Acinar cell
Preexisting pancreatic acinar cells contribute to acinar cell, but not islet β cell, regeneration
... pancreatic acinar cells can serve as progenitors for pancreatic islets, a concept with substantial implications for therapeutic efforts to increase insulin- producing b cell mass in patients with ...
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A primary pure pancreatic-type acinar cell carcinoma of the stomach: a case report
... Although, pancreatic neoplasms can occur in any of the sites where heterotopic pancreatic tissue is present, the incidence of extrapancreatic pancreatic-type neoplasms is very rare; most are ductal adenocarcinomas and ...
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Loss of acinar cell IKKα triggers spontaneous pancreatitis in mice
... pancreatic acinar cells (31) or pancreas-specific ablation of the RelA gene ...in acinar cells can cause pan- creatitis (31), insufficient NF-κB activity sensitizes acinar cells to cerulein-induced ...
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The BRG1/SOX9 axis is critical for acinar cell–derived pancreatic tumorigenesis
... established acinar cell–originated PanIN-derived PDA in a con- text-dependent manner, similar to what has been seen during IPMN formation and established IPMN-derived PDA ...
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A resected case of symptomatic acinar cell cystadenoma of the pancreas displacing the main pancreatic duct
... Acinar cell cystadenoma (ACA) of the pancreas has been newly recognized as an entity by the World Health Organization (WHO) definition (2010), and its pathogenesis has not been known adequately because of ...
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Notch inhibits Ptf1 function and acinar cell differentiation in developing mouse and zebrafish pancreas
... from acinar cluster, indicated by broken ...Hes1-negative acinar cell, identified by basal nuclei and apical collection of amylase-positive zymogen ...
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A comparison study of pancreatic acinar cell carcinoma with ductal adenocarcinoma using computed tomography in Chinese patients
... Abstract: Pancreatic acinar cell carcinoma (ACC) is a rare tumor that is difficult to diagnose preoperatively. The aim of this study was to evaluate and describe the computed tomography (CT) features of ACC ...
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Original Article ER stress is associated with pancreatic acinar cell injury induced by nicardipine
... Since nicardipine activated trypsinogen activa- tion in vitro, we questioned whether it could cause damage to acinar cell injury in vivo. C57BL/6 mice were used to investigate the tox- icity of nicardipine. ...
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Original Article Clinical characteristics, therapy and prognosis of parotid acinar cell carcinoma
... Received February 19, 2016; Accepted May 15, 2016; Epub January 15, 2017; Published January 30, 2017 Abstract: Objective: This study was aimed to investigate the clinical characteristics, therapy and prognosis of parotid ...
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Curative resection of a primarily unresectable acinar cell carcinoma of the pancreas after chemotherapy
... In the histology of the tissue, the normal acinic structure of the exocrine pancreas was effaced. The irregularly shaped tumor cells with eosinophilic cytoplasm had rounded dark nuclei and were growing in solid sheets. ...
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Effect of Momordica charantia L. on serum biochemical parameters in experimentally induced atypical acinar cell tumors in male wistar rats
... The present investigation was carried out to study the effect of Momordica charantia L. (Bitter gourd) on serum biochemical parameters in male wistar rats induced with pancreatic atypical acinar cell tumor. ...
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Surgical resection of hepatic and rectal metastases of pancreatic acinar cell carcinoma (PACC): a case report
... Pancreatic acinar cell carcinoma (PACC), a rare variant of pancreatic malignancy, is generally managed the same way as pancreatic ductal adenocarcinoma ...
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Novel patient derived xenograft mouse model for pancreatic acinar cell carcinoma demonstrates single agent activity of oxaliplatin
... pancreatic acinar cell carcinoma (PACC) PDTX mouse model, was derived from a metastatic liver biopsy of a patient previously described in a case report ...solid, acinar-like growth pattern by cells ...
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Acinar Cell Carcinoma of the Pancreas with Colon Involvement
... Acinar cell carcinoma of the pancreas (ACC) is a rare malignant epithelial tumor representing 1-2% of all exocrine pancreatic neoplasms [1]. Symptoms such as weight loss, abdominal pain, nausea, and ...
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Acinar cell carcinoma: a report of 19 cases with a brief review of the literature
... of acinar cell carcinoma of the pancreas, and 19 patients with pathologically con- firmed ACC were enrolled, while 19 conventional DCAs assigned randomly as ...
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Effects of caerulein on the apical cytoskeleton of the pancreatic acinar cell
... In control acini and acini stimulated with concentrations of caerulein up to 0.1 nM, the micrographs reveal an apical actin network extending into microvilli, an intermediate filament ba[r] ...
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Acinar cell carcinoma of exocrine pancreas in two horses
... Neoplastic cells were organized mainly in acinar, and less frequently tubular or solid.. The stroma was fibrous and moderately thick, showing multifocal.[r] ...
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Porphyromonas gingivalis Induced GEF Dock180 Activation by Src/PKCδ Dependent Phosphorylation Mediates PLCγ2 Amplification in Salivary Gland Acinar Cells: Modulatory Effect of Ghrelin
... gland acinar cells to incubation with ...the acinar cell activity of Rac1 GEF, DOck180 and PLC, as well as the membrane localization of Rac1 and ...
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Surgical and molecular pathology of pancreatic neoplasms
... small acinar units or sheets without a distinctive architecture ...[5]. Acinar cell carcinomas express pancreatic exocrine enzymes such as trypsin, chymotrypsin and lipase that can be detectable by ...
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Matrix metalloproteinase 7 is expressed by pancreatic cancer precursors and regulates acinar to ductal metaplasia in exocrine pancreas
... the acinar cell apoptosis and ductal metaplasia observed after PDL were dependent on FasL activity, we performed PDL on gld mice, which carry an inactivating point mutation of FasL ...few acinar ...
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