Activin and inhibin
Role of inhibin and activin in the modulation of gonadotropin- and steroid-induced oocyte maturation in the teleost Fundulus heteroclitus
... and inhibin are peptides structurally related to the transforming growth factor-β (TGF-β) superfamily of pro- ...termed inhibin A and inhibin ...that activin and inhibin function also ...
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Activin and inhibin in the human adrenal gland Regulation and differential effects in fetal and adult cells
... recombinant activin-A inhibited mitogenesis and enhanced ACTH-stimulated cortisol secretion by cultured fetal zone cells, but not definitive zone or adult adrenal ...Recombinant inhibin-A had no apparent ...
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The glycoprotein-hormones activin A and inhibin A interfere with dendritic cell maturation
... members of the transforming growth factor beta family (TGF-β), namely activin A (ActA) and inhibin A (InA), are present in the serum at dynamic levels during the first tri- mester of human pregnancy [3]. ...
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Transforming growth factor beta family expression at the bovine feto-maternal interface
... including activin and some growth factors participate in this critical event in mice and humans [15-17] but little information is avail- able about this process in ...that activin (gene name: inhibin ...
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Activin signaling as an emerging target for therapeutic interventions
... [79]. Inhibin antagonizes activin by forming a complex of ActRIIs and betaglycan [2,4](Figure ...the activin and BMP pathway are therapeutic targets for the treatment of low bone ...tating ...
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Activin B promotes endometrial cancer cell migration by down- regulating E-cadherin via SMAD-independent MEK-ERK1/2-SNAIL signaling
... importantly, inhibin β subunit expression, activin secretion and activin receptor expression have been demonstrated in neoplastic endometrial tissues and/or endometrial cancer cell lines ...of ...
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Activin-A up-regulates type I activin receptor mRNA levels in human immortalized extravillous trophoblast cells.
... that activin- A stimulates, while inhibin-A inhibits, ActRI mRNA ...by activin-A. The time course of the activin-A ef- fect on ActRI mRNA showed responses at 3 to 12 hours af- ter treatment, ...
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Worbs, Silvia (2008): Expression von Inhibin-alpha, -betaA und -betaB im Endometriumkarzinom: Inhibin-alpha als unabhängiger prognostischer Parameter. Dissertation, LMU München: Medizinische Fakultät
... drei Inhibin/Activin- Untereinheiten in normalen und malignen endometrialem Gewebe gezeigt ...die Inhibin-α-Untereinheit wurde vermehrt in normalem Endometrium im Vergleich zu endometrioiden ...
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Activin a is associated with impaired myocardial glucose metabolism and left ventricular remodeling in patients with uncomplicated type 2 diabetes
... of activin A. Activin A is a dimeric protein consisting of two inhibin βA monomers linked by a single disulfide ...of inhibin βA, and in associ- ation decreased activation of the post-receptor ...
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Activin/Nodal signalling in stem cells
... of Inhibin β , are also expressed in pre- implantation blastocyst but not in the primitive streak (Albano et ...that Inhibin β s are not necessary for early development in the mouse (Lau et ...that ...
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Comparison of follicular fluid and serum levels of Inhibin A and Inhibin B with calculated indices used as predictive markers of ovarian hyperstimulation syndrome in IVF patients
... 10. Nakhuda GS, Chu MC, Wang JG, Sauer MV, Lobo RA: Elevated serum müllerian-inhibiting substance may be a marker for ovarian hyperstimulation syndrome in normal women undergoing in vitro fertilization. Fertil Steril ...
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Reduced quality and accelerated follicle loss with female reproductive aging - does decline in theca dehydroepiandrosterone (DHEA) underlie the problem?
... to inhibin B which plays a critical role in mediating the age-related rise in FSH in older women; neither activin A nor inhibin A seems to show age-related changes ...
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... of Inhibin B was measured using a commercially available solid-phase sandwich enzyme-linked immunosorbent assay (ELISA) specific for the dimeric inhibin-B (Oxford Bio-Innovation ...with activin and ...
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Activin A as an intraovarian modulator: actions, localization, and regulation of the intact dimer in human ovarian cells
... recombinant activin-A and its structural homologue, inhibin-A, on mitogenesis and steroidogenesis (progesterone secretion and aromatase activity) in human preovulatory follicular cells; (b) to localize the ...
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Placenta related pathogenic factors for preeclampsia
... and activin A, are both glycoprotein mainly produced by the syncytiotrophoblast of the human placenta, belong to the TGF-β family ...both Inhibin A and activin A have been shown elevated in women who ...
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... of inhibin and activin in ma- ternal serum which influenced by delivery are un- known for ...of inhibin A in labor at term or ...of Activin A in the ...in inhibin A serum both in ...
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Effects of non steroidal gonadal factors on LH secretion in female common carp during the reproductive cycle
... activins can modify LH levels to a certain extent (Stouffer et al., 1993). Contrary to activin, inhibin decreases the secretion of FSH (Dye et al., 1992). There are increasing numbers of data on the role of ...
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A Secreted Tumor-Suppressor, mac25, with Activin-Binding Activity
... The mac25 protein exhibits strong homology to FS, in particular, with respect to the con- sensus sequence of the Kazal serine protease inhibitor family. The consensus sequence is repeated three times in FS and is also ...
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The FSH-inhibin axis in prader-willi syndrome: heterogeneity of gonadal dysfunction
... and inhibin B levels: hypergonadotrophic (primary gonadal) hypogonadism, hypogonadotrophic (central/hypothalamic) hypogonadism, partial gonadal and central dysfunction and mild central with severe gonadal ...
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The roles of activin and follistatin signaling in chick gastrulation
... Inl J D " lIiol 42 55 1 559 (1998) Original Artirle The roles of activin and follistatin signaling in chick gastrulation MICHAEL LEVIN' Department of Cell Biology Harvard Medical School, Boston, USA A[.] ...
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