20(S)-ginsenoside Rg3
Evaluation of Antifatigue Effects of 20(S)-Ginsenoside Rg3 in Forced Swimming Mice
... of 20(S)-ginsenoside Rg3 using forced swimming test in ...three 20(S)-ginsenoside Rg3-treated ...of 20(S)-ginsenoside Rg3 (10, 20 ...
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20(S)-ginsenoside Rg3 promotes senescence and apoptosis in gallbladder cancer cells via the p53 pathway
... prognosis. 20(S)-ginsenoside Rg3 (20(S)- Rg3) is a steroidal saponin with high pharmacological ...of 20(S)-Rg3 in human GBC has not yet been ...that ...
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Original Article 20(S)-ginsenoside Rg3 protects myocardium by inhibiting AGE-RAGE-mediated oxidative stress in diabetic rats
... of 20(S)-gin- senoside Rg3 on diabetes-related myocardial ...with 20(S)-ginsenoside Rg3 for 12 ...with 20(S)-ginsenoside Rg3 resulted in an ...
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<p>20(R)-Ginsenoside Rg3 Influences Cancer Stem Cell Properties and the Epithelial-Mesenchymal Transition in Colorectal Cancer via the SNAIL Signaling Axis</p>
... 11 Ginsenoside Rg3, a protopanaxadiol-type ginsenoside, is a pharmacologically and physiologically active natural constituent of ginseng that has been demonstrated to exert various biological ...
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Ginsenoside Rg3 attenuates hepatoma VEGF overexpression after hepatic artery embolization in an orthotopic transplantation hepatocellular carcinoma rat model
... Immunohistochemistry (IHC) was performed on formalin- fixed, paraffin-embedded tumor tissue sections of 5 µ m thick- ness. These specimens were dewaxed at 55 ° C for 30 minutes and washed in PBS three times for 3 ...
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Original Article Effects of ginsenoside Rg3 combined with 125 I seeds on serum TGF-α, TGF-β1, and VEGF in patients with medium and advanced non-small cell lung cancer
... Short-term curative effects were compared be- tween the two groups using the therapeutic evaluation criteria of solid tumors as follows: Complete remission (CR), partial remission (PR), stable disease (SD), and ...
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Original Article Suramin combined with ginsenoside Rg3 alleviates cascular lesions and adventitial inflammation in venous allografts
... while ginsenoside Rg3 may rely on its anti-apoptotic and anti-inflammatory phar- macological effects to improve myocardial isch- emia-reperfusion damage ...senoside Rg3 pretreatment attenuates acet- ...
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Additive antiangiogenesis effect of ginsenoside Rg3 with low-dose metronomic temozolomide on rat glioma cells both in vivo and in vitro
... ginseng, ginsenoside Rg3 (RG3) is the protopanaxadiol type of dammarane ginsenoside consisting of characteristic genuine aglycone moieties ...[20]. RG3 has multiple functions in ...
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Original Article Ginsenoside Rg3 inhibits HIF-1α and VEGF expression in patient with acute leukemia via inhibiting the activation of PI3K/Akt and ERK1/2 pathways
... were 20-60 years of age with expected survival time longer than 3 months, normal function in the liver, kidney and heart, and without other severe ...two Rg3 tablets twice a day for 2 ...
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<p>Ginsenoside Rg3 protects mouse leydig cells against triptolide by downregulation of miR-26a</p>
... of Rg3 was indicated in Figure ...of Rg3 or TP on the viability of MLTC-1 ...M Rg3 signi fi cantly inhibited the proliferation of MLTC-1 cells, whereas 5, 10, 20 or 40 μ M Rg3 had no ...
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Clinical benefit from EGFR-TKI plus ginsenoside Rg3 in patients with advanced non-small cell lung cancer harboring EGFR active mutation
... and ginsenoside Rg3 before 2012 and the observation after 2015 was not long enough to do statistic ...of ginsenoside Rg3 and special types of EGFR mutation, such as exon 20 mutation, ...
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Original Article Ginsenoside Rd pretreatment attenuates apoptosis of PC12 cells induced by oxygen-glucose deprivation
... neuronal apoptosis. This is an important cause of motor function impairment after SCII. Two types of anoxic cell models have been used in in vitro experiments [18]. One is a physical anoxic model created by a hypoxia ...
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Neuroprotective effect of panax notoginseng saponins and its main components
... Ginsenoside-Rb1 is a main monomer of PNS. Rb1 can decrease the degree of cerebral edema, improve neuro- behavioral score, protect vascular system from thicken- ing and spasm [17], inhibit lipid peroxidation in the ...
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Biotransformation of ginsenoside Rb1 via the gypenoside pathway by human gut bacteria
... The medium was prepared according to our previous re- port [33]. Briefly, 100 mL of autoclaved BHI medium (3.7 g/100 mL) was supplemented with 0.05 mg of vitamin K1, 0.5 mg of bovine hemin, and 50 mg of L-cystine. The ...
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<p>Assessment of a New Ginsenoside Rh2 Nanoniosomal Formulation for Enhanced Antitumor Efficacy on Prostate Cancer: An in vitro Study</p>
... niosomal Ginsenoside Rh2 to deliver drugs to the PC3 prostate cancer cell ...line. Ginsenoside Rh2 loading up to ...of Ginsenoside Rh2-loaded niosome (containing 5% DOTAP) demonstrated no significant ...
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Biotransformation of ginsenosides Rb1, Rg3 and Rh2 in rat gastrointestinal tracts
... MS experiments were performed on a quadruple-time of flight (Q-TOF) tandem mass spectrometer API Q- STAR Pulsar I (Applied Biosystems, USA). Negative or positive ion mode in electrospray ionization (ESI) was used to ...
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combined with 5-fluorouracil on HCT-116 cell
... obviously inhibited cell viability, induced apop- tosis and inhibited PI3K/Akt signaling pathway on A549, H23 cells [16]. Its anti-angiogenesis along with anti-cancer effects have been shown in several cancers [17-19]. ...
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Original Article Pharmacokinetic study on ginsenoside Rg
... HPLC analyses were performed using a WATERS (model Aliance e2695) High Performance Li- quid chromatograph (HPLC) system. HPLC sep- aration was achieved using an Agilent Eclipse XDB-C18 column (4.6 mm × 150 mm, 5 µm ...
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Effects of short-term temperature change in the innocuous range on histaminergic and non-histaminergic acute itch
... 40 s each (Experiment 1: 13 cycles, Experiment 2: 12 ...lasted 20 s, with tem- perature change occurring at the end of each block at a rate of ...occurred 20 s after itch application ...
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Ginsenoside Re: Its chemistry, metabolism and pharmacokinetics
... Gu S, Shang L, Zheng C: Simultaneous determination of ginsenoside Rg1, Re, Rd, Rb1 and ophiopogonin D in rat plasma by liquid chromatography/electrospray ionization mass spectrometric method and its ...
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