5-fluorouracil
Efficacy of dermabrasion along with topical 1% 5-fluorouracil in 25 patients of vitiligo
... with 5 fluorouracil can be used as a simple office procedure, in repigmenting focal and to a lesser extent generalized stable vitiligo, which is very economical & brings early repigmentation without any ...
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RGS17 inhibits tumorigenesis and improves 5-fluorouracil sensitivity in nasopharyngeal carcinoma
... into a six-well plate. After attachment overnight, 2.5 mg/L 5-fluorouracil (5-FU) was added at the concentrations indi- cated, and the cells were incubated for 24 hours. All cells, including the ...
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Optimized synthesis of glycyrrhetinic acid-modified chitosan 5-fluorouracil nanoparticles and their characteristics
... and 5-FU and conjugating 5-FU onto the GA-CTS ...=5:1, 5-FU:CTS weight ratio =1:1, TPP concentration ...the 5-FU group, but the maximum concentration (C max ) was ...
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Degradation of the chemotherapy drug 5 fluorouracil on medical grade silver surfaces
... that 5-Fu readily degrades on a range on metal sur- faces, even when a realistic degree of surface contamination is ...of 5-Fu appear to be different on monocrystalline and polycrystalline substrates, but ...
12
Cardiotoxicity of 5-fluorouracil and capecitabine in Chinese patients: a prospective study
... drug 5-fluorouracil (5-FU) and its oral prodrug capecitabine have been reported to induce adverse cardiac effects, despite being considered as tol- erable in most cases ...[2–4]. 5-FU and ...
7
Self-assembling peptide nanofibers containing phenylalanine for the controlled release of 5-fluorouracil
... drug 5-fluorouracil (5-FU) at basic pH. As 5-FU contains the aromatic pyrimidine ring, RADA-F6 system is suitable for entrapping an aromatic drug due to effective π–π stacking with ...
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Effects of plasma concentrations of 5-fluorouracil on long-term survival after treatment with a definitive 5-fluorouracil/cisplatin-based chemoradiotherapy in Japanese patients with esophageal squamous cell carcinoma
... Originally, 5-FU was administered alone as a bolus, but more recently, it is being administered with biomodulating agents and/or through continuous infusion ...to 5-FU improves its cytotoxic activity and ...
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Methacrylic-based nanogels for the pH-sensitive delivery of 5-Fluorouracil in the colon
... calorimetry. 5-Fluorouracil (5-FU) was entrapped within methacrylic-based copolymers by a solvent evaporation ...of 5-FU and its pH ...containing 5-FU exhibited considerable ...
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Investigation of the Electrochemical Interaction Behavior of DNA with 5-Fluorouracil Derivatives
... [13]. 5-Fluorouracil (5-FU) has been increasingly employed alone or in therapy combined with various cytotoxic drugs and hormones in the treatment of several tumors, such as breast, colorectal and ...
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Hemostatic absorbable gelatin sponge loaded with 5-fluorouracil for treatment of tumors
... Results: 5-FU-HAGS (hemostatic absorbable gelatin sponge loaded with 5-fluorouracil) was successfully produced with controlled release of the content and was reproducibly suitable for local tumor ...
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Dermabration followed by topical 5% 5-fluorouracil and autologous melanocyte transplantation in stable vitiligo
... The selected lesion was anesthetized with local application of eutectic mixture of local anesthetics (EMLA) patch sixty minutes preoperatively. Electrical or mechanical dermabrader of appropriate size was used to abrade ...
5
5 Fluorouracil encapsulated silver nanoparticle for effective anticancer drug delivery
... 2013). 5-Fluorouracil is widely used in the treatment of cancer and effective against solid tumors, mainly has a better therapeutic effect on et ...However, 5-Fu has heavy toxic side effects, little ...
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A Hypothesis Concerning the Effect of Schedule on the Pattern of 5 Fluorouracil Toxicity
... as 5-fluorouracil where active enzymatic processes control both drug influx and disposition, and are known to exist in almost all cell types, including hematopoietic tissue, cardiac myocytes, and cells of ...
6
Bioavailability Study of Oral 5-Fluorouracil in Colorectal Cancer Patients.
... of 5-Fluorouracil (5-FU) when given with skimmed milk in colorectal cancer ...Oral 5-FU (500 mg/m 2 ) was administered with skimmed milk (250 ml) to colorectal cancer ...administration. ...
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Mechanism of 5 Fluorouracil Induced Apoptosis on Cultured Corneal Endothelial Cells
... surgery, 5-FU was introduced as an ad- junct agent administered by repeated subconjunctival injections after trabeculectomy to inhibit the proliferation of fibroblasts [4] ...of 5-FU up to a total dose of ...
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DEVELOPMENT AND IN VITRO EVALUATION OF 5 FLUOROURACIL NANOPARTICLES BY SALTING OUT TECHNIQUE
... Pancreatic cancer is the ninth more prevalent and challenging to treat. Several formulations are now available for the treatment of pancreatic cancer and 5-fluorouracil (5-FU) is one of the most ...
6
ENTERIC COATED 5-FLUOROURACIL CAPSULES DESIGNED TO ACHIEVE INTESTINAL TARGETING
... drug 5- Fluorouracil was used. 5-Fluorouracil (5-FU) is one of the oldest anticancer drugs and is still used in the treatment of colorectal ...cancer. 5- Fluorouracil is ...
9
Preparation of 5-fluorouracil nanoparticles by supercritical antisolvents for pulmonary delivery
... of 5-fluorouracil (5-FU) ...of 5-FU in order to deliver it directly to the respiratory ...of 5-FU precipitated from methanol-dichloromethane 50:50 had a mean particle size of 248 ...six ...
8
Controlled release of 5-fluorouracil and progesterone from magnetic nanoaggregates
... The dependence of the drug release kinetics on the par- ticle diameter can be directly correlated to the variation on the drug loading. Figure S2 (Supplementary material) focuses on the effect of the average particle ...
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TSPAN9 suppresses the chemosensitivity of gastric cancer to 5-fluorouracil by promoting autophagy
... with 5% nonfat milk (w/v) in phosphate-buffered saline (PBS) for 1 h to inhibit nonspecific binding, they were incubated with primary antibodies at room temperature for 2 ...their 5-fluorouracil ...
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