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Active Crohn’s disease

Pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension with active Crohn’s disease

Pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension with active Crohn’s disease

... in active inflammatory bowel disease (IBD) is challenging because of hypercoagulation and bleeding ...with active Crohns disease successfully treated with pulmonary ...

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Feasibility of high-intensity interval training and moderate-intensity continuous training in adults with inactive or mildly active Crohn’s disease: study protocol for a randomised controlled trial

Feasibility of high-intensity interval training and moderate-intensity continuous training in adults with inactive or mildly active Crohn’s disease: study protocol for a randomised controlled trial

... mildly active Crohns disease will be randomly assigned 1:1:1 to HIIT, MICT or usual care ...of disease activity (faecal calprotectin and Crohns Disease ...

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A case of rapidly progressive IgA nephropathy in a patient with exacerbation of Crohn’s disease

A case of rapidly progressive IgA nephropathy in a patient with exacerbation of Crohn’s disease

... IL-17, a cytokine produced by CD4+ memory T cells, induces the release of pro-inflammatory cytokines from monocytes and macrophages [10,11]. This soluble T cell factor thereby promotes inflammation. Recently, IL-17 was ...

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Managing refractory Crohn's disease: challenges and solutions

Managing refractory Crohn's disease: challenges and solutions

... Abstract: The goals of treatment for active Crohn’s disease (CD) are to achieve clinical remis- sion and improve quality of life. Conventional therapeutics for moderate-to-severe CD include 5-aminosalicylic ...

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Small bowel MR enterography: problem solving in Crohn’s disease

Small bowel MR enterography: problem solving in Crohn’s disease

... for disease activity that clinicians have traditionally used (including the Crohn’s Disease Activity Index [CDAI], C-reactive protein [CRP] and more recently faecal markers such as faecal ...determine ...

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Mean platelet volume: a controversial marker of disease activity in Crohn’s disease

Mean platelet volume: a controversial marker of disease activity in Crohn’s disease

... subjects. Disease activity was assessed by the Crohns Disease Activity ...between active and inactive CD ...of active CD was ...

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Psychological wellbeing and physical activity in children and adolescents with inflammatory bowel disease compared to healthy controls

Psychological wellbeing and physical activity in children and adolescents with inflammatory bowel disease compared to healthy controls

... with active IBD are known to report increased erythrocyte- sedimentation rates (ESR) due to inflammation, decreased hemoglobin due to chronic blood loss in the gut, decreased albumin due to leaking gut at reduced ...

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Infliximab to treat Crohn’s disease: an update

Infliximab to treat Crohn’s disease: an update

... whose disease had been controlled for at least 6 months on maintenance IFX combined with immunosuppressive agents who were randomly assigned to continue or stop the immunosuppressive agents while they continued ...

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Management of Crohn's disease in poor responders to adalimumab

Management of Crohn's disease in poor responders to adalimumab

... Crohn’s disease, with a specific focus on the clinical management of adalimumab ...inflammatory disease activity and rule out noninflammatory ...infliximab. Active inflammation despite therapeutic ...

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Profile of infliximab in the treatment of pediatric Crohn’s disease

Profile of infliximab in the treatment of pediatric Crohn’s disease

... chronically active luminal disease that did not respond to prior optimized immunomodulating therapy, as well as in patients with active steroid-refractory ...with active perianal fis- tulizing ...

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Infliximab therapy in pediatric Crohn’s disease: a review

Infliximab therapy in pediatric Crohn’s disease: a review

... The immunogenicity of infliximab has led to the development of other less immunogenic TNF inhibitory agents, including adalimumab and certolizumab. Adalimumab (fully human anti-TNF) has recently received approval for the ...

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Magnetic resonance enterography in pregnant women with Crohn’s disease: case series and literature review

Magnetic resonance enterography in pregnant women with Crohn’s disease: case series and literature review

... Results: Ten studies of 9 patients were included. MRE protocol was modified to maximize maternal and fetal safety, and intravenous gadolinium was not used. In 7 patients, CD diagnosis was previously established; six were ...

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Measuring disease activity in Crohn's disease: what is currently available to the clinician

Measuring disease activity in Crohn's disease: what is currently available to the clinician

... severe disease or a higher rate of infliximab ...clinically active CD (accord- ing to the CDAI) may have normal CRP levels, and that it may be difficult to know whether such patients really have ...

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Maintenance treatment with infliximab for the management of Crohn’s disease in adults

Maintenance treatment with infliximab for the management of Crohn’s disease in adults

... Crohn’s disease (CD) is a chronic, relapsing disease, the continuous cycle of which deeply affects the long-term course which, eventually, leads to fi brosis and development of transmural ...moderate ...

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Pediatric Crohn's disease: epidemiology and emerging treatment options

Pediatric Crohn's disease: epidemiology and emerging treatment options

... Crohn’s disease remains poorly understood, it is recognized to represent a process of unop- posed inflammation in the ...biologically active molecules mediate this inflam- ...Crohn’s disease and ...

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Magnetic resonance enterography changes after antibody to tumor necrosis factor (anti-TNF) alpha therapy in Crohn’s disease: correlation with SES-CD and clinical-biological markers

Magnetic resonance enterography changes after antibody to tumor necrosis factor (anti-TNF) alpha therapy in Crohn’s disease: correlation with SES-CD and clinical-biological markers

... with active CD, examining patients who underwent ileocolonoscopy and MRI at base- line and 12 weeks after treatment with steroid or tumor ne- crosis factor inhibitor (specifically ...

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A pilot study of transrectal endoscopic ultrasound elastography in inflammatory bowel disease

A pilot study of transrectal endoscopic ultrasound elastography in inflammatory bowel disease

... in active Crohn’s colitis while quite the con- trary ulcerative colitis should be treated first with mesala- zine ...with Crohns colitis can be dele- ...of disease is Table 2 Summary of ...

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Perianal Crohn's disease: challenges and solutions

Perianal Crohn's disease: challenges and solutions

... advancement flaps are the preferred approach for complicated anorectal fistulae without incontinence. Prior to advancement flap, most patients undergo a period of infection control with a draining seton, with or without ...

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Crohn’s disease in women

Crohn’s disease in women

... escent disease at the time of conception have a similar risk for experiencing adverse pregnancy outcomes as the healthy population, while active disease at conception or relapse dur- ing pregnancy ...

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Disease-related information requirements in patients with Crohn’s disease

Disease-related information requirements in patients with Crohn’s disease

... the disease when they cannot see the doctor for some reason, so patients hope to obtain relevant information to help in these ...ing active disease periods, and therefore the demand for information ...

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