Activating transcription factor 5
Differential expression of two activating transcription factor 5 isoforms in papillary thyroid carcinoma
... Background: Activating transcription factor 5 (ATF5) is a member of the activating transcription/cAMP response element-binding protein family of basic leucine zipper proteins ...
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Activating transcription factor 5 enhances radioresistance and malignancy in cancer cells
... with 5% CO 2 ...vitro transcription T7 kit (Takara, Otsu, ...follows: 5′-CAAAAATAAAACGAAACATTT-3′ for ATF5, 5′-CAAAGTTTGAAGAAATATACC-3′ for cyclin A2, and 5′-CAAGGAAAAGACATACTTAAG-3′ ...
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Expression of activating transcription factor 5 (ATF5) is increased in astrocytomas of different WHO grades and correlates with survival of glioblastoma patients
... For an assessment of the putative prognostic significance of the ATF5 expression level on the clinical course of the 42 GBM patients with complete clinical data, we divided our patient cohort into two groups (each n = ...
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The HLA B*35 allele modulates ER stress, inflammation and proliferation in PBMCs from Limited Cutaneous Systemic Sclerosis patients
... Arachidonate 5- lipoxygenase-activating protein; ATF4: activating transcription factor 4; BiP/ GRP78: glucose regulated protein; C1QC/C1QB: complement component 1, q subcomponent, C / B ...
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The role of death receptors in ER stress and Inflamation
... exchange factor that recycles it to its active GTP bound form (Harding et ...the 5’ untranslated regions. The bZIP, ER stress-associated activating transcription factor 4 (ATF4) is an ...
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Activating transcription factor 6 derepression mediates neuroprotection in Huntington disease
... (PBS, 5 mM DTT, 1 mM EDTA, Complete Mini EDTA-free protease inhibitors [Roche]) for 2 hours with rotation at ...with 5% BSA overnight at 4°C, washed with binding buffer, and recon- stituted in pull-down ...
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Herpesviruses and the Unfolded Protein Response
... initiation factor, eIF2α ...the 5’UTR of their mRNAs ...bZIP transcription factor Activating Transcription Factor 4 ...of transcription factors and can bind to ...
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Activating transcription factor-4 promotes mineralization in vascular smooth muscle cells
... and activating transcription factor 6 (ATF6) implement the ER stress response ...initiation factor 2 (eIF2α), which inhib- its assembly of the 80S ribosome and protein ...its ...
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Contribution of Activating Transcription Factor 3 to development of acinar-to-ductal cell metaplasia
... dissolved 5% non-fat dried milk (NFDM) in PBS for 60 ...for 5 minutes each before incubating with primary ...in 5% NFDM in PBS, where as phosphorylated-ERK1/2 (1:500; Cell Signaling Technology, ...
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Activating transcription factor 4 regulates osteoclast differentiation in mice
... OCL-targeted transgenic overexpression of ATF4 dramatically increases OCL differentiation and bone resorption and results in a severe osteopenic phenotype. (A) Schematic representation of a transgene construct. An ...
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Non-esterified fatty acids in the ovary: friends or foes?
... AMPK: 5 ′ adenosine monophosphate-activated protein kinase; ATF4: Activating transcription factor 4; cAMP: Cyclic adenosine monophosphate; CCND2: Cyclin D2; CLA: Conjugated linoleic acid; COC: ...
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Low pH results in co ordinate regulation of gene expression in oesophageal cells
... accelerating factor (DAF) was observed, which has previously been reported to be upregu- lated in BO ...The transcription factors FOSB and JUN of the AP-1 transcription complex, known to have ...
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Identification potential biomarkers in pulmonary tuberculosis and latent infection based on bioinformatics analysis
... ATF: Activating transcription factor; ATP1A4 : ATPase, Na+/K+ transporting, alpha 4 polypeptide; BATF : Basic leucine zipper transcription factor, ATF-like; BH: Benjamin and Hochberg; ...
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Cullin-RING ligases in regulation of autophagy
... Ambra1: activating molecule in Beclin-1-regulated autophagy; AMPK: AMP-activated protein kinase; ATF4: activating transcription factor 4; ATG: autophagy related gene; Bcl-2: B-cell lymphoma 2; ...
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Myxoma virus attenuates expression of activating transcription factor 4 (ATF4) which has implications for the treatment of proteasome inhibitor–resistant multiple myeloma
... aTF, activating transcription factor; Brea, brefeldin-a; DTT, dithiothreitol; ire1, inositol-requiring protein-1; mrna, messenger rna; MYXV, myxoma virus; Pcr, polymerase chain reaction; PerK, ...
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Synthetic control devices for gene regulation in Penicillium chrysogenum
... and 5 ′ flanking regions for integration upstream to penDE was digested with DraIII before co-transfor- mation with marker-free ...DNA. 5 μg marker-free dDNA cassette carrying plasmid (YN1_81, YN1_82, ...
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Glass confers rhabdomeric photoreceptor identity in Drosophila, but not across all metazoans
... To perform double in situ hybridisation in Platy- nereis, we followed—with few modifications—a proto- col that has been previously used for characterising the expression pattern of r-opsin1 [16, 41]. For the present ...
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Tumor necrosis factor superfamily member APRIL contributes to fibrotic scar formation after spinal cord injury
... Mice were anesthetized as described above and perfused transcardially with cold Dulbecco’s phosphate-buffered saline (DPBS, Gibco 14190-144). Naïve or wild-type (WT) injured mice were used as controls. A 4-mm sec- tion ...
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Altered Cellular mRNA Levels in Human Cytomegalovirus-Infected Fibroblasts: Viral Block to the Accumulation of Antiviral mRNAs
... cellular transcription pathways that are activated and repressed during viral infection could lead to a better understanding of the virus-host interaction and to the identification of targets for antiviral ...
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<p>Inhibition of Migration, Invasion and Drug Resistance of Pancreatic Adenocarcinoma Cells – Role of Snail, Slug and Twist and Small Molecule Inhibitors</p>
... containing 5 µg/mL polybrene (sc-134220, Santa Cruz, ...After 5 days of transfection, GFP was observed, and the medium was changed with a complete medium containing 1 µg/mL puromycin dihydrochloride ...
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