A contingency gene has a low mutation rate
A Low Mutation Rate For Chloroplast Microsatellites
... growth has been fairly uniform. of cpSSR variation is needed before it can be deter- mined whether cpSSRs may have value in plant phylo- Because the mutation rate at SSR loci is much higher than ...
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The “fossilized” mitochondrial genome of Liriodendron tulipifera: ancestral gene content and order, ancestral editing sites, and extraordinarily low mutation rate
... conica, rate estimates were taken from previously pub- lished reports [2,48] and incorporated into our analysis using an estimate of 6 mya at the base of the Silene ...concatenated gene alignments for ...
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Low phospholipid associated cholelithiasis: association with mutation in the MDR3/ABCB4 gene
... Thr175Ala mutation was identified originated from Northern Europe, so they may have inherited a founder mutation from a shared ...This mutation has also been recently identified in adults with ...
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The Mutation Rate and Cancer
... in gene inactivation, usually by trunca- region of BAX ( Rampino et ...these gene products, thereby enhancing the progression of the cancer ...It has been proposed that tor II inhibits growth of ...
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Low Impact of Germline Transposition on the Rate of Mildly Deleterious Mutation in Caenorhabditis elegans
... per-generation rate of transposon accumu- lation: The TD procedure was applied at generations 0 and 40 using separate single-worm descent lines, composing a ran- dom subset of the lines used for fitness ...the ...
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Critical mutation rate has an exponential dependence on population size for eukaryotic-length genomes with crossover
... model has been developed to begin to incorporate features to allow it to be applied to prokaryotic as well as eukar- yotic species through the introduction of lateral gene transfer 31 ; the transfer of ...
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An Unusually Low Microsatellite Mutation Rate in Dictyostelium discoideum, an Organism With Unusually Abundant Microsatellites
... high mutation rate for microsatellites, lead- ing to a higher rate of neutral evolution at these ...discoideum has an unusually low microsatellite mutation rate, ...
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Low Frequency of 185delAG Founder Mutation of BRCA1 Gene in Iranian Breast Cancer Patients
... study has provided the preliminary information to understand the level of involvement of BRCA1 and BRCA2 mutations in the breast cancer occurrence of Iranian ...BRCA1 gene is ongoing to confirm the ...
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Familial Hypercholesterolemia in an Azorean Family: A Novel Mutation in the Low Density Lipoprotein Receptor Gene
... The genetic study of relatives of affected individuals is undoubtedly the most cost-effective method of de- tecting new cases of FH and several countries have already begun cascade screening programs [14]-[18]. Fur- ...
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Specific mutation screening of <em>TP53</em> gene by low-density DNA microarray
... The low-density DNA microarray used in the present study is a variant of the conventional microarray format employing tandem hybridization, used to detect some point mutations in DNA ...TP53 gene. 14 The ...
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Low Rate of
... It has been mentioned that ...babA2 gene was more related to duodenal ulcers and gastric cancer [5,22], which is not in agreement with our ...association has been observed between the presence of ...
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Selection for Chaperone-Like Mediated Genetic Robustness at Low Mutation Rate: Impact of Drift, Epistasis and Complexity
... small mutation rate, we have shown that contrary to what is commonly assumed, the selection for genetic robustness does not require high mutation ...what has been suggested before (G ardner ...
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Estimate of the Spontaneous Mutation Rate in Chlamydomonas reinhardtii
... their rate, distribution across the genome, and fitness consequences, is of central importance to ...the low rate of mutation has made it difficult to study spontaneous mutagenesis, and ...
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Critical mutation rate has an exponential dependence on population size
... high mutation rates, individuals with greater mutational robustness can outcom- pete those with higher fitness, a concept that has been referred to as ...the mutation rate that can be ...
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Saccharomyces cerevisiae S288C Has a Mutation in FL08, a Gene Required for Filamentous Growth
... in pseudohyphal formation: A number of laboratory strains (S288C and W303) have a recessive mutation in the FL08 gene that blocks haploid invasive growth and diploid pseu[r] ...
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The saving rate in Japan: Why it has fallen and why it will remain low
... By 2005, though, fully 19.9 percent of the Japanese population was aged 65 and above, the highest proportion in the OECD. This figure is projected to increase further to 36 percent by 2050. We investigate the role of TFP ...
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The saving rate in Japan: Why it has fallen and why it will remain low
... Given values of f t and m j , we can calculate M j,t for all j and t. We have data for 2001 that allow us to estimate the number of children per adult for age intervals of parents that generally span five years. From ...
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GENETIC VARIABILITY AND RATE OF GENE SUBSTITUTION IN A FINITE POPULATION UNDER MUTATION AND FLUCTUATING SELECTION
... Compared with the case of neutral mutations, the fluctuation of selection intensity caused by temporal and spatial heterogeneity of environments gen- erally increases th[r] ...
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Adaptive Mutation: Has the Unicorn Landed?
... (1996). of a gene may depend critically on its proximity to a site where DNA synthesis is active. Thus, what is special about the episome may be simply the frequency and persistence of the nick at oriT. But ...
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Correlation Between Mutation Rate and Genome Size in Riboviruses: Mutation Rate of Bacteriophage Qβ
... any mutation in the UAG codon and 2/48 plaques showed mutations at other sites (T1431C and C1213T, both ...fore, mutation frequency does not seem to depend on whether amber mutants or revertants were ...a ...
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