ABC-Transporters (ABCT)
The molecular basis of phosphite and hypophosphite recognition by ABC-transporters
... cognate ABC transporters is not well ...compound transporters 18, 19, 30, 34 ...hypophosphite ABC transporters from environmental ...these transporters allow bacteria to scavenge ...
13
Control of Plasma Membrane Permeability by ABC Transporters
... of ABC transporters in directly exporting drugs from cells but also in con- trolling the composition of membranes in which they are ...and ABC transporters in general as direct drug exporters ...
12
ATP-binding cassette (ABC) transporters in normal and pathological lung
... MRP4 (ABCC4) and MRP5 (ABCC5) genes map to 13q32.1 and 3q27.1 respectively. MRP4 protein is highly expressed in the kidney and prostate and MRP4 mRNA is present in the lung [55,99]. MRP5 mRNA is ubiquitously expressed, ...
16
Evolutionary Analyses of ABC Transporters of Dictyostelium discoideum
... transmembrane transporters with related ATP- binding domains from the bacterial ...use ABC (ATP-binding cassette) transporters for both import and export, eukaryotes are thought to use them only for ...
10
Peroxisomal ABC transporters
... The isolation and characterisation of mutant alleles have provided considerable insight into the functions of peroxi- somal ABC transporters in plants. The ped3 allelic series and the pxa1-1 mutant were ...
18
ABC transporters are involved in defense against permethrin insecticide in the malaria vector Anopheles stephensi
... A total of 200 untreated larvae of An. stephensi at the third instar were pooled in 15 ml of RNAlater stabilization solu- tion (Qiagen, Hilden, Germany) and provided to an exter- nal company (GATC Biotech AG, Costance, ...
7
A Review on ATP Binding Cassette (ABC) Transporters
... including lipids, sugars, amino acids, metal ions, peptides, and proteins, and a large number of hydrophobic compounds and metabolites across extra- and intracellular membranes 1 . They have been mainly documented to ...
9
Do ABC transporters regulate plasma membrane organization?
... peroxisomal ABC transporters have no direct effects on PM organization, they greatly contribute to lipid catabolism, providing substrates for alpha- and beta- oxidation and thus participating in whole lipid ...
17
Enhanced acid-stress tolerance in Lactococcus lactis NZ9000 by overexpression of ABC transporters
... all ABC family transporters, which may share some com- mon acid-stress response ...four ABC transporters confer acid-stress tolerance to ...
14
Plant ABC transporters
... the ABC transporters: PDR5, SNQ2 and ...of ABC transporters, exhibiting a mirror topol- ogy with respect to MDR and MRP ([22^24,63^65]; ...three ABC transporters confer re- ...
26
Peroxisomal ABC transporters: functions and mechanism
... (ABC) transporters of subfamily D; (ABCD) and are activated by specific acyl CoA synthetases for further ...half transporters that homodimerize and have distinct but partially overlapping substrate ...
7
ABC transporters as multidrug resistance mechanisms and the development of chemosensitizers for their reversal
... When one of two NBDs of Pgp is inactivated, not only drug transport but also ATP hydrolysis of normal NBD is inhibited. This result indicates that two NBDs would func- tion cooperatively and they could not hydrolyze ATP ...
13
ABC and MFS Transporters: A reason for Antifungal drug resistance
... alterations. ABC proteins and MFS pumps both differing in the mechanism by which they harvest ...energy. ABC transporters are basically dependent upon the ATP phosphorylation for energy whereas MFS ...
7
Abcc6 deficiency in mice leads to altered ABC transporter gene expression in metabolic active tissues
... between ABC trans- porters of mice and man (summarized in [1]). The ABC transporters are highly variable expressed in different ...human ABC transporters have been implicated in caus- ...
7
Examining the role of ABC lipid transporters in pulmonary lipid homeostasis and inflammation
... (ABC) transporters and extracellular lipid acceptors such as high-density lipoproteins (HDL) [10, ...48 ABC transporters have been identified that facilitate the movement of a diverse range of ...
9
Development of an accumulation assay and evaluation of the effects of efflux pump inhibitors on the retention of chlorhexidine digluconate in Pseudomonas aeruginosa and Staphylococcus aureus
... inhibit ABC pumps albeit in high concentrations ...of ABC transporters in the transport of the biocide chlorhexidine digluconate was evaluated using CCCP and reserpine as efflux pump ...
9
Characterization of a potential ABC-type bacteriocin exporter protein from Treponema denticola
... bacteriocin ABC trans- porter, and bacteriocin immunity proteins are involved in bacteriocin production ...Bacteriocin ABC transporters have two functional domains: a peptidase C39 domain, which is ...
11
Modularity analysis based on predicted protein-protein interactions provides new insights into pathogenicity and cellular process of Escherichia coli O157:H7
... Module 4 consists of 53 proteins, 51 of which overlap with KEGG pathway ecs02010: ATP-binding cassette (ABC) transporters (Additional File 11, Figure S1).. ABC trans- porters play an imp[r] ...
23
Transcriptomes analysis of Aeromonas molluscorum Av27 cells exposed to tributyltin (TBT) : unravelling the effects from the molecular level to the organism
... the ABC transporters (IPR001140), involved in ion export from the cell (Chang, ...ZntB transporters (IPR002523), which mediate the transport of magne- sium and zinc, ...these transporters, ...
8
Insecticide resistance and resistance mechanisms in bed bugs, Cimex spp (Hemiptera: Cimicidae)
... [90] reported that there were kdr mutations and/or differentially expressed genes including metabolic genes P450s, esterases, ABC transporters, and cuticular protein genes associated wit[r] ...
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