2-OXOINDOLIN-3-YLIDENE
Extractive Spectrophotometric Determination of Osmium (IV) Using 2-(5-Bromo-2-Oxoindolin-3-Ylidene) Hydrazine Carbothioamide as an Analytical Reagent
... using 2-(5-Bromo -2-Oxoindolin-3- ylidene)Hydrazine Carbothioamide or HBITSC as an analytical reagent HBITSC has been synthesized and characterized by elemental and spectral ...3cm ...
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Synthesis of novel N -(2-oxoindolin-3-ylidene)benzofuran-2-carbohydrazides via greener approach and their biological activities
... We have successfully synthesized ten novel N′-(2-oxoindolin-3-ylidene)benzofuran-2-carbohydrazides (5a-j) in good yields using green chemistry. The structures of all the compounds were ...
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A theoretical analysis of the inhibition of the VEGFR-2 vascular endothelial growth factor and the anti-proliferative activity against the HepG2 hepatocellular carcinoma cell line by a series of 1-(4-((2- oxoindolin-3-ylidene)amino)phenyl)-3-arylureas
... An analysis of the relationships between electronic structure and the inhibition of the kinase activity of VEGFR-2 was carried out for a series of ...
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SYNTHESIS OF 1 SUBSTITUTED 2 [2 (4, 5/5, 6/5, 7 DIMETHYL) 2 OXOINDOLIN 3 YLIDENE) HYDRAZINYL] 3 PHENYLQUINAZOLIN 4(3H) ONES AS ANTIFUNGAL AGENTS
... gave 2- hydrazinyl-3-phenylquinazolin-4(3H)-one (2) which in turn was obtained by the reaction of 2-aminobenzoic acid with ...phenylisothiocyanate. 2- ...
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Synthesis and Analgesic Activity of 1-(1-((Substituted) Methyl)-5- Methoxy-2-Oxoindolin-3-Ylidene)-4- (Substituted Pyridin-2-Yl)Thiosemicarbazide
... Synthesis of compound (4a-4j): A slurry consisting of 1-(5-methoxy-2-oxoindolin-3-ylidene)-4- (substituted pyridin-2-yl) thiosemicarbazide (0.002 mol), THF (3ml) and 37% formalin (1ml) ...
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Structural optimization and evaluation of novel 2-pyrrolidone-fused (2-oxoindolin-3-ylidene)methylpyrrole derivatives as potential VEGFR-2/PDGFRβ inhibitors
... of 2-pyrrolidone-fused (2-oxoindolin-3-ylidene)methylpyrrole were critical for VEGFR-2 inhibitory ...C(5)-SO 2 N(CH 2 CH 2 Cl) 2 and the NH of the ...
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Extractive and spectrophotometric determination of Iridium(III)using 2 (5 bromo 2 oxoindolin 3 ylidene) hydrazinecarbothioamide as an analytical reagent
... [1-15]. 2-(5- bromo-2- oxoindolin- 3-ylidene) hydrazine carbothioamide, [HBITSC] has been used for the development of extractive spectrophotometric methods for the determination of ...
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Synthesis, Characterization and Study of Microbiological Activity of Iridium (III) Complex with, 2-(5- Bromo-2- Oxoindolin-3-Ylidene) Hydrazine Carbothioamide
... In the present paper, complex of Ir(III), with Schiff base ligand derived from 5- Bromoisatin and thiosemicarbazide, [2-(5-Bromo -2-Oxoindolin-3-ylidene) Hydrazine Carbothioamide], ...
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NOVEL 2 – AMINO – N’ – (2 OXOINDOLIN – 3 – YLIDENE) BENZO [d] OXAZOL – 5 CARBOHYDRAZIDES AS ANTI INFLAMMATORY AGENTS
... All the experiments were carried out using male, Sprague-Dawley rats (300-350 g) were obtained from animal house, UCPSc, Kakatiya University, Warangal, India. On arrival the animals were placed at random and allocated to ...
