3-CHLORO-3-METHYL-2
Crystal structures of three 3 chloro 3 methyl 2,6 diarylpiperidin 4 ones
... The piperidine ring is a ubiquitous structural feature of many alkaloid natural products and drug candidates: Watson et al. (2000) asserted that during a recent 10-year period there were thousands of piperidine compounds ...
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Methyl 2 (5 chloro 1 methyl 2 oxo 2,3 dihydro 1H indol 3 ylidene)acetate
... C1 0.0283 (6) 0.0363 (7) 0.0319 (6) −0.0017 (5) 0.0015 (5) 0.0008 (4) C2 0.0347 (7) 0.0386 (7) 0.0406 (6) 0.0058 (6) 0.0016 (5) 0.0059 (5) C3 0.0409 (7) 0.0302 (6) 0.0437 (7) 0.0054 (5) 0.0065 (6) 0.0047 (5) C4 0.0331 ...
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Trace Level Quantification of Genotoxic Impurity “3 Chloro N (2 ((2 Dimethylamino) Ethyl) (Methyl) Amino) 4 Methoxy 5 ((4 (1 Methyl 1h Indol 3 Yl) Pyrimidin 2 Yl) Amino) Phenyl) Propanamide” in Osimertinib Mesylate by UPLC QDa
... impurity 3-Chloro-N-(2-((2- dimethylamino) ethyl) (methyl) amino)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl) pyrimidin-2-yl) amino) phenyl) propanamide (chloro ...
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3 Chloro 3 (9 ethyl 6 methyl 9H carbazol 3 yl)propenal
... The carbazole skeleton in (I) (Fig. 1) is planar to within ±0.020 (2) Å. The 3-chloropropenal substituent is coplanar with the carbazole ring system, with atoms Cl1, O1, C13, C14 and C15 deviating from the ...
10
2 Chloro 3 (3 dimethylaminopropylamino) 1,4 naphthoquinone
... parameters ratio is low (ca 4). In the previous structures, the number of observed data was suf®ciently high to generate data/parameters ratios well above 6. All H atoms were included in the re®nement at calculated ...
8
1 Chloro 2 methyl 3 nitrobenzene
... For information on industrial chemicals, see: Chloronitro- toluenes (2010). For the use of the title compound as a starting material in the synthesis of 7-chlorovasicine (pyrrolo[2,1-b]- quinazolin-3-ol, ...
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(3RS,4SR) Methyl 4 (2 chloro 5,8 dimethoxyquinolin 3 yl) 1 phenylpyrrolidine 3 carboxylate
... C11 0.088 (2) 0.0378 (12) 0.106 (2) −0.0050 (13) 0.0492 (18) −0.0099 (13) C12 0.0718 (18) 0.0793 (18) 0.0783 (19) 0.0021 (14) 0.0476 (16) 0.0170 (15) C13 0.0581 (14) 0.0469 (12) 0.0550 (14) −0.0054 (10) ...
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(2E) 3 (2 Chloro 8 methylquinolin 3 yl) 1 (2 methyl 4 phenylquinolin 3 yl)prop 2 en 1 one
... A mixture of 3-acetyl-2-methyl-4-phenylquinoline (260 mg, 0.001 M), 2-chloro-8-methylquinoline-3-carbaldehyde (200 mg, 0.001 M) and KOH (0.2 g) in methanol (20 ml) was stirred ...
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(E) 4 Chloro N [(E) 2 methyl 3 phenylallylidene]aniline
... N1 0.0204 (7) 0.0212 (6) 0.0190 (6) 0.0000 (5) 0.0007 (5) 0.0002 (5) C1 0.0174 (7) 0.0186 (6) 0.0189 (7) 0.0011 (6) 0.0001 (6) −0.0018 (6) C2 0.0162 (7) 0.0171 (6) 0.0182 (7) 0.0014 (6) −0.0009 (5) −0.0021 (6) C3 0.0278 ...
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5 Chloro N′ cyclohexylidene 3 methyl 1H indole 2 carbohydrazide
... C11 0.0635 (15) 0.0719 (18) 0.0463 (15) 0.0060 (14) 0.0073 (13) 0.0177 (13) C12 0.0652 (17) 0.143 (3) 0.0556 (18) −0.0114 (19) 0.0048 (14) 0.0348 (19) C13 0.112 (3) 0.122 (3) 0.065 (2) −0.040 ...
