acinar cells
Expression of Ca2+ dependent Synaptotagmin Isoforms in Mouse and Rat Parotid Acinar Cells
... min in a shaking incubator at 37 and 60 rpm. The carbachol concentrations were followed in a dose-dependent manner. Acinar cells were lysed by sonication. The lysates were clarified by cen- trifugation at ...
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Adaptive respiratory response of rat pancreatic acinar cells to mitochondrial membrane depolarization
... pancreatic acinar cells depends on oxidative substrate: rhodamine123-stained pancreatic acini before (A ) and after 1 min of incubation with 2 μM FCCP ( B ), oxidative substrate – glucose (10 mM); C–F – ...
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Spatial aspects of Ca2+ signalling in pancreatic acinar cells
... pancreatic acinar cells are grouped together and are joined by tight junctions into larger multicellular ...some cells are thought not to possess secretagogue receptors but, nevertheless, Ca 2+ ...
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Organotypic culture of acinar cells for the study of pancreatic cancer initiation
... duct-like cells was attributed to inevitable contamination (and subsequent expansion) of cells endowed with higher proliferative capacity ...exocrine cells from adult mouse pancreas undergo ...
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Physiological and pathological intracellular calcium release in human and murine pancreatic acinar cells
... Single acinar cells and acinar cell clusters were isolated by a method adapted and modified from the rodent work outlined above. Briefly the section of pancreatic tissue was manually dissected using ...
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Enhanced proliferation of pancreatic acinar cells in MRL/ MpJ mice is driven by severe acinar injury but independent of infammation
... pancreatic acinar cells have the ability to re-enter the cell cycle and proliferate upon injury or tissue ...of acinar proliferation is often limited and unable to completely regenerate the injured ...
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Adult pancreatic acinar cells give rise to ducts but not endocrine cells in response to growth factor signaling
... cells for diabetic patients has sparked considerable interest in finding ways to develop increased numbers of cells either in vivo or in ... cells can replicate to increase cell mass (Dor et ...
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Original Article Interleukin-1β induces autophagy by affecting calcium homeostasis and trypsinogen activation in pancreatic acinar cells
... The conversion of the ATG protein microtubule- associated protein 1 light chain 3 (LC3) from its soluble form, LC3-I, to its PE-conjugated form, LC3-II, is considered to be a hallmark of autoph- agy. This conversion can ...
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Constitutive IKK2 activation in acinar cells is sufficient to induce pancreatitis in vivo
... mononuclear cells via the induction of pro- inflammatory cytokines ...inflammatory cells in acinar cells, as assessed by histological and immunohistochemical analyses and iNOS ...
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Cross talk between calcium and cAMP dependent intracellular signaling pathways Implications for synergistic secretion in T84 colonic epithelial cells and rat pancreatic acinar cells
... various cells with combinations of agents that increase either cAMP or cytosolic calcium can lead to synergistic ...epithelial cells and rat pancreatic acinar ...chambers. Acinar cell ...
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Lycopene inhibits IL-6 expression in cerulein-stimulated pancreatic acinar cells
... Since NF-jB activation is induced by oxidants, the antioxidant effect of lycopene may contribute to inhibition of NF-jB activation and IL-6 expression in pancreatic acinar cells. Lycopene may be beneficial ...
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Action of cholecystokinin and cholinergic agents on membrane bound calcium in dispersed pancreatic acinar cells
... dispersed acinar cells prepared from guinea pig pancreas, cellular uptake of 45Ca was moderately rapid and reached a steady state by 60 ...In acinar cells preloaded with 45Ca and then ...
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Luminal endocytosis and intracellular targeting by acinar cells during early biliary pancreatitis in the opossum
... anesthetized animals at physiological pressure. Tissue samples obtained at intervals of up to 60 min after instillation of markers were studied by electron microscopy and electron microscope autoradiography. All markers ...
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Action of cholecystokinin and cholinergic agents on calcium transport in isolated pancreatic acinar cells
... The cholinergic antagonist atropine 10O M did not alter basal calcium outflux in isolated pancreatic acinar cells or the stimulation of calcium outflux produced by CCK-octapeptide, but a[r] ...
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Activation of ERK1/2 by Store-Operated Calcium Entry in Rat Parotid Acinar Cells
... in cells treated with MEK inhibitors that blocked ERK1/2 ...parotid acinar cells: the entry of Ca 2+ into cells in which Ca 2+ stores were first depleted by TG (as in Figure 8) was not ...
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Ionic bases of resting and action potentials in salivary gland acinar cells of the snail Helisoma
... Helisoma salivary gland acinar cells exhibit action potentials with a major dependence on external Ca ions and an apparently small contribution by an inward Na current.. These dependenci[r] ...
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Coxsackievirus Infection Induces Autophagy-Like Vesicles and Megaphagosomes in Pancreatic Acinar Cells In Vivo
... culture cells (93); the reason for this apparent discrepancy is unclear but may reflect major differences between the experi- mental systems (tissue culture cells versus pancreatic tissue in ...bright) ...
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Preexisting pancreatic acinar cells contribute to acinar cell, but not islet β cell, regeneration
... pancreatic acinar cells can serve as progenitors for pancreatic islets, a concept with substantial implications for therapeutic efforts to increase insulin-producing β cell mass in patients with dia- ...
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Beta adrenergic upregulation of the Na(+) K(+) 2Cl cotransporter in rat parotid acinar cells
... these cells, consistent with the involvement of protein kinase ...the acinar Na(+)-K(+)-2Cl- cotransporter would lead to an increase in acinar chloride uptake across the basolateral membrane, and ...
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Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors
... in acinar cells with dispersed clusters of acini, cystic ducts and an apparent absence of endocrine islets in mutant pancreata at ...expressing cells (see ...expressing cells (see ...with ...
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