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Synthesis and pharmacological evaluation of 6 hydroxy 2,5,7,8 tetramethyl N' (2 oxoindolin 3 ylidene)chroman 2 carbohydrazide derivatives as antimicrobial agents
... All synthesized compounds were preliminary evaluated for their in vitro antimicrobial activity by the Agar well diffusion and serial tube dilution method [11]. Antimicrobial activity was measured against tested ...
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ANTIDIABETIC ACTIVITY OF 1 (4 (DIMETHYLAMINO)BENZYLIDENE) 5 (2 OXO INDOLIN 3 YLIDENE) THIOCARBOHYDRAZONE IN RATS
... Objective: The present study was aimed to evaluate the antidiabetic activity of 1-(4-(Dimethylamino) benzylidene)-5-(2-oxoindolin-3- ylidene) thiocarbohydrazone i.e. a novel Isatin derivative ...
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1 (5 Bromo 2 oxoindolin 3 ylidene) 4 phenylthiosemicarbazide
... For the pharmacological properties of isatin-thiosemi- carbazone derivatives against cruzain, falcipain-2 and rhode- sain, see: Chiyanzu et al. (2003). For the synthesis of 5- ...
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Crystal structure of (Z) 2 (5 fluoro 2 oxoindolin 3 ylidene)hydrazinecarbothioamide
... For one of the first reports of the synthesis of thio- semicarbazone derivatives, see: Freund & Schander (1902). For the synthesis and crystal structure of a similar compound, namely ...
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Utility of 4 (isatin 3 ylideneamino)benzohydrazide in the synthesis of bioactive N heterocyclic compounds
... gave5,6,7,8-tetrabromo-2-[4-(2- oxoindolin-3-ylidene- amino)benzoyl]-2,3-dihydrophthalazine-1,4-dione ...of 3 with active methylene group containing-compounds namely; diethyl ...
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1 (5 Bromo 2 oxoindolin 3 ylidene)thiosemicarbazone
... For the pharmacological properties of isatin-thio- semicarbazone derivatives against cruzain, falcipain-2 and rhodesain, see: Chiyanzu et al. (2003). For the synthesis of 5- bromoisatin-3-thiosemicarbazone, ...
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2 (1 Methyl 2 oxoindolin 3 ylidene)malononitrile
... precipitated 2-(1-methyl-2-oxoindolin-3-ylidene)malononitrile was filtered off and washed with 40 ml portions of aceto- nitrile, and the combined filtrates were concentrated under ...
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Hirshfeld analysis and molecular docking with the RDR enzyme of 2 (5 chloro 2 oxoindolin 3 ylidene) N methylhydrazinecarbothioamide
... Methods for the synthesis of isatin derivatives were first reported in the first half of the 19th century (Erdmann, 1841a,b; Laurent, 1841), while for thiosemicarbazone deriva- tives one of the first reports can be ...
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2 (3 Cyano 4 {3 [1 (2 hydroxyethyl) 3,3 dimethyl 1,3 dihydroindol 2 ylidene]prop 2 enyl} 5,5 dimethyl 5H furan 2 ylidene)malononitrile
... Data collection: APEX2 (Bruker, 2008); cell refinement: SAINT (Bruker, 2008); data reduction: SAINT; program(s) used to solve structure: SHELXS97 (Sheldrick, 2008); program(s) used to refine structure: SHELXL2012 ...
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Experimental and Quantum Chemical Studies on the Corrosion Inhibition Potentials of 2-(2-Oxoindolin-3-Ylideneamino) Acetic Acid and Indoline-2,3-Dione
... The fact that the adsorption of IG and IS on mild steel surface proceeded via chemical adsorption indicate that the mechanism is consistent with the transferred of electron from the inhibitor’s molecule to the empty ...
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Crystal structure of (E) 1,3 dimethyl 2 [3 (3 nitrophenyl)triaz 2 en 1 ylidene] 2,3 dihydro 1H imidazole
... In the crystal, the independent molecules are linked by C— H O hydrogen bonds forming –A–A–A– and –B–B–B– chains along [100]. The chains are linked by C—H O and C—H N hydrogen bonds, forming sheets lying parallel to ...
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