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7 Chloro 2 methyl 3 methylamino 2H 1,2,4 benzothiadiazine 1,1 dioxide
... A solution of 7-chloro-2-methyl-3-methylsulfanyl-2H-1,2,4-benzothiadiazine 1,1-dioxide [obtained as described in Di Bella et al. (1973)] (0.6 g) in a 33% w/v solution of methylamine in ...
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(2E) 3 (6 Chloro 2 methoxyquinolin 3 yl) 1 (2 methyl 4 phenylquinolin 3 yl)prop 2 en 1 one acetone monosolvate
... Data collection: CrysAlis PRO (Agilent, 2013); cell refinement: CrysAlis PRO; data reduction: CrysAlis PRO; program(s) used to solve structure: SHELXS97 (Sheldrick, 2008); program(s) used to refine structure: SHELXL97 ...
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3 Chloro 1 methyl 4 [2 (3 phenylallylidene)hydrazinylidene] 3,4 dihydro 1H 2λ6,1 benzothiazine 2,2 dione
... The dihedral angle between the C1–C6 and C13–C18 aromatic rings is 4.81 (2)° and the C9=N2—N3=C10 torsion angle is -178.1 (4)°. The linking alkyl chain takes on an extended conformation [N3—C10—C11—C12 = 179.2 ...
7
(2E) 1 (6 Chloro 2 methyl 4 phenylquinolin 3 yl) 3 (4 chlorophenyl)prop 2 en 1 one
... C19 0.0473 (10) 0.0616 (12) 0.0645 (12) −0.0061 (9) −0.0003 (9) −0.0182 (10) C20 0.0565 (11) 0.0612 (12) 0.0596 (12) −0.0132 (9) −0.0025 (9) −0.0176 (10) C21 0.0698 (13) 0.0630 (13) 0.0652 (13) −0.0134 (10) 0.0016 (10) ...
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Synthesis, Characterization and antimicrobial evaluation of New Chalcone Derivatives From3- benzyloxy-4-methoxybenzaldehyde
... with 2-Chloro substitution, compound 2c with 4- methoxy substitution and 2d with 4-Methyl, exhibited excellent antibacterial activity against the gram positive and gram negative bacterial ...
8
2 Chloro 1 (3 mesityl 3 methylcyclobutyl)ethanone
... Cl1A—C16A—C15A 113.5 (8) Cl1B—C16B—C15B 113.8 (13) H atoms were positioned geometrically and treated using a riding model, fixing the bond lengths at 0.93, 0.96, 0.97 and 0.98 A ˚ for aromatic, methyl, methylene ...
10
3 Chloro 2 methylanilinium dihydrogenphosphate
... P1 0.0413 (4) 0.0243 (3) 0.0221 (3) −0.0007 (2) 0.0007 (2) −0.00082 (18) O1 0.0444 (9) 0.0731 (13) 0.0312 (9) 0.0113 (9) 0.0005 (7) −0.0125 (8) O2 0.0800 (12) 0.0248 (8) 0.0297 (8) −0.0045 (8) ...
8
Lai-Hao Wang*, Fong-Ge Fang, Wan-Jung Tu
... as 3-isothiazolones) in such biocidal products is well established, since this class of compound includes highly active biocidal compounds (Baum R et ...and 2-methyl-4- isothiazolin-3-one ...
6
5 Chloro 3 ethylsulfinyl 7 methyl 2 (4 methylphenyl) 1 benzofuran
... 3-Chloroperoxybenzoic acid (77%, 224 mg, 1.0 mmol) was added in small portions to the stirred solution of 5-chloro-3- ethylsulfanyl-7-methyl-2-(4-methylphenyl)-1-benzofuran (285 mg, 0.9 ...
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(2E) 3 (2 Chloro 7 methylquinolin 3 yl) 1 (6 chloro 2 methyl 4 phenylquinolin 3 yl)prop 2 en 1 one ethanol monosolvate
... C28 0.0208 (8) 0.0256 (9) 0.0175 (8) −0.0051 (7) 0.0016 (7) −0.0041 (7) C29 0.0395 (12) 0.0253 (10) 0.0417 (12) −0.0113 (9) −0.0012 (9) −0.0120 (9) O2 0.053 (2) 0.061 (2) 0.064 (3) −0.009 (2) ...
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