Accelerated atherosclerosis
Angiotensin II–accelerated atherosclerosis and aneurysm formation is attenuated in osteopontin deficient mice
... Osteopontin (OPN) is expressed in atherosclerotic lesions, particularly in diabetic patients. To determine the role of OPN in atherogenesis, ApoE –/– OPN +/+ , ApoE –/– OPN +/– , and ApoE –/– OPN –/– mice were infused ...
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Molecular mechanisms of hydrogen sulfide against uremic accelerated atherosclerosis through cPKCβII/Akt signal pathway
... protein kinase C β II (cPKC β II)/Akt signaling pathway in the formation of atherosclerosis is still controversial. Methods: 8-week-old male ApoE −/− mice were treated with 5/6 nephrectomy and high-fat diet to ...
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Altered lipoprotein metabolism in chronic inflammatory states: proinflammatory high density lipoprotein and accelerated atherosclerosis in systemic lupus erythematosus and rheumatoid arthritis
... predict accelerated atherosclerosis, manifested as coronary artery disease (CAD) or stroke ...for atherosclerosis whereas subnormal levels of HDLs are an independent risk factor for the same disease ...
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The immunomodulatory parasitic worm product ES-62 reduces lupus-associated accelerated atherosclerosis in a mouse model.
... viteae. Accelerated atherosclerosis frequently occurs in systemic lupus erythematosus (SLE), resulting in substantial cardiovascular morbidity and ...in atherosclerosis: ES-62-based drugs may ...
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The Prebiotic Inulin Aggravates Accelerated Atherosclerosis in Hypercholesterolemic APOE*3-Leiden Mice
... As atherosclerosis is provoked by both inflammation and hyperlipidemia, we aimed to determine the effect of inulin supplementation on atherosclerosis development in hypercholesterolemic APOE*3-Leiden (E3L) ...
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Biomarkers of oxidant stress, insulin sensitivity and endothelial activation in rheumatoid arthritis: a cross sectional study of their association with accelerated atherosclerosis
... Non-diabetic patients with hyperinsulinaemia tend to be more obese and suffer more frequently from hypertension and myocardial infarction [7]. Insulin was elevated and HOMA-S decreased in our RA patients, but glucose ...
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Treatment with apolipoprotein A 1 mimetic peptide reduces lupus like manifestations in a murine lupus model of accelerated atherosclerosis
... Figure 6 Unaffected lipid profiles with modified plasma antigen levels and monocyte chemotactic activity in representative mice. Luminex- based bead array was performed for plasma chemokines and cytokines, including: (a) ...
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Molecular imaging of endothelial activation and mineralization in a mouse model of accelerated atherosclerosis
... instability and therefore the risk of subsequent deleterious clinical events (myocardial infarction, stroke). Preliminary clinical studies showed the ability of sodium fluoride ([18F]NaF) positron emission tomography ...
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Imaging VEGF receptor expression to identify accelerated atherosclerosis
... non-diabetic atherosclerosis-prone ApoE −/− mice, a model where atherosclerosis is accelerated by ...ated atherosclerosis and this conclusion is supported by immunohistochemical analyses of ...
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Vasculitis: mechanisms involved and clinical manifestations
... Systemic vasculitis is characterized by multiple phenotypes that reflect the different pathogenic mechanisms that are responsible for inducing inflammation in the large, medium and small blood vessels (arterioles, ...
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Study of Cardiac Abnormalities in HIV Patients and their Correlation with CD4 Count
... and accelerated atherosclerosis in HIV patients,the most common complications include diastolic dysfunction, left ventricular systolic dysfunction ,pericardial effusion, dilated cardiomyopathy and coronary ...
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A study of Lipoprotein [a] Estimation in stroke patients with Diabetes Mellitus
... In a recent study Lipoprotein[a] values were associated with permanent cessation of flow and occlusive arterial thrombosis (69). Analysis of damaged arterial segments showed Lipoprotein[a] incorporation in the ...
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Leg Atherosclerosis in Japanese COPD Patients: Prevalence of Undiagnosed Peripheral Artery Disease and Association between Leg Atherosclerosis and Clinical Indices
... leg atherosclerosis and clinical indices, which predict COPD mortality in Japanese COPD ...of atherosclerosis of the legs, pulmonary function, body mass index, modified Medical Research Council (MMRC) ...
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Paediatric dyslipidemia as a predictor of dyslipidemia and carotid artery thickening in young adults : findings from the Childhood Determinants of Adult Health (CDAH) Study, the Cardiovascular Risk in Young Finns Study, and the Bogalusa Heart Study
... ABBREVIATIONS AAP = American Academy of Pediatrics AHA = American Heart Association apo = apolipoprotein ARIC = Atherosclerosis Risk in Communities ARMY = Atherosclerosis Risk-Factors in[r] ...
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Serum fibroblast growth factor 21 levels are related to subclinical atherosclerosis in patients with type 2 diabetes
... Recently, more studies have indicated the relevance of FGF21 to CVD in humans. Chow et al. found that ele- vated serum FGF21 levels were associated with carotid IMT independent of cardiovascular risk factors [15]. In ...
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<p>Biomarkers of subclinical atherosclerosis in patients with psoriatic arthritis</p>
... levels of HDL2 and HDL3 were lower than those in the control group (p<0.001 and p<0.05, respectively). 71 More recently, Tam et al, in a case – control study, showed that patients with PsA had higher HDL-C levels, ...
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Original Article Efficacy of pravastatin on carotid artery atherosclerosis plaque after cerebral infarction and the change of C-reactive protein level
... As one non-antibody protein, CRP was synthe- sized in hepatocytes after being stimulated by cytokines. It is an acute response protein reflecting body inflammation, and can work as one index for atherosclerosis ...
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GPU based parallel acceleration for fast C-arm cone-beam CT reconstruction
... To acquire 3D volumetric images, several categories of algorithms are explored. One of the major category is the iterative algorithms such as ART combined with compress sensing theory using a Total Variation (TV) norm to ...
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Role of the Scavenger Receptor CD36 in Accelerated Diabetic Atherosclerosis
... macrophages, vascular smooth muscle cells (VSMC) also play a decisive and, probably, understudied role. VSMC-derived foam cells in human atherosclerotic lesions are well documented [4,5], with recent studies showing that ...
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Nicolaou, Alexandros (2019): Identification of novel atherosclerosis modifiers in mice. Dissertation, LMU München: Medizinische Fakultät
... to atherosclerosis. Three different atherosclerosis mouse models are used to induce and examine ...induce atherosclerosis in wild-type mice ...of atherosclerosis when fed a high-cholesterol ...
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