3′:5′-cyclic monophosphate (cAMP)
STATI, STAT6 and Adenosine 3′,5′-Cyclic Monophosphate (cAMP) Signaling Drive SOCS3 Expression in Inactive Ulcerative Colitis
... moter that drive transcription of the gene can already provide important clues as to mechanisms potentially involved here. The SOCS3 promoter contains two puta- tive STAT-response elements (SREs): a GC-rich region and an ...
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Renal effects of adenosine 3′,5′ cyclic monophosphate and dibutyryl adenosine 3′,5′ cyclic monophosphate: Evidence for a role for adenosine 3′,5′ cyclic monophosphate in the regulation of proximal tubular sodium reabsorption
... adenosine 3¢,5¢-cyclic monophosphate (cyclic AMP) in the left renal artery decreased ipsilaterally glomerular filtration rate (GFR), cortical and non-cortical renal plasma flow, and ...
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Decreased cerebrospinal fluid cyclic adenosine 3',5' monophosphate in bacterial meningitis
... Since the concentration of cAMP in the cerebrospinal fluid is normally found to be within narrow limits and probably reflects intracellular cAMP levels, the results described in this stu[r] ...
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Ultra-high field MR angiography in human migraine models: a 3.0 T/7.0 T comparison study
... of cyclic guanosine monopho- sphate (cGMP) which ultimately leads to relaxation of vascular smooth muscle ...in cyclic adenosine monophosphate (cAMP) ...
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Leptin interferes with 3',5'-Cyclic Adenosine Monophosphate (cAMP) signaling to inhibit steroidogenesis in human granulosa cells
... Studies of human ovarian granulosa cells have been lim- ited by the small numbers and short life span in culture of cells currently obtained from clinical material. Using SV40 large T antigen, we have reproducibly ...
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Deletion of the α subunit of the heterotrimeric Go protein impairs cerebellar cortical development in mice
... Calbindin-D28K; cAMP: Cyclic AMP, 3 ′ ,5 ′ -cyclic adenosine monophosphate; CB1: Cannabinoid receptor 1; CFs: Climbing fibers; CNS: Central nervous system; DCN: Deep cerebellar ...
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Active Potassium Transport by the Isolated Lepidopteran Larval Midgut: Stimulation of Net Potassium Flux and Elimination of the Slower Phase Decline of the Short Circuit Current
... Adenosine 3':5'-cyclic monophosphate cyclic AMP, Antibiotic A23187, caffeine, cholera toxin, dibutyryladenosine 3' :5'-cyclic monophosphate dbcAMP, 5-hydroxytryptamine 5-HT, larval blood[r] ...
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The content and metabolism of cyclic adenosine 3', 5' monophosphate and cyclic guanosine 3', 5' monophosphate in adenocarcinoma of the human colon
... that cyclic AMP and cyclic GMP may be important determinants of cell growth and ...examined cyclic nucleotide content and metabolism in naturally occurring tumors of ...compared cAMP and cGMP ...
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Study of the Renal Tubular Interactions of Thyrocalcitonin, Cyclic Adenosine 3′, 5′ Monophosphate, 25 Hydroxycholecalciferol, and Calcium Ion
... phosphate, calcium, sodium, and potassium by the kidney. The infusion of 25HCC in a dosage of 60 U/h to moderately saline-expanded animals (2.5% body weight) induced a fall in the excretion of all of the ions under study ...
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Interaction of nitric oxide and cyclic guanosine 3',5' monophosphate in erythropoietin production
... monophosphate (cGMP). Serum levels of EPO in ex-hypoxic polycythemic mice were significantly increased after injections of 200 micrograms/kg sodium nitroprusside for 4 d. One injection of NG-nitro-L-arginine ...
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The effect of polystyrene beads on cyclic 3′,5′ adenosine monophosphate concentration in leukocytes
... in cyclic AMP ...in cyclic AMP levels. There was no change in cyclic AMP content of rabbit alveolar macrophages or guinea pig PMN during phagocytosis of polystyrene ...increase cyclic AMP ...
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Cyclic 3′,5′ adenosine monophosphate in human blood platelets: II Effect of N6 2′ 0 dibutyryl cyclic 3′,5′ adenosine monophosphate on platelet function
... Dibutyryl cyclic AMP inhibited platelet aggregation induced by ADP, epinephrine, collagen, and ...thrombin. Cyclic AMP was also inhibitory but was less ...factor 3 activity and of the release of ...
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Control and localization of rat adrenal cyclic guanosine 3', 5' monophosphate Comparison with adrenal cyclic adenosine 3', 5' monophosphate
... Adrenal cyclic GMP levels rise in acutely hypophysectomized rats to a maximum at 1 h of approximately 200% of control levels; there is a return to base line at 4-12 h after ...adrenal cyclic AMP falls ...
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Glucagon-like peptide-1 enhances cardiac L-type Ca2+ currents via activation of the cAMP-dependent protein kinase A pathway
... During 37°C digestion, Ca 2+ -free enzymatic solution containing trypsin was gradually replaced with another enzymatic solution containing 0.1 mM of Ca 2+ , 0.075% collagenase, 0.1% soybean trypsin inhibitor, and 0.2% ...
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The effect of the novel phosphodiesterase-4 inhibitor MEM 1414 on the allergen induced responses in mild asthma
... from 3–10 hours, AUC 3–10 h) between MEM 1414 and placebo with 80% power, assuming a within subject standard de- viation of 50% and a 2-sided alpha significance level of ...from 3–10 hours (AUC ...
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Hypothalamus-adipose tissue crosstalk: neuropeptide Y and the regulation of energy metabolism
... and cyclic AMP (cAMP) production. Decreased cellular cAMP levels inhibit protein kinase A (PKA), which phosphorylates and activates hormone-sensitive lipase ...the cAMP-PKA pathway-associated ...
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Pulmonary vascular and right ventricular dysfunction in adult critical care: current and emerging options for management: a systematic literature review
... The gold standard for the diagnosis and management of PH and RV dysfunction in the ICU setting is con- sidered by some to be through pulmonary artery cathe- terization (PAC), even though most of the information can be ...
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Modulation of airway hyperresponsiveness by rhinovirus exposure
... Primary airway cell culture and precision cut lung slices (PCLS) are currently used to study effects of a number of lung insults ex vivo (Table 1). While primary cell cul- ture and in vitro co-culture consist of only a ...
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Role of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cgmp) in oxidative metabolism, inflammation and cell death: case amphotericin b
... of cAMP and cGMP in nephrotoxicity caused by AmB from the assessment of cytokines, stress oxidative, nitric oxide production and cell death in MDCK cells ...plus cAMP. Results with TNF-α showed that ...
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Cluster of differentiation 8 and programmed cell death ligand 1 expression in triple negative breast cancer combined with autosomal dominant polycystic kidney disease and tuberous sclerosis complex: a case report
... monotherapy was shown to have a manageable safety profile and durable antitumor activity therapy for pa- tients with PD-L1-positive metastatic TNBC [14]. Merck announced the phase 3 KEYNOTE-119 trial on Keytruda® ...
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