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actin cytoskeleton

A DOCK8 WIP WASp complex links T cell receptors to the actin cytoskeleton

A DOCK8 WIP WASp complex links T cell receptors to the actin cytoskeleton

... actin cytoskeleton. The spatial proximity of DOCK8, WASp, and actin in this complex ensures that CDC42 activated by DOCK8 following TCR liga- tion drives WASp-mediated actin polymerization, as ...

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Caldesmon regulates the motility of vascular smooth muscle cells by modulating the actin cytoskeleton stability

Caldesmon regulates the motility of vascular smooth muscle cells by modulating the actin cytoskeleton stability

... the actin- binding sites at the C-terminal region of CaD, thereby decreasing its effectiveness of actin binding, as well as its stabilizing action on the actin ...

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Vincristine alleviates adriamycin-induced nephropathy through stabilizing actin cytoskeleton

Vincristine alleviates adriamycin-induced nephropathy through stabilizing actin cytoskeleton

... Intact actin cytoskeleton is essential to maintain the normal physiology and unique morphol- ogy of ...induces actin fiber depo- lymerization of podocyte and thereby disrupt its normal ...the ...

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Modulation of the Actin Cytoskeleton via Gelsolin Regulates Vacuolar H+ ATPase Recycling

Modulation of the Actin Cytoskeleton via Gelsolin Regulates Vacuolar H+ ATPase Recycling

... the actin cytoskeleton in regulating clathrin-mediated endocytosis is clearly emerging (20, 63), its role in the recycling of V- ATPase, which utilizes unique clathrin- and caveolin-inde- pendent mechanisms ...

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Dynein and the actin cytoskeleton control kinesin driven cytoplasmic
streaming in Drosophila oocytes

Dynein and the actin cytoskeleton control kinesin driven cytoplasmic streaming in Drosophila oocytes

... The actin cytoskeleton also has an important role in repressing premature fast ...the actin regulators Cappuccino, Spire or Chickadee (profilin) are compromised by genetic mutations (Emmons et ...

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Actin cytoskeleton of rabbit intestinal cells is a target for potent marine phycotoxins

Actin cytoskeleton of rabbit intestinal cells is a target for potent marine phycotoxins

... them cytoskeleton modifications (Yin and Stossel, 1979; Puius et ...on actin cytoskeleton is highly related to Ca 2+ influx, which would be consistent with recent reports suggesting that the toxic ...

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Actin Cytoskeleton Is Involved in Targeting of a Viral Hsp70 Homolog to the Cell Periphery

Actin Cytoskeleton Is Involved in Targeting of a Viral Hsp70 Homolog to the Cell Periphery

... It seems likely that trafficking of the viral proteins, genomes, and particles within and between cells relies on preexisting pathways of intercellular communication used by host NCAPs (31). It will be interesting to see ...

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Alphaherpesviral US3 Kinase Induces Cofilin Dephosphorylation To Reorganize the Actin Cytoskeleton

Alphaherpesviral US3 Kinase Induces Cofilin Dephosphorylation To Reorganize the Actin Cytoskeleton

... the actin cytoskeleton, including disassembly of actin stress fibers and formation of cellular projections, which are associated with increased viral spread in cell culture ...the actin ...

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Overexpression of Translation Elongation Factor 1A Affects the Organization and Function of the Actin Cytoskeleton in Yeast

Overexpression of Translation Elongation Factor 1A Affects the Organization and Function of the Actin Cytoskeleton in Yeast

... the actin suggest that overexpression of eEF1A may directly affect cytoskeleton, because mammalian protein synthesis re- the actin cytoskeleton and that the growth defects seen quires an ...

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CAPZA1 modulates EMT by regulating actin cytoskeleton remodelling in hepatocellular carcinoma

CAPZA1 modulates EMT by regulating actin cytoskeleton remodelling in hepatocellular carcinoma

... including cytoskeleton remodelling as well as changes in gene expression and cellular ...process, actin filament assembly plays an important role in maintaining the morphology and movement of tumour ...an ...

