ACTH-(11–24)
Plasma ACTH, α-MSH and cortisol variations in the dog during the oestrous cycle in different photoperiods
... to ACTH; on the other hand, it is possible that E 2 in female dogs has a regulatory effect over the fascicular zone of the adrenal cortex, as in other species (Viau and Meaney 1991; van Lier et ...of ACTH ...
11
Severe Cushing’s syndrome and bilateral pulmonary nodules: beyond ectopic ACTH
... Cushing’s syndrome is a rare disease that results from prolonged exposure to supraphysiological levels of glucocorticoids. Severe and rapidly progressive cases are often, but not exclusively, attributable to ectopic ...
6
Resistant Nephrotic Syndrome: Review of Trials Using ACTH and a Case Series of Six Patients Treated with ACTHar
... of ACTH (cosyntropin-ACTH 1-24) and ACTHar (ACTH1-39), a synthetic gel isolated from porcine pituitary extracts, have been used successfully in treating NS but fewer than 100 published cases of ...
5
A complex mechanism of facilitation in pituitary ACTH cells: recent single cell studies
... Dynamics of CRH-induced ACTH secretion Pituitary ACTH cells corticotropes respond to corticotropin releasing hormone CRH with sustained ACTH release in the sustained presence of the stim[r] ...
18
Radioimmunoassay of ACTH in plasma
... Techniques are described in detail for a radioimmunoassay of plasma adrenocorticotropin (ACTH) that is capable of detecting hormone in unextracted normal human plasma at 1:5 dilution under the conditions ...
28
THERAPEUTIC EFFECTS OF ACTH AND CORTISONE IN RHEUMATIC FEVER: CARDIOLOGIC OBSERVATIONS IN A CONTROLLED SERIES OF 100 CASES
... FEVER: CARDIOLOGIC OBSERVATIONS IN A CONTROLLED SERIES OF 100 THERAPEUTIC EFFECTS OF ACTH AND CORTISONE IN RHEUMATIC. http://pediatrics.aappublications.org/content/17/1/11[r] ...
20
OBSERVATIONS DURING ACTH AND CORTISONE ADMINISTRATION TO A PATIENT WITH LONGSTANDING PANHYPO PITUITARISM AND RHEUMATOID ARTHRITIS
... The opportunity to observe the effect of administration of pituitary adrenocorticotrophic hormone ACTH and 11-dehydro-17-hydroxycorticosterone cortisone on the moderately active rheumato[r] ...
8
Biologic and Immunologic Characterization and Physical Separation of ACTH and ACTH Fragments in the Ectopic ACTH Syndrome
... bioactive ACTH eluted in the same fractions as pituitary ACTH (mol wt 4,500 daltons) and reacted equally in all three ACTH radioimmunoassay ...tumor ACTH was neutralized by incubation with the ...
15
ACTH IN THE TREATMENT OF ERYTHROBLASTOSIS
... A more desirable method of treatment might be the institution of ACTh at birth fol- lowed by exchange transfusion for only those infants who show an alarming rise in serum bilirubin or a[r] ...
11
ACTH, CORTISONE AND ALLIED SUBJECTS
... Complications of ACTH administration in children with the nephrotic syndrome include: 1. metabolic disturbances: hypotonicity of the extracellular fluid accompanied by low serum potassiu[r] ...
8
ACTH and prostaglandin receptors in human adrenocortical tumors Apparent modification of a specific component of the ACTH binding site
... to ACTH was investigated in vivo be administration of corticotropin-(1-24)-tetracosapeptide (ACTH1-24) and dexamethasone and in vitro by studying the binding properties of ACTH1-24 and ...
13
HEREDITARY ADRENOCORTICAL UNRESPONSIVENESS TO ACTH
... Investigations between 3 and 4 years of age in the female proband re- vealed that plasma ACTH values determined by both radioimmunoassay and bioassay were greatly elevated.. However, sub[r] ...
8
PITUITARY ADRENOCORTICOTROPIC HORMONE (ACTH) AND 11-DEHYDRO-17 HYDROXY CORTICOSTERONE (CORTISONE) THERAPY IN THE LEUKEMIAS AND LYMPHOMAS OF CHILDREN
... marrow was not as clear as that between uric acid excretion and the destruction of periph- eral- leukemic cells, these two effects do appear to be related.. The marrow blast cells.[r] ...
14
Disordered Adrenocorticotropin Secretion in Women with Major Depression
... to ACTH and cortisol se- cretion data from 24 pairs of depressed women and age- and menstrual cycle day-matched controls to determine whether the regularity of ACTH and cortisol secretion and ...
5
Excess corticotropin releasing hormone binding protein in the hypothalamic pituitary adrenal axis in transgenic mice
... In this study, we have generated transgenic mice that produce high levels of CRH-BP within the anterior pituitary to study the role that pituitary CRH-BP plays in regulating CRH activ- ity within the HPA axis. We ...
10
Angiotensin II infusion in vivo does not modulate cortisol secretion in the late gestation ovine fetus
... (4). ACTH-(1—24) (Synacthen, Ciba Geigy Australia, Pendle Hill, NSW, Australia; ...before ACTH-(1—24) injection (time 0); and at 10, 30, 60, 90, and 120 min after ACTH-(1—24) ...
7
Abnormal hormone responses of an adrenocortical cancer adenyl cyclase
... thyrocalcitonin. ACTH was the only hormonal preparation that stimulated normal adrenal ...for ACTH or with the possibility that the tumor possesses several cyclase regulatory ...
7
PRKAR1A negative familial Cushing’s syndrome: two case reports
... His blood tests excluded diabetes mellitus and electro- lyte abnormalities. His hormone tests revealed sup- pressed ACTH (<5 pg/ml) and failed suppression of endogenous plasma cortisol after 1-mg overnight ...
8
Stimulation of gonadal steroid synthesis by chronic excess of adrenocorticotropin in patients with adrenocortical insufficiency
... and 11-ketoandrosterone) was markedly ...of 11 beta-hydroxyandrosterone was confirmed by mass-spectrometry in the urine of three ...of ACTH apparently stimulate early steps of steroid synthesis, most ...
9
CORTICOTROPIN AND STEROID HORMONE THERAPY OF ALLERGIC STATES IN CHILDREN
... ACTH and cortisone imi the treatment of asthma and eczema in infancy and child- hood. : ACTH in atopic dermatitis[r] ...
10