Activating transcription factor 3 (ATF3)
Original Article Effect of overexpression of activating transcription factor 3 on biological behaviors of human colorectal cancer HCT116 cells
... worldwide. Activating transcription factor 3 (ATF3) has been identified as both an oncogene and a tumor sup- pressor in colorectal cancer, which encourages further studies to validate ...
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The induction of activating transcription factor 3 (ATF3) contributes to anti cancer activity of Abeliophyllum distichum Nakai in human colorectal cancer cells
... of activating transcription factor 3 (ATF3) has been known to exert a proapoptotic effect in human colorectal cancer [8-10] and ATF3 is a major target of some anticancer drugs ...
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Activating transcription factor 3 modulates protein kinase C epsilon activation in diabetic peripheral neuropathy
... whether activating transcription factor 3 (ATF3) is responsible for neuronal injury and a critical molecule that modulates the activation of intracellular protein kinase C epsilon ...
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Contribution of Activating Transcription Factor 3 to development of acinar-to-ductal cell metaplasia
... for activating transcription of various factors required to induce cell functions such as cell survival or ...in activating transcription of NFκB and JUN (Chang et ...in ATF3 signalling ...
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The Biology and Regulation of Activating Transcription Factor 3 (ATF3) by Nonsteroidal Anti-inflammatory Drugs (NSAIDs) and Dietary Compounds with Chemopreventive Activity.
... regarding ATF3 in colorectal cancer ...cells, ATF3 is induced by ionizing radiation by a p53-dependent mechanism, and that this effect did not occur in RKO-E6 (etoposide resistant) cells ...Furthermore, ...
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Anti cancer activity of Ginger (Zingiber officinale) leaf through the expression of activating transcription factor 3 in human colorectal cancer cells
... The 3- (4,5-dimethylthizaol-2-yl)-2,5-diphenyl tetrazolium brom- ide (MTT) and SP600125 was purchased from Sigma Aldrich ...USA). ATF3 antibody and ATF3 siRNA were provided from Santa Cruz ...
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Urinary exosomal activating transcriptional factor 3 as the early diagnostic biomarker for sepsis-induced acute kidney injury
... [17–19]. Activating transcription factor 3 (ATF3) is one of the transcriptional factor protected inside urine exosome which expressed in urine of AKI in patients and animal ...
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Low pH results in co ordinate regulation of gene expression in oesophageal cells
... accelerating factor (DAF) was observed, which has previously been reported to be upregu- lated in BO ...The transcription factors FOSB and JUN of the AP-1 transcription complex, known to have ...
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Berberine regulates the protein expression of multiple tumorigenesis-related genes in hepatocellular carcinoma cell lines
... Kruppel-like factor 6 (KLF6) [21, 22], activating transcription factor 3 (ATF3) [23], and the cyclin-dependent kinase inhibitor protein p21 [24] have been found to be reduced in ...
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Herpesviruses and the Unfolded Protein Response
... initiation factor, eIF2α ...bZIP transcription factor Activating Transcription Factor 4 ...of transcription factors and can bind to ATF/CRE-like sequences with a consensus ...
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Transcription factor ATF3 links host adaptive response to breast cancer metastasis
... identified activating transcription factor 3 (ATF3) as a molecule that regulated the host response and con- tributed to the co-option of the host by cancer cells to promote ...
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Uncovering Dual Roles for PERK Signaling During Experimentally Induced Pancreatitis
... members Activating Transcription Factor (ATF) 3 and stanniocalcin (STC) ...of ATF3 and STC2 within the context of PERK signaling and pancreatitis are not well ...and ATF3 during ...
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Transcriptomic and ChIP-sequence interrogation of EGFR signaling in HER2+ breast cancer cells reveals a dynamic chromatin landscape and S100 genes as targets
... (i.e. transcription factors) or through their ...what transcription factor binding sites are present at the various regulated clusters of genes we analyzed the window from − 300 to + 50 of all ...
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Activating transcription factor-4 promotes mineralization in vascular smooth muscle cells
... The ATF4-C/EBPβ complex regulates transcription of PiT1 and PiT2 genes. Since ATF4 is a pleiotropic tran- scription factor, we next proceeded to locate the ATF4 response element (ATF4RE) in the PiT1 gene ...
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Activating transcription factor 5 enhances radioresistance and malignancy in cancer cells
... (radius of 17.5 mm) filled with 500 μL of collagen gel. 1 day after seeding, 250 μL of collagen sol solution was poured on the cells and incubated for approximately 30 min at 37°C to induce gelation. The dish was then ...
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Activating transcription factor 4 regulates osteoclast differentiation in mice
... ATF4 is upregulated by M-CSF and PI3K/AKT and is required for M-CSF induction of RANK expression in BMMs. (A and B) Effects of M-CSF on ATF4 in BMMs. Cells were cultured with or without 30 ng/ml M-CSF for the indicated ...
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Activating transcription factor 6 derepression mediates neuroprotection in Huntington disease
... The footprint test was used to compare the gait of R6/2 transgenic with that of WT control mice. To obtain footprints, mouse hind and forepaws were coated with blue and red nontoxic paints, respective- ly. Mice were then ...
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Cullin-RING ligases in regulation of autophagy
... Ambra1: activating molecule in Beclin-1-regulated autophagy; AMPK: AMP-activated protein kinase; ATF4: activating transcription factor 4; ATG: autophagy related gene; Bcl-2: B-cell lymphoma 2; ...
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Dysfunction of various organelles provokes multiple cell death after quantum dot exposure
... regulate transcription of downstream genes such as Bip/ GRP78 and other cytoprotective genes, accelerating the ubiquitination of misfolded proteins through ER-assisted ...initiation factor 2 α , followed by ...
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Li, He (2017): APC/C independent function of the spindle assembly checkpoint. Dissertation, LMU München: Fakultät für Biologie
... checked transcription of CLB2-cluster genes in cells lacking another essential SAC gene MAD1 (Figure ...Although transcription of CLB2-cluster genes was strongly induced in MAD1 cells, transcriptional ...
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