor; FP-CIT: 123I-Ioflupane; IPD: idiopathic Parkinson's disease; IBZM: 123I-iodobenzamide; MSA: multiple system atrophy; NPV: negative predictive value; PPV: positive predictive value; ...
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[123I]FP-CIT ENC-DAT normal database: the impact of the reconstruction and quantification methods
... Ultimately, the results of this study are representative of the on-going struggle be- tween robustness and accuracy in SPECT imaging. The determination of an accurate SBR would require attenuation, scatter and ...
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Computer-aided diagnosis for (123I)FP-CIT imaging: impact on clinical reporting
... In this study, the PPMI test data was deliberately skewed towards more difficult cases in order to maxi- mise the opportunity for CADx to influence results. This was necessary because of the strict patient group defini- ...
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Süßmair, Christine (2007): Neue Methoden in der Diagnostik von Parkinson-Syndromen mit SPECT. Dissertation, LMU München: Medizinische Fakultät
... von SPECT-Untersuchungen des dopaminer- gen Systems basiert auf einer validen Angleichung des Patientendatensatzes, dem soge- nannten Fitting, an das im Vorabschnitt beschriebene ...
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Comparison of machine learning and semi-quantification algorithms for (I123)FP-CIT classification: the beginning of the end for semi-quantification?
... Considering that (I123)FP-CIT is a low volume test, used on relatively few clinical patients, the investment required to develop a new clinical reporting tool and pass necessary regulatory hurdles (such as ...
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Impact of the cerebrospinal fluid-mask algorithm on the diagnostic performance of 123I-Ioflupane SPECT: an investigation of parkinsonian syndromes
... This single-center retrospective study included 529 consecutive patients who underwent DAT SPECT from February 2014 to May 2017. Of these patients, 208 were ex- cluded from the study on account of having ...
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Practice Parameter: Diagnosis and prognosis of new onset Parkinson disease (an evidence-based review)Report of the Quality Standards Subcommittee of the American Academy of Neurology
... Drug challenge: Stimulation of growth hormone (GH) with clonidine. The ability of clonidine, a cen- trally acting ␣ 2 adrenergic receptor agonist, to stim- ulate the release of GH has been proposed as a method to ...
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Quantitative evaluation using single-photon emission computed tomography with acetazolamide is reliable for preoperative evaluation before cardiac surgery in severe carotid intracranial artery stenotic and/or occlusive disease: a case report
... circulation, SPECT is the most useful method for quantification of cerebral blood flow ...perfusion SPECT, particularly with use of acetazol- amide, is considered capable of detecting hemodynamic compromise ...
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Fabritius, Arne (2016): Novel genetically encoded biosensors for cGMP. Dissertation, LMU München: Fakultät für Biologie
... A) Two fluorescent proteins (FP I and FP II) are fused via a sensor domain (SD). In the unbound state the donor FP transfers energy to the acceptor FP. Upon ligand binding a conformatio[r] ...
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TWIN DEFICITS THREAT IN THE EUROPEAN UNION
... defi cit hypothesis based on assumption that budget defi cit implies current account defi cit in the case of the Netherlands, Greece, Italy, Portugal, Cyprus, Czech Republic, and ...
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Practice developments and educational requirements in hybrid imaging
... • Initial Hybrid SPECT/ CT systems provided AC / nondiagnostic images localisation • Role of hybrid SPECT/CT systems has evolved • Possible to undertake diagnostic CT on all modern SPECT[r] ...
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Interactions between nuclear factors and the hepatitis B virus enhancer.
... These are the nuclear factor NF-1 binding site FP-I, the SV40 enhancer core element FP-II and FP-VI, the polyomavirus enhancer factor EF-C element FP-III, and the hepatocyte nuclear fact[r] ...
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123I-labeled metaiodobenzylguanidine for diagnosis of neuroendocrine tumors
... Thus, MIBG can be taken up by NETs, in particular by catecholamine-secreting tumors such as neuroblastomas (NBs), pheochromocytomas, paragangliomas, endocrine tumors of t[r] ...
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