acute lymphoblastic leukaemia
Osteonecrosis in patients with acute lymphoblastic leukaemia: a national questionnaire study
... Downloaded from http://bmjpaedsopen.bmj.com/ on April 16, 2018 - Published by group.bmj.com Osteonecrosis in patients with acute lymphoblastic leukaemia: a national questionnaire study N[r] ...
8
Hypereosinophilia in childhood acute lymphoblastic leukaemia at diagnosis: report of 2 cases and review of the literature
... of acute lymphoblastic leukaemia (ALL) and hypereosinophilia represents a distinct clinico-patho- logical entity [2-4], although rarely described in childhood [2,5,6], with 44 paediatric cases ...
5
Investigation of TEL/AML1 and BCR/ABL Fusion Genes in Patients Affected by Acute Lymphoblastic Leukaemia Using Interphase in situ Hybridization
... with acute lymphoblastic leukaemia (ALL), including thirty children and thirty adults were studied by the conventional cytogenetics and fluorescence in situ hybridization (FISH) ...
9
Acute disseminated encephalomyelitis mimicking late CNS relapse of acute lymphoblastic leukaemia: case report
... Her remote clinical history was notable: at age 2 years, she had developed acute lymphoblastic leukaemia (ALL), common B-cell variant. Six months after completing chemotherapy using the UKALLXI ...
5
Genetic and regulatory mechanism of susceptibility to high-hyperdiploid acute lymphoblastic leukaemia at 10p21.2.
... Despite high-hyperdiploid acute lymphoblastic leukaemia (HD-ALL) being the most common subgroup of paediatric ALL, its aetiology remains unknown. Genome-wide association studies have demonstrated ...
9
Study of fingerprints in children under 15 years of age with acute lymphoblastic leukaemia
... of leukaemia will also be excluded from this ...from acute lymphoblastic leukaemia below the age of 15years attending to Indo-American Cancer Institute and Little stars children hospital, ...
5
French “real life” experience of clofarabine in children with refractory or relapsed acute lymphoblastic leukaemia
... Acute lymphoblastic leukaemia (ALL) is the most com- mon form of cancer in children, responsible for approxi- mately 30 percent of all childhood ...
8
A causal mechanism for childhood acute lymphoblastic leukaemia.
... In this Review, I present evidence supporting a multi-factorial causation of childhood acute lymphoblastic leukaemia (ALL), a major subtype of paediatric cancer. ALL evolves in two discrete steps. ...
44
Determination of the DNA repair pathways utilised by acute lymphoblastic leukaemia cells following daunorubicin treatment
... Factors influencing choice between NHEJ and HR are still unclear as many factors influence these processes including MRN complex, cell cycle checkpoints, and DNA-DSB effector proteins [14]. The aim of this study was to ...
5
Third-generation CD28/4-1BB chimeric antigen receptor T cells for chemotherapy relapsed or refractory acute lymphoblastic leukaemia: a non-randomised, open-label phase I trial protocol
... Introduction: There is no curative treatment available for patients with chemotherapy relapsed or refractory CD19+ B cells-derived acute lymphoblastic leukaemia (r/r B-ALL). Although CD19-targeting ...
7
Effect of dexamethasone on quality of life in children with acute lymphoblastic leukaemia: a prospective observational study
... Acute Lymphoblastic Leukaemia (ALL) is the most com- mon form of childhood cancer. Over the past decades sur- vival following treatment for childhood ALL has improved substantially, now reaching ...
8
The Role of MicroRNA in Paediatric Acute Lymphoblastic Leukaemia: Challenges for Diagnosis and Therapy.
... Acute lymphoblastic leukaemia (ALL) is the most common cancer of ...90%, leukaemia remains one of the leading causes of death from ...childhood leukaemia, focussing primarily on their ...
15
Longitudinal assessment of nutritional status and its effects on the outcome of children completed treatment for Acute Lymphoblastic Leukaemia.
... Acute Lymphoblastic Leukaemia (ALL) is the most common cancer in children and it accounts for 25% of all childhood malignancies 4 .Survival rates of ALL has improved dramatically since 1980. ...
152
The subclonal complexity of STIL-TAL1+ T-cell acute lymphoblastic leukaemia.
... detectable leukaemia subclone contained the STIL-TAL1 fusion and copy number loss of ...this leukaemia subtype, which con fi rmed that mutations in key T-ALL drivers, including NOTCH1 and PTEN, were ...
10
Osteonecrosis in patients with acute lymphoblastic leukaemia: a national questionnaire study
... Age and ethnicity were found to be the most significant risk factors for development of ON, with Asian patients and patients aged 10–20 years at diagnosis of ALL at greatest risk.. Th[r] ...
7
Cytogenetic and molecular aberrations in childhood B lineage acute lymphoblastic leukaemia
... Background: Acute Lymphoblastic Leukemia (ALL) is a common hematological malignancy in children and is characterized by genetic changes such as mutations and chromosomal ...
5
Understanding Acute Lymphoblastic Leukaemia
... It is best that you or your partner tell your children about your leukaemia diagnosis. If this is not possible, then someone else close to your children should break the news. How much you tell children will ...
41
Nutritional Assessment and Serum Zinc Level in Children with Acute Lymphoblastic Leukaemia
... indicates wasting among the older children. The high number of malnourished children at diagnosis in this study might be that most of the children in Dhaka Medical College Hospital come from low socioeconomic status and ...
5
Chromosome 6q16-21 deletions in acute lymphoblastic leukaemia
... In leukaemia lymphoma cell lines with MSI, frameshift mutations were most frequently detected in the BAX gene (82%), while the MSH3, MSH6, TGF-p type II receptor, IGF-IIR genes were less frequently mutated ...
234
Analysis of ZAP70 expression in adult acute lymphoblastic leukaemia by real time quantitative PCR
... adult acute lymphoblastic leukemia (ALL): analysis of cytogenetic data from patients treated on the Medical Research Council (MRC) UKALLXII/Eastern Cooperative Oncology Group (ECOG) 2993 ...
5