A-type natriuretic peptide receptor
Evidence of a guanylyl cyclase natriuretic peptide receptor in the gills of the new zealand hagfish Eptatretus cirrhatus (Class Agnatha)
... developed natriuretic peptide ...possess natriuretic-peptide-like immunoreactivity (Reinecke et ...located natriuretic peptide binding sites in the kidney and ventral aorta of ...
10
Natriuretic peptide receptor A as a novel target for cancer
... the receptor-GC sig- naling motif ...the receptor unresponsive to ligand binding or cause constitutive activation of GC activity [21], sug- gesting that this conserved structure plays a critical role in ...
6
Pseudomonas aeruginosa Expresses a Functional Human Natriuretic Peptide Receptor Ortholog: Involvement in Biofilm Formation
... eukaryotic peptide, dynor- phin, was shown able to freely cross the membrane of ...the type I periplasmic binding fold protein family, and the Uniprot database claims that AmiC is located in the periplasmic ...
12
ANP-ing Up Diabetes: Impaired Natriuretic Peptide Action in Muscle Forms a Mechanistic Link Between Obesity and Diabetes
... natriuretic peptide receptor signaling in skeletal muscle links obesity to type 2 diabetes. Potter LR, Abbey-Hosch S, Dickey DM: Natriuretic peptides, their receptors, and cyclic guanosi[r] ...
7
Atrial and brain natriuretic peptides stimulate the production and secretion of C type natriuretic peptide from bovine aortic endothelial cells
... stimulatory effect of ANP, BNP and ANP also significantly enhanced the production of new CNP protein (translation) and mRNA expressed in the BAEC. In contrast, C-ANP-4-23, a truncated form of ANP which selectively binds ...
8
Meta-analysis of B-type natriuretic peptide in diagnosis of congestive heart failure in different clinical settings
... is structurally similar to atrial natriuretic peptide. It is mainly synthesized and secreted by both the atria and ventricles. When the wall of the ventricle is stretched in response to volume or pressure ...
12
Exenatide infusion decreases atrial natriuretic peptide levels by reducing cardiac filling pressures in type 2 diabetes patients with decompensated congestive heart failure
... were: type 1 diabetes, ongoing treatment with inotropic agents, acute coronary syndrome or documented acute myocardial infarction within the previous 8 weeks, active myocarditis, significant aortic stenosis or ...
9
SYNTHESIS OF POTENT ANTAGONISTS FOR THE NATRIURETIC PEPTIDE CLEARANCE RECEPTOR
... The natriuretic peptide (NP) family comprises four structurally related bioactive ...The natriuretic peptides ANP, BNP, and CNP demonstrate a number of actions on the cardiovascular system including: ...
5
Natriuretic peptide receptor mRNAs in the rat and human heart
... atrial natriuretic peptide (ANP), a member of the natriuretic peptide family, has direct effects on cardiac muscle ...of natriuretic peptide-binding sites in the heart have ...
7
Characterization of the atrial natriuretic factor system in lungs of the toad Bufo paracnemis
... of natriuretic peptide ...third type, the C receptor, exists as a disulfide- bridged dimers that, under reducing conditions, appears as a protein with a molecular mass of 66 ...This ...
7
Identification of a potent serum factor that causes desensitization of the receptor for C-Type natriuretic peptide
... The contents of cGMP in cultured cell lines were deter- mined as previously described. Human aortic smooth muscle cells were from Clonetics and cultured as instructed by the supplier. NIH/3T3 cells over-expressing rat ...
9
Expression of C-type Natriuretic Peptide and its Specific Guanylyl Cyclase-Coupled Receptor in Pig Ovarian Granulosa Cells
... atrial natriuretic peptide (ANP), which is a functional antagonist to angiotensin II (Ang II) in other tissues ...GC-coupled receptor and endogenous CNP synthesis, using quantitative in vitro ...
12
Synthesis, secretion, function, metabolism and application of natriuretic peptides in heart failure
... uretic peptide (NP) system includes atrial NP (ANP), B- type NP (BNP, also called brain NP), C-type NP (CNP), dendroaspis NP (DNP) and urodilatin, with three recep- tors: NP receptor-A ...
21
β Cell-specific deletion of guanylyl cyclase A, the receptor for atrial natriuretic peptide, accelerates obesity-induced glucose intolerance in mice
... B-type natriuretic peptides (BNP) moderate arterial blood pres- sure and improve energy metabolism as well as insulin sensitivity via their shared cGMP-producing guanylyl cyclase-A (GC-A) ...of type ...
14
Pressure independent cardiac hypertrophy in mice with cardiomyocyte restricted inactivation of the atrial natriuretic peptide receptor guanylyl cyclase A
... specific receptor for C-type natriuretic peptide) and NPR-C, to stimulate cardiomyocyte ...C-type natriuretic peptide (CNP) and NPR-C gene– disrupted mice found no ...
10
Biomarkers in acute myocardial infarction
... Atrial natriuretic peptide; AVP: Arginine vasopressin; BNP: B-type natriuretic peptide; CAD: Coro- nary artery disease; CTproET1: C-terminal pro-endothelin 1; CKMB: Creatine kinase MB ...
11
N-terminal pro-B-type natriuretic peptide level inversely associates with metabolic syndrome in elderly persons
... common receptor, guanylyl cyclase-A (GC-A), which leads to biological actions through a cyclic guano- sine monophosphate (cGMP)-dependent pathway and has an inhibition effect of the renin–angiotensin–aldosterone ...
7
Endogenous vascular synthesis of B type and C type natriuretic peptides in the rainbow trout
... The functional significance of vascular NPs in mammals has been extensively reviewed (Ahluwalia et al., 2004; de Bold and de Bold, 2005; Woodard and Rosado, 2008). CNP and, to a lesser extent, ANP are produced in both ...
9
Radionuclide Imaging of Neurohormonal System of the Heart
... angiotensin receptor blockers are clinically applied to regulate the neurohormonal levels, but further utili- zation guidance and dosage recommendation should be in depth investigated [5, ...
14
Persistent pulmonary hypertension of the newborn
... Atrial Natriuretic Peptide; ATP: Adenosine Triphosphate; BNP: B-type Natriuretic Peptide; BPD: Broncho Pulmonary Dysplasia; CHD: Congenital Heart Disease; CGMP: Cyclic guanosine ...
18