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Acute liver failure (ALF)

Protocol based invasive intracranial pressure monitoring in acute liver failure: feasibility, safety and impact on management

Protocol based invasive intracranial pressure monitoring in acute liver failure: feasibility, safety and impact on management

... Acute liver failure (ALF), defined as hepatic encephalop- athy and coagulopathy within 26 weeks of illness onset, is a rare but potentially life-threatening illness ...with ALF may ...

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Peripheral infusion of human umbilical cord mesenchymal stem cells rescues acute liver failure lethality in monkeys

Peripheral infusion of human umbilical cord mesenchymal stem cells rescues acute liver failure lethality in monkeys

... Albumin; ALF: Acute liver failure; ALT: Alanine aminotransferase; APTT: Activated partial thromboplastin time; AST: Glutamic-oxaloacetic transaminase; BA: Blood ammonia; CCR2: C-C chemokine ...

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Acute Liver Failure : Management Update

Acute Liver Failure : Management Update

... Acute liver failure (ALF) is a rare but challenging clinical syndrome with multiple causes; about 50% of pediatric cases a specific etiology cannot be ...of ALF is variable and the ...

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NBAS mutations cause acute liver failure: when acetaminophen is not a culprit

NBAS mutations cause acute liver failure: when acetaminophen is not a culprit

... developed acute-liver-failure with ...to acute-liver-failure even at therapeutic doses, that N-acetylcysteine infusion had been life-saving and should be immediately started in ...

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Human liver organoids generated with single donor-derived multiple cells rescue mice from acute liver failure

Human liver organoids generated with single donor-derived multiple cells rescue mice from acute liver failure

... Alb-TRECK/SCID mice were a gift from the Tokyo Metropolitan Institute of Medical Science. The mice were bred and maintained according to the Yokohama City University institutional guidelines for the use of laboratory ...

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When the heart kills the liver: acute liver failure in congestive heart failure

When the heart kills the liver: acute liver failure in congestive heart failure

... as any observational cohort study, our report has some limitations. First of all we performed a retro- spective study were the findings of such an investiga- tion carry less persuasive force than those of a prospective ...

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Effect of tumor necrosis factor-α on the expression of the ammonia transporter Rhcg in the brain in mice with acute liver failure

Effect of tumor necrosis factor-α on the expression of the ammonia transporter Rhcg in the brain in mice with acute liver failure

... in ALF [24– 27]. Patients with HE who are in ALF have elevated circulating levels of TNF-α ...with liver failure and ...D-GalN/LPS-induced ALF and was corre- lated with Rhcg expression ...

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Progress in mesenchymal stem cell–based therapy for acute liver failure

Progress in mesenchymal stem cell–based therapy for acute liver failure

... of liver failure with MSC transplantation, and the thera- peutic effects of MSC-CM may be the combined effect of free soluble factors and exosomes because both of them have been proven to be effective in ...

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A high prevalence of extreme hyperferritinemia in acute hepatitis patients

A high prevalence of extreme hyperferritinemia in acute hepatitis patients

... underlying acute liver failure (ALF) has not been clarified, recent reports indicate overactivation of macrophages is involved in its ...of ALF, serum ferritin levels might reflect the ...

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Emerging pharmacological tools to control hydrogen sulfide signaling in critical illness

Emerging pharmacological tools to control hydrogen sulfide signaling in critical illness

... sulfurtransferase; ALF: Acute liver failure; AOAA: Aminooxyacetic acid; CARS: Cysteinyl-tRNA synthetase; CAT: Cysteine aminotransferase; CBS: Cystathionine β -synthase; CNS: Central nervous ...

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Human liver stem cells attenuate concanavalin A-induced acute liver injury by modulating myeloid-derived suppressor cells and CD4+ T cells in mice

Human liver stem cells attenuate concanavalin A-induced acute liver injury by modulating myeloid-derived suppressor cells and CD4+ T cells in mice

... Albumin; ALF: Acute liver failure; ALT: Alanine transaminase; AST: Aspartate aminotransferase; BCA: Bicinchoninic acid; CK: Cytokeratin; ConA: Concanavalin A; DMEM: Dulbecco ’ s modified Eagle ...

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Therapeutic efficiency of human amniotic epithelial stem cell-derived functional hepatocyte-like cells in mice with acute hepatic failure

Therapeutic efficiency of human amniotic epithelial stem cell-derived functional hepatocyte-like cells in mice with acute hepatic failure

... and ALF treatment [10, ...for acute liver failure ...treat ALF [18], including tumorigenicity, immune incompatibility between donor and receptor, and ethical issues [19, ...

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Role of Osteopontin in Liver Diseases

Role of Osteopontin in Liver Diseases

... alcoholic liver disease; ALF: acute liver failure; ALT: alanine aminotransferase; APAP: acetaminophen; ASH: alcoholic steatohepatitis; ATP: adenosine triphosphate; Bax: Bcl-2 associated ...

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Primary liver transplantation and liver retransplantation: comparison of health-related quality of life and mental status – a cross-sectional study

Primary liver transplantation and liver retransplantation: comparison of health-related quality of life and mental status – a cross-sectional study

... hypertension; ALF: Acute liver failure; CKF: Chronic kidney failure; DM: Diabetes mellitus; ESLD: End-stage liver disease; GH: General health; HADS: Hospital Anxiety and ...

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Extracorporeal liver support devices for listed patients

Extracorporeal liver support devices for listed patients

... controlled trial of the extracorporeal liver assist device in acute liver failure. Vital Therapies® targeting liver disease[r] ...

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Copeptin in acute decompensation of liver cirrhosis: relationship with acute on chronic liver failure and short term survival

Copeptin in acute decompensation of liver cirrhosis: relationship with acute on chronic liver failure and short term survival

... To date, the prognostic value of copeptin in the setting of liver cirrhosis has been investigated in a few studies [23–26]. The results of these studies show that serum copeptin levels increase along with the ...

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Extracorporeal lung support in trauma patients with severe chest injury and acute lung failure: a 10 year institutional experience

Extracorporeal lung support in trauma patients with severe chest injury and acute lung failure: a 10 year institutional experience

... implantation. Nevertheless, ECMO is a therapy with potentially serious complications [13]. In this study sam- ple, no device-related complications including rupture of the circuits or relevant failure of the ...

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Diurnal variation in the performance of rapid response systems: the role of critical care services—a review article

Diurnal variation in the performance of rapid response systems: the role of critical care services—a review article

... that acute hospital medicine and super-speciality medi- cine are mutually ...provide acute medical care 24 h a day, 7 days a week, for patients who are critic- ally unwell and are at risk of suffering an ...

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EuropePMC-PMC5347641.pdf

EuropePMC-PMC5347641.pdf

... Above all, decreased fatty acid oxidation, increased fatty acid and triglyceride synthesis, increased fat entry into the liver by fatty acid mobilisation from peripheral fat stores and via chylomicrons from the ...

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Hypersensitivity reaction with multi-organ failure following re-exposure to rifampicin: case report and review of the literature including WHO spontaneous safety reports

Hypersensitivity reaction with multi-organ failure following re-exposure to rifampicin: case report and review of the literature including WHO spontaneous safety reports

... Two hours after the first rifampicin dose, the patient presented with dyspnea which proved to be rapidly pro- gressive. On clinical examination the patient was hyper- tensive with a normal heart rate, subfebrile ...

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