5-HT, serotonin
Serotonin signaling through the 5-HT 1B receptor and NADPH oxidase 1 in pulmonary arterial hypertension
... the 5-HT 1B receptor, and NADPH oxidase 1 ...in serotonin transporter overexpressing female mice, a model of pulmonary ...that serotonin increased oxidized protein tyrosine phosphatases and ...
10
Role of prucalopride, a serotonin (5-HT<sub>4</sub>) receptor agonist, for the treatment of chronic constipation
... nonselective 5-hydroxytryptamine receptor 4 (5-HT 4 ) agonists have been associated with significant interactions with other receptors (5-HT 1B , 5-HT 1D , and ...
8
5-HT receptors mediate lineage-dependent effects of serotonin on adult neurogenesis in Procambarus clarkii
... the serotonin receptor protein at the sites where we observe the most intense immunocytochem- ical ...of serotonin receptor proteins in crayfish neu- rons, but the relatively stable lifespan (half-life ...
22
Crystal structure of the human 5 HT<inf>1B</inf>serotonin receptor bound to an inverse agonist
... agonist-bound serotonin receptor structures, the inverse agonist-bound 5- HT 1B R structure identi fi es a basis for the ligand-mediated switch of 5-HT 1B R activity and provides a ...
13
Understanding the nature of psychiatric comorbidity in migraine: a systematic review focused on interactions and treatment implications
... 5-HT: Serotonin; 5-HTTLPR: Serotonin-transporter-linked polymorphic region; BD: Bipolar disorder; CBCL: Child Behavior Checklist; CBT: Cognitive- behavioral therapy; CGRP: Calcitonin ...
17
A comparison of duloxetine hydrochloride with fluoxetine hydrochloride in major depressive disorders: a pilot study
... of 5-hydroxy serotonin (5-HT) and nore- pinephrine (NE), versus fluoxetine, a reuptake inhibitor of 5-HT during follow up period of 16 weeks in major depressive disorder (MDD) a ...
5
Enhanced haemolymph circulation by insect ventral nerve cord: hormonal control by Pseudaletia unipuncta allatotropin and serotonin
... The ventral diaphragm (VD) in many insects is a muscular membrane that essentially partitions a perineural sinus from the rest of the abdomen. In the true armyworm moth Pseudaletia unipuncta (Lepidoptera: Noctuidae) we ...
9
Association between serotonin transporter polymorphisms (5-HTTLPR) and the MADRS Dysphoria, Retardation, and Vegetative Subscale scores in the treatment of depression
... The limitations of this study include a small sample size and lack of control group. Further studies with a larger number of subjects are needed to confirm the results of this study. Although both antidepressants adopted ...
7
Live fate mapping of joint associated fibroblasts visualizes expansion of cell contributions during zebrafish fin regeneration
... with serotonin staining. (D) Weak tph1b:mCherry expression, and no serotonin expression, in medial ...for serotonin (5-HT, green), proliferating cells (PCNA, red) and nuclei (DAPI, ...
7
Measurement of Tryptophan Metabolites in Healthy Old Men and Patients of Type 2 Diabetes Mellitus (T2DM)
... L-5-Hydroxytryptophan(5-HTP), Serotonin (5-HT), Kynu- renine (KYN), 5-hydroxy-tryptophol, Tryptophol, 5-Hydroxyindoleacetic acid (5-HIAA), Indole-3-acetic acid, ...
15
Differential role of dose and environment in initiating and intensifying neurotoxicity caused by MDMA in rats
... a serotonin (5-hydroxytryptamine; 5-HT) releaser that increases extracellular 5-HT in the brain immediately after administration ...Excessive 5- HT levels are, to ...
13
Serotonin 5-Ht6 Receptor: A Potential Target For Cognition
... The past few years have seen major advances in cognitive research, leading to an increased understanding of its pathophysiology. New targets have been identified for essential disease pathways, playing role in some ...
12
TIME COURSE OF CHANGES IN BRAIN SEROTONERGIC ACTIVITY AND BRAIN TRYPTOPHAN LEVELS IN DOMINANT AND SUBORDINATE JUVENILE ARCTIC CHARR
... of serotonin (5-HT), 5-hydroxyindoleacetic acid (5-HIAA) and tryptophan (TRP, the amino acid precursor of 5-HT) were measured, and 5-HIAA/5-HT ratios ...
15
A review of the pharmacoeconomics of eletriptan for the acute treatment of migraine
... are potent selective serotonin 5-HT 1B/1D receptor agonists. Although, the mechanism of action of triptans has not yet been established, they are hypothesized to work by various mechanisms, including ...
10
THE MONOSYNAPTIC CONNECTIONS BETWEEN THE SEROTONIN CONTAINING LP3 AND RPaS NEURONES IN HELIX ARE SEROTONERGIC
... Furthermore, the excitatory effect of locally applied 5-HT and the synaptic responses evoked by presynaptic stimulation could be similarly blocked by bath application of serotonin antago[r] ...
14
Daily variations in crustacean hyperglycaemic hormone and serotonin immunoreactivity during the development of crayfish
... that serotonin (5-hydroxytryptamine; 5-HT) is a circadian modulator of the visual system of invertebrates (Nadakavukaren et ...between 5-HT, light and some neurohormones, such as ...
9
ACUTE INTOXICATIONS WITH NEUROLEPTICS AND ANTIDEPRESSANTS
... of serotonin syndrome and rhabdomyolysis. [19, 20] Serotonin syndrome occurs most often with the use of drugs, which increase the synaptic levels of serotonin and as a consequence activation of ...
8
Effect of the probiotic Lactobacillus plantarum IS-10506 on BDNF and 5HT stimulation: role of intestinal microbiota on the gut-brain axis
... Data from mice and humans have shown that gut microbiota influence the gut–brain axis; disruption of gut microbiota communities alters the expression of the neuromodulator brain-derived neurotroph- ic factor (BDNF), the ...
6
Sleep, Serotonin, and Suicide
... Because 5-HT innervation to the PFC arises predomi- nantly from the brainstem dorsal raphe nucleus (DRN), interest has been directed toward the DRN of suicide ...more 5-HT1A binding in depressed ...
8
Personalized medicine in psychiatry: problems and promises
... 5-HT: 5-hydroxytryptophan (serotonin); 5-HTTLPR: 5-HT transporter-linked polymorphic region; ACC: anterior cingulate cortex; ANK3: ankyrin 3; APOE: apolipoprotein E; ...
35