Activator protein-1 (AP-1)
Progesterone receptor assembly of a transcriptional complex along with activator protein 1, signal transducer and activator of transcription 3 and ErbB 2 governs breast cancer growth and predicts response to endocrine therapy
... mitogen-activated protein kinases (MAPKs) [3-5], phos- phatidylinositol 3-kinase (PI-3 K)/Akt [5], and Jaks/signal transducer and activator of transcription 3 (Stat3) [6,7] pathways, which in turn mediate ...
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Activator protein 1 (AP 1) contributes to EpCAM dependent breast cancer invasion
... The AP-1 transcrip- tion factor is a heterodimeric protein composed of pro- teins belonging to the c-Jun, c-Fos, ATF, and JDP families ...[39]. AP-1 is activated in response to a ...
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Caffeic acid phenethyl ester modulates Helicobacter pylori induced nuclear factor kappa B and activator protein 1 expression in gastric epithelial cells
... NF-kB, AP-1 DNA- binding activity and COX-2 expression in gastric epithelial ...and AP-1 is fundamental to the phenotype of all cells engaged in inflammatory ...and AP-1 are ...
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Molecular mechanisms of cell proliferation induced by low power laser irradiation
... factor activator protein-1 ...[104]. AP-1, an downstream kinase of JNK, promotes expression of genes involved in cell survival, proliferation, and ang- iogenesis ...factor ...
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Sulforaphane has opposing effects on TNF alpha stimulated and unstimulated synoviocytes
... AP-1: activator protein-1; ARE: antioxidant response element; ECM: extracellular matrix; ELISA: enzyme-linked immunosorbent assay; FCS: foetal calf serum; FLS: fibroblast-like ...
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How dietary arachidonic- and docosahexaenoic- acid rich oils differentially affect the murine hepatic transcriptome
... oncogene; AP-1, activator protein 1; APP, amyloid beta (A4) precursor protein; bHLH, basic helix-loop helix; BMP2, bone morphogenetic protein 2; bZIP, basic region- ...
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RETRACTED ARTICLE: Molecular mechanisms in progression of HPV-associated cervical carcinogenesis
... serine/threonine-specific protein kinase; AP-1: Activator protein 1; Bcl- 2: B-cell lymphoma 2; BRD4: Bromodomain-containing protein 4; CADM1: Cell adhesion molecule ...
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Molecular mechanisms of HPV mediated neoplastic progression
... AP-1: Activator protein 1; ATM: Ataxia telangiectasia mutated; ATR: Ataxia telangiectasia and Rad3-related protein; Bax: BCL2-associated X protein; BRCA1: Breast cancer ...
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Intracellular reactive oxygen and nitrogen species as signaling molecules in airway epithelium
... Abbreviations used: AP-1, activator protein 1; ARDS, acute respiratory distress syndrome; BAL, bronchoalve- olar lavage; CAT, catalase; COPD, chronic obstructive pulmonary dise[r] ...
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Anti inflammatory effects of Zea mays L husk extracts
... Background: Zea mays L. ( Z. mays ) has been used for human consumption in the various forms of meal, cooking oil, thickener in sauces and puddings, sweetener in processed food and beverage products, bio-disel. However, ...
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Genomic effects of the vitamin D receptor: Potentially the link between vitamin D, immune cells, and multiple sclerosis
... Abbreviations: AP-1, activator protein 1; ATAC-seq, assay for transposase-acces- sible chromatin using sequencing; C/EBP, CCAAT/enhancer-binding protein; ChIA-PET, chromatin ...
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Myostatin gene promoter: structure, conservation and importance as a target for muscle modulation
... II; AP-1: Activator protein 1; ARE: Androgen receptor element; C/EBP α : CCAAT/enhancer-binding protein- α ; ChoRE: Carbohydrate responsive element; ChREBP: Carbohydrate ...
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Chronic inflammatory diseases are stimulated by current lifestyle: how diet, stress levels and medication prevent our body from recovering
... ANXA 1: Annexin 1 protein; AP-1: Activator protein 1; ASA: Aspirin; ATLs: Stable aspirin-triggered lipoxin; COX: Cyclo-oygenase; CRP: High sensitive-C- Reactive ...
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Regulation of bone by the adaptive immune system in arthritis
... AP-1, activator protein 1; CNS2, conserved noncoding sequence 2; CREB, cyclic adenosine monophosphate responsive-element-binding protein; EAE, experimental autoimmune ...
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Epithelium-specific Ets transcription factor-1 acts as a negative regulator of cyclooxygenase-2 in human rheumatoid arthritis synovial fibroblasts
... COX-2 gene activation is complex and employs numer- ous regulatory factors specific to different stimuli, as exemplified by the COX-2 promoter which contains two NFκB motifs, two activator protein 1 ...
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Role of AP-1 transcriptional factor in development of oxidative and nitrosative stress in periodontal tissues during systemic inflammatory response
... as activator protein 1 (AP-1) in the development of oxidative and nitrosa - tive stress in soft periodontal tissues during chronic systemic inflammatory response ...
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Harmine activates intrinsic and extrinsic pathways of apoptosis in B16F-10 melanoma
... and protein synthesis is a realistic strategy for cancer ...the AP-1 (activator protein-1) family are necessary for cell cycle progression in several cell sys- tems and also for ...
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Molecular regulation of the expression of leptin by hypoxia in human coronary artery smooth muscle cells
... and protein levels increased after ...leptin/activator protein 1 (AP-1) binding and transcriptional activity to the leptin promoter increased after hypoxia, and SP600125, JNK ...
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CCAAT/enhancer binding protein β promotes receptor activator of nuclear factor kappa B ligand (RANKL) expression and osteoclast formation in the synovium in rheumatoid arthritis
... medium; AP-1: activator protein-1; ATF-4: activation transcription factor 4; bp: base pairs; C/EBP: CCAAT/enhancer binding protein; ChIP: chromatin immunoprecipitation; DMEM: ...
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Small-molecule BH3 mimetic and pan-Bcl-2 inhibitor AT-101 enhances the antitumor efficacy of cisplatin through inhibition of APE1 repair and redox activity in non-small-cell lung cancer
... Ki-67 protein, being a marker of tumor cell proliferation, was markedly decreased in the combination therapy group when compared with the monotherapy ...B/ activator ...
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