α-1,3-Glucosidase
SYNTHESIS AND BIOLOGICAL ACTIVITY OF SOME NOVEL IMIDAZOLIDINE ANALOGUES AS POTENT ANTIDIABETIC AGENT
... the 1 position, one at the 3 position and two at the 5 position in their ring structure respectively and thus exhibiting potent as well as wide range of pharmacological ...by α-amylase, ...
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Intestinal α glucosidase and some pancreatic enzymes inhibitory effect of hydroalcholic extract of Moringa stenopetala leaves
... adults being affected and 5.1 million people killed in the year 2013. The prevalence is expected to be 592 million in the year 2035, with the greatest increases expected in low- and middle-income developing countries of ...
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α Glucosidase and β glucosidase from psychrotrophic strain arthrobacter sp C2 2
... A, 3 ml (0–20%) buffer B, 12 ml (20–38%) buffer B, 10 ml (38%) buffer B, 15 ml (38–60%) buffer B, 3 ml (60–100%) buffer B, and 5 ml (100%) buffer B at a flow rate of ...containing glucosidase ...
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Polyphenol Profile, Antioxidant and Hypoglycemic Activity of Acalypha hispida Leaf Extract
... of the extract. The hypoglycemic effect was shown after the administration of an extract followed by sucrose. Both the groups given 300 mg/kg of extract and the group given 4.5 mg/kg acarbose exhibited significantly ...
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PHYTOCHEMICAL SCREENING AND IN VITRO Α -AMYLASE AND Α-GLUCOSIDASE INHIBITORY POTENTIAL OF CLERODENDRUM VOLUBILE LEAF EXTRACT
... In this study, the inhibitory effect of methanolic C. volubile extract on these key enzymes linked with diabetes in vitro was justified. The phytochemical screenings (Tables 1 and 2) revealed the presence of ...
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α-Glucosidase inhibitors from the bark of Mangifera mekongensis
... such as microvascular (i.e., retinal, renal, and possibly neu- ropathic), macrovascular (i.e., coronary and peripheral vascular), and neuropathic (i.e., autonomic and peripheral) complications [3, 4]. Previously, ...
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An In Vitro Study on the inhibitory Activities of Eugenia jambolana Seeds Against Carbohydrate Hydrolyzing Enzymes
... pancreatic α-amylase, rat intestinal α-glucosidase, and sucrase, have been studied using in vitro model ...0.01) α-amylase, α-glucosidase, and sucrase activities in a dose- ...
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Inhibitory Effects of Swietenia Mahagoni Seeds Extract on Α-Glucosidase and Α-amylase
... as α-glucosidase and α-amylase ...process, α-glucosidase act as vital enzyme in catalyzing the disaccharides and oligosaccharides into glucose ...Meanwhile, α-amylase imply in ...
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Screening of In Vitro Antidiabetic Activity of Herbal Formulation Meshashringi
... The α-glucosidase inhibitory activity was determined by measuring the release of 4-nitrophenol from p-nitrophenyl α-D ...p-nitrophenyl α-D-glucopyranoside, ...
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Preparation and characterization of PLGA loaded nanoparticles obtained from D. melanoxylon Roxb. leaves for their antiproliferative and antidiabetic activity
... Introduction: Diospyros melanoxylon Roxb. is traditionally used medicinal plant. Previously, we confirmed the better antiproliferative and antidiabetic activity of ethyl acetate fractions (EAF) obtained from D. ...
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Purification and characterization of α-glucosidase from Penicillium chrysogenum.
... α-glucosidase (EC: 3.2.1.20) was isolated and purified from Penicillium chrysogenum Thom ATCC 10106 by ammonium sulphate precipitation (75%), DEAE-cellulose and Sephadex G-200. The specific activity was 140 ...
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Target guided isolation, in vitro antidiabetic, antioxidant activity and molecular docking studies of some flavonoids from Albizzia Lebbeck Benth bark
... The 3D coordinates of crystal structure of B. cereus oligo- 1,6—glucosidase (PDB ID: 1UOK) was downloaded from the RCSB protein data bank (http://www.rcsb.org/pdb) set up at Brookhaven National Laboratory in 1971. ...
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EVALUATION OF α AMYLASE AND α GLUCOSIDASE ENZYME INHIBITORY ACTIVITIES OF TRICHURIELLA MONSONIAE BENNET
... containing α-amylase solution ...of 1% starch solution in ...of 3, 5 di-nitro salicylic acid to 3- amino-5- nitro salicylic acid and the absorbance was measured at 540 nm (ELICO SL159 ...
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Assessment of Mechanism of Action of Antidiabetic Activity of Calocybe indica by Enzyme Inhibitory Activity
... by α αα α α-glucosidase The α-glucosidase inhibitory activity was determined by measuring the release of 4- nitrophenol from p-nitrophenyl α-D ...nitrophenyl ...
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Soil hydrolase activities and kinetic properties as affected by wheat cropping systems of Northeastern China
... is 1/3 of that in Liaoning province, which has been one of the higher crop production provinces in ...(β-galactosidase, α-galactosidase, β-glucosidase, α-glucosidase, urease, ...
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In vitro anti-diabetic activity of flavonoids and pheophytins from Allophylus cominia Sw . on PTP1B, DPPIV, alpha-glucosidase and alpha-amylase enzymes
... The flavonoid rich fractions from A. cominia inhibited DPPIV enzyme (75.3±2.33%) at 30 µg/ml and produced a concentration-dependent inhibition against DPPIV with a Ki value of 2.6 µg/ml. At 30 µg/ml, flavonoids and ...
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Oligosaccharide synthesis using a glucosidases of different origin
... (USA). α-Glucosidase from Aspergillus awamori was a kind gift by ...intestinal α-glu- cosidase (saccharase-isomaltase complex) was prepared as described by Kolínska (K OLÍNSKÁ & S EMENZA ...The ...
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Alpha-glucosidases from Non-hematophagous Organisms Crystallize Heme in Vitro
... Abstract: Hemozoin (Hz), a heme crystal first known as a malaria pigment, reduces heme toxicity to hematophagous organisms such as protozoans, worms, and insects. The mechanism of Hz synthesis remains poorly understood, ...
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1 Phenolic Constituents with Antioxidant and
... 1 17.74 ± 0.64 283.99 ± 2.61 20 11.50 ± 0.67 370.90 ± 18.16 2 18.21 ± 0.84 275.68 ± 2.93 21 10.43 ± 0.41 584.03 ± 26.87 3 76.38 ± 7.28 298.21 ± 5.68 22 7.99 ± 0.52 6.32 ± 0.96 4 35.04 ± 1.91 190.03 ± 9.30 ...
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Journal of Applied Pharmaceutical Science
... Obesity and the onset of diabetes are two closely liked medical complications prevalent globally. Postprandial hyperglycemia is one of the earliest abnormalities of glucose homeostasis associated with type 2 diabetes. ...
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