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A Cdc42 regulated actin cytoskeleton mediates Drosophila oocyte polarization

A Cdc42 regulated actin cytoskeleton mediates Drosophila oocyte polarization

... The Par proteins are conserved key players in cell polarity and maintenance and were first identified in Caenorhabditis elegans. Whereas symmetry breaking and thus axis establishment in the C. elegans embryo are ...

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Girdin mediated interactions between cadherin and the actin cytoskeleton are required for epithelial morphogenesis in Drosophila

Girdin mediated interactions between cadherin and the actin cytoskeleton are required for epithelial morphogenesis in Drosophila

... In conclusion, our study suggests that Girdin is required for epithelial tissue morphogenesis and integrity. Specifically, Girdin coordinates collective cell migration, a function that probably depends on the ability of ...

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Identification of Functional Connections Between Calmodulin and the Yeast Actin Cytoskeleton

Identification of Functional Connections Between Calmodulin and the Yeast Actin Cytoskeleton

... gene was found to be identical to MNN10/SLC2/BED1 We found here that among the complementing muta- (mannan defective/synthetic lethality with cap2/bud tions, only cmd1-226 (F92A) exhibits synthetic lethal emergence ...

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A Role for GEA1 and GEA2 in the Organization of the Actin Cytoskeleton in Saccharomyces cerevisiae

A Role for GEA1 and GEA2 in the Organization of the Actin Cytoskeleton in Saccharomyces cerevisiae

... and actin cytoskeleton in gea2⌬, gea1-4 gea2⌬, and gea1-6 gea2⌬ ...(C) Actin cytoskeleton in gea2⌬, gea1-4 gea2⌬, and gea1-6 gea2⌬ ...hr. Actin distribution was visualized with FITC- or ...

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Adenovirus Endocytosis Requires Actin Cytoskeleton Reorganization Mediated by Rho Family GTPases

Adenovirus Endocytosis Requires Actin Cytoskeleton Reorganization Mediated by Rho Family GTPases

... the cytoskeleton-associated Rac mutant (F37A) significantly decreased Ad ...the actin cytoskeleton rather than activation of the JNK/MAP kinase pathway plays the major role in Ad ...cell actin ...

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Loss of glomerular foot processes is associated with uncoupling of podocalyxin from the actin cytoskeleton

Loss of glomerular foot processes is associated with uncoupling of podocalyxin from the actin cytoskeleton

... including nephrin, CD2AP, podocin, α-actinin4, α3β1 integrin, and laminin β 2, also lead to disruption of podocyte architecture and the nephrotic syndrome. Mutations in the nephrin gene, a component of the slit diaphragm ...

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R : Actin cytoskeleton–dependent regulation of corticotropin releasing factor receptor heteromers

R : Actin cytoskeleton–dependent regulation of corticotropin releasing factor receptor heteromers

... of actin cytoskeleton in polarized Caco2 cells inhibits receptor-mediated en- docytosis at the apical but not the basolateral surface (Gottlieb et ...of actin filaments controls formation of ...

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N terminal Slit2 inhibits HIV 1 replication by regulating the actin cytoskeleton

N terminal Slit2 inhibits HIV 1 replication by regulating the actin cytoskeleton

... regulates actin polymerization after binding to Robo receptor ...in actin cytoskeleton ...trigger actin cytoskeletal rearrangements facilitating viral entry ...

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A role for the actin cytoskeleton of Saccharomyces cerevisiae in bipolar bud-site selection

A role for the actin cytoskeleton of Saccharomyces cerevisiae in bipolar bud-site selection

... ther actin or actin-associated proteins perturb the bipolar bud-site selection ...in actin cyto- skeleton mutants reflect a direct role of the actin cytoskel- eton in placement of budding cues ...

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Injury-induced actin cytoskeleton reorganization in podocytes revealed by super-resolution microscopy

Injury-induced actin cytoskeleton reorganization in podocytes revealed by super-resolution microscopy

... thick actin cables in the major processes contain myosin IIA and α-actinin-4 in an alternating fashion and are therefore, by definition, contractile actin fibers, while the actin cables in the foot ...

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