48/80, Compound 48/80
Original Article Bee venom ameliorates compound 48/80-induced atopic dermatitis-related symptoms
... Compound 48/80 and Evans blue were pur- chased from Sigma Chemical Co. (St. Louis, MO, USA). Colonies of natural honeybees (Apis mellifera L.) used in this study were maintained at the National ...
8
The Mast Cell Degranulator Compound 48/80 Directly Activates Neurons
... to compound 48/80 was also different between these 3 neuronal ...3. Compound 48/80 (c48/80) evoked spike discharge in primary cultured enteric ...
9
Inhibitory effect of a new orally active cedrol-loaded nanostructured lipid carrier on compound 48/80-induced mast cell degranulation and anaphylactic shock in mice
... bation of mast cells with compound 48/80 in the positive control group showed significant increase of histamine release compared to the normal control group. In contrast, preincubation of mast cells ...
20
Mast cell stabilizing effect of hydroalcoholic extract of Jasminum sambac leaves against compound 48/80-induced degranulation
... The chemicals used in this study were purchased from different suppliers. Ferric chloride, sodium hydroxide, sodium chloride, glucose, sodium bicarbonate, potassium chloride, sodium dihydrogen phosphate, gelatin, ...
8
Influence of Ketotifen, Cromolyn Sodium, and Compound 48/80 on the survival rates after intestinal ischemia reperfusion injury in rats
... mediators. Compound 48/80 is a condensation prod- uct of p-metoxyphenethyl-methylamine and formaldehyde, and is a potent inducer of mast cell de- granulation in rats ...
11
Curcumin Inhibits Compound 48/80 Induced Systemic Anaphylaxis
... Mast cells are bone marrow-derived effector cells of the immune system, found abundantly in connective tissue, skin, mucosal membranes, and tissues which interface with the external environment. Mast cells are the ...
6
Original Article Inhibition of itch-related responses by selectively ablated serotonergic signals at the rostral ventromedial medulla in mice
... of compound 48/80 resulted in a dramatic increase in itch behavior between naive group and saline group; (2) 5,7-DHT- treated mice showed profound scratching defi- cits after intradermal injection of ...
5
Inhibition of release of inflammatory mediators in primary and cultured cells by a Chinese herbal medicine formula for allergic rhinitis
... that RCM-101, a herbal formula with 18 constituent Chi- nese herbs, has activity directed to inhibition of the syn- thesis or release of multiple key inflammatory mediators. Mast cell-derived mediators, particularly ...
8
Fasting mitigates immediate hypersensitivity: a pivotal role of endogenous D-beta-hydroxybutyrate
... It has been reported that, the restriction of nutrition supplementation creates various enhancing effect on the cell mediated defense. To exclude the possible defense response by food deprivation other than increased D- ...
10
Effects of relaxin on mast cells In vitro and in vivo studies in rats and guinea pigs
... The results of the current study demonstrate that relaxin inhibits histamine release by mast cells. This effect is related to the peptide concentrations, and could be observed in both isolated rat serosal mast cells ...
8
Antipruritic effect of cold stimulation at the Quchi Acupoint (LI11) in Mice
... Although acupuncture or moxibustion has been prac- ticed for over 2,500 years, the cooling device was in- vented only in recent 200 years and was unavailable for the traditional medical treatment. Thus, there were no ...
8
Evaluation of Effect of Taxus baccata Leaves Extract on Bronchoconstriction and Bronchial Hyperreactivity in Experimental Animals
... The present investigation was undertaken to evaluate the bronchodilating effect and bronchial hyperreactivity of alcoholic extract of Taxus baccata Linn. (AET) leaves in experimental animals. Bronchodilator activity of ...
7
n heterocyclic 4 piperidinamines pdf
... The in vivo antihistamine activity was evaluated by the compound 48/80 induced lethality test in rats and the antihistamine-induced lethality test in guinea pigs after oral and/or subcut[r] ...
10
ANTIALLERGIC, ANTIANAPHYLACTIC & MAST CELL STABILIZING POTENTIAL OF VITIS VINIFERA IN MANAGEMENT OF ASTHMA
... Rats were divided into five groups (n=5). On the 1 st day of sensitization, all the animals from each group were injected with Compound 48/80 (1mg/kg, s.c.). Animals belonging to group I was ...
12
Mast cell chymase potentiates histamine induced wheal formation in the skin of ragweed allergic dogs
... degranulation. To test the hypothesis that chymase modulates histamine-induced plasma extravasation, we measured wheal formation following intradermal injection of purified mast cell chymase and histamine into the skin ...
6
Sex Differences in Scratching Behaviors Induced by Intradermal Injections of Pruritogenic Chemicals in C57BL/6 Mice
... pruritogenic compound 48/80 and histamine-indepen- dent pruritogenic ...pruritogenic compound 48/80 and histamine-independent pruritogenic ...pruritogenic compound ...
7
TO INVESTIGATE THE MAST CELL STABILIZATION AND ANTIANAPHYLACTIC ACTIVITY OF ETHANOLIC EXTRACT OF THESPESIA POPULNEA BARK.
... compound 48/80, which is a mast cell degranulator and has been used as a direct and convenient reagent to study the mechanism of anaphylaxis [3] ...
9
Short-term tocolytics for preterm delivery – current perspectives
... neonatal morbidity were not reduced in these populations. A recent systematic review and network meta-analysis of 95 randomized controlled trials investigating tocolytic therapy concluded that the probability of delivery ...
7
Mesospheric CO above Troll station, Antarctica observed by a ground based microwave radiometer
... Rothman et al. (2005). The a priori temperature and CO profiles are constructed from NCAR’s Whole Atmosphere Community Climate Model with Specified Dynamics (SD- WACCM) data (Lamarque et al., 2012) (description in Sect. ...
10
Risk factors and prognosis of pain events during mechanical ventilation: a retrospective study
... The highest BPS within 48 h after initiation of mechan- ical ventilation was recorded. Data collected included age, gender, body weight, height, surgery (cardiac or non-cardiac), and the acute physiology and ...
7