2-Pyrazoline derivatives
Synthesis, Characterization and Evaluation of Analgesic, Anti Inflammatory, Ulcerogenic Potential of Some 2 Pyrazoline Derivatives
... thiophene derivatives also possess analgesic [30-33] and anti-inflammatory [34-36] ...synthesize 2-pyrazoline derivatives containing pyridyl/napthyl, furyl/thienyl/4-nitrophenyl and ...
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Synthesis, characterization and antimicrobial studies of novel 2- pyrazoline derivatives
... A simple, efficient method for the synthesis of some novel 2-pyrazoline derivatives is reported.Pyrazolines were prepared by condensing chalcones with hydrazine hydrate /isoniazid / ...
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Synthesis, characterization and antibacterial evaluation of novel 2 pyrazoline derivatives
... substituted)-1-thioamide-2-pyrazoline derivatives (4a-4e) were synthesized by reacting substituted 1-(β-picolinoylaminoazo)-3- benzylidene propan-2-one derivatives (3a-3e) with ...
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SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVOLUTION OF SOME NOVEL 2 PYRAZOLINE DERIVATIVES WITH CHALCONE
... the 2-pyrazoline and chalcone together for enhancing biological ...the pyrazoline moiety almost equally contributes to the anti-microbial activity comparable with that of standard drugs ...the ...
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Synthesis and antimicrobial activity of novel 1 thiocarbamoyl 2 pyrazoline derivatives
... nitrogens. 2-Pyrazolines are widely studied by medicinal chemists and are considered as cyclic hydrazine moiety ...[2]. Pyrazoline derivatives possess variety of biological action such as ...
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Synthesis, Antitubercular, Anticonvulsant and Antiinflammatory Activities of Some Novel 2-Pyrazoline Derivatives
... the derivatives possesses all three ...new 2-Pyrazoline ...of 2-CH 3 , 4-NH 2 in phenyl ring at 5-position of pyrazoline ring of newly synthesized ...
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MICROWAVE ASSISTED SYNTHESIS AND CHARACTERIZATION OF NEW 2-PYRAZOLINE DERIVATIVES
... new pyrazoline derivatives. Pyrazoline formation between the chalcone (3a) derived from acetophenone and 4-methyl benzaldehyde with furan-2- carboxylicacid hydrazide was studied as a model ...
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Novel 2-pyrazoline derivatives as potential antibacterial and antifungal agents
... 3072.4 (C-H). (1-(4-ß uorophenyl)-3-(4-ß uorophenyl)- 2-propen-1-one) (0.05 mol) was added to isoniazid (0.1 mol) in a 100 ml R.B.F. containing 30 ml of N, N-dimethylformamide. The mixture was refluxed at 120° to ...
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PYRAZOLINE DERIVATIVES: A WORTHY INSIGHT INTO THE RECENT ADVANCES AND POTENTIAL PHARMACOLOGICAL ACTIVITIES
... 2-Pyrazolines display a broad spectrum of potential pharmacological activities and are present in a number of pharmacologically active molecules such as phenazone/ amidopyrene/ methampyrone (analgesic and ...
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SYNTHESIS OF SOME 3, 5 DIPHENYL ∆1 –PYRAZOLINE AND 5 (2′′ FURYL) ∆1 PYRAZOLINE DERIVATIVES AND THEIR SCREENING FOR ANTIDEPRESSANT AND ANTICONVULSANT ACTIVITY
... 5-diphenyl-2- pyrazoline derivatives and 5-(2'-furyl)-2-pyrazoline derivatives have been synthesized¸ and then evaluated for their antidepressant and anticonvulsant ...
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Synthesis and evaluation of some pyrazoline derivatives as anticancer agents
... Pyrazolines are one of the heterocyclic compounds with very important biological activities. Pyrazoline carbaldehydes were synthesized using chalcones and hydrazine hydratein presence of formic acid. The ...
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Synthesis and estimations of antimicrobial properties of novel pyrazoline derivatives
... novel pyrazoline compound shows considerable antimicrobial activity against tested bacteria and fungi species comparatively with standard used in ...synthesized pyrazoline derivatives will be having ...
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Synthesis and Antibacterial Evaluation of Some Novel Pyrazoline Derivatives
... Hz) , 2.97 (dd, 1H, J = 16.4 & 7.8 Hz), 3.25 (dd, 1H, J = 15.8 & 8.0 Hz), 3.76 (s, 3 H), 3.91 ( s, 3 H), 4.01 (t, 2 H, J = 6.8 Hz), 5.56 (dd, 1H, J = 14.2 & 7.8.0 Hz), 6.76 ( d, 1H, J = 6.8 Hz) 6.92 ...
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SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL PYRAZOLINE AND ISOXAZOLINE DERIVATIVES
... performed in Mueller-Hinton broth medium at a pH of 7.2 with an inoculum of (1-2) × 10 3 cells/mL by the spectrophotometric method and an aliquot of 100μL solution was added to each tube of serial dilution. The ...
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FUSED HETEROCYCLES AS A POTENT BIOLOGICAL AGENTS; RECENT ADVANCEMENT
... Many combinations of fused heterocyclic structures can be designed, to develop new chemical entity with versatile physical, chemical and biological properties. The rationale of fusion involve geometrically rigid ...
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SYNTHESIS AND ANTIMICROBIAL SCREENING OF NEW PYRAZOLINES DERIVED FROM CHALCONES OF VANILLIN ANALOG
... pyrazoline ring contains N–N bond linkage and acetylpyrazoline ring contains N-N-CO moiety which is considered to be the key factor in their biological actions. In natural compounds having N–N bonds is rare ...
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Synthesis and Spectral Characterization of Novel 2 Pyrazoline and Bis 2 Pyrazoline Containing Quinoline Moiety
... This quinoline nucleus is an important class of heterocyclic structure found in many synthetic and natural occurring products with a wide range of pharmaco- logical activities [1], such as antiviral [2], ...
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[1 (4 Nitrobenzyl) 2 butyl 4 chloro 1H imidazol 5 yl] 4, 5 dihydro 1 phenyl 1H pyrazole: Synthesis, Anti Inflammatory and Analgesic Activities
... hydrazones 2 were prepared according to the literature procedure ...hydrazone 2 by chlo- ramine-T trihydrate afforded nitrile imines, which was intercepted in situ by different alkenes 3a-h in refluxing ...
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Ultrasound-assisted Synthesis of Some New Curcumin Analogs and Their Corresponding Pyrazoline Derivatives
... The structures of the synthesized compounds (3a-e) were assigned on the basis of spectral data. In the IR spectra Table IV, the appearance of a sharp band at 3320/cm attributed to N-H stretching vibration, strong bands ...
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Synthesis and Biological Evaluation of Substituted Pyrazoline Derivatives Bearing 3,4,5 Trimethoxyphenyl Moiety as Anticancer, Anti inflammatory and Antioxidant Agents
... NO radical scavenging activity carried out as per the reported method [29]. Nitric oxide radicals generated from sodium nitroprusside solution. 1 ml of 10 mM sodium nitroprusside mixed with 1 ml of 1 mM synthesized ...
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