adenylate cyclase
Schizosaccharomyces pombe Git1 Is a C2-Domain Protein Required for Glucose Activation of Adenylate Cyclase
... and adenylate cyclase, we examined whether Git1 is required either for adenylate cyclase localization or for stability, but found no significant change in adenylate cyclase ...
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Bordetella pertussis adenylate cyclase toxin modulates innate and adaptive immune responses: distinct roles for acylation and enzymatic activity in immunomodulation and cell death
... Adenylate cyclase toxin (CyaA) of Bordetella pertussis belongs to the repeat in toxin family of pore-forming toxins, which require posttranslational acylation to lyse eukaryotic ...The adenylate ...
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The pituitary adenylate cyclase–activating polypeptide is a physiological inhibitor of platelet activation
... pituitary adenylate cyclase–activating polypeptide (PACAP) is a neuropeptide of the vasoactive intestinal peptide/secretin/glucagon ...peptide/pituitary adenylate cyclase–activating peptide ...
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Guanine nucleotide binding regulatory proteins and dual control of adenylate cyclase
... When the resolved subunits of G0 were tested for their ability to inhibit adenylate cyclase activity in platelet membranes, the inhibitory activity of the "activated" dimer was found to [r] ...
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Biphasic effects of prostaglandin E2 on the human fat cell adenylate cyclase
... Adenylate cyclase of human fat cell ghosts shows a biphasic response towards prostaglandin E2 with inhibition occurring at nanomolar concentrations of the hormone and stimulation at conc[r] ...
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Concanavalin A amplifies both beta adrenergic and muscarinic cholinergic receptor adenylate cyclase linked pathways in cardiac myocytes
... forskolin-stimulated adenylate cyclase activity in cell homogenates, suggesting that an intact cytoarchitecture is necessary for Con A to augment cAMP ...
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Decreased bioactivity of the guanine nucleotide binding protein that stimulates adenylate cyclase in hearts from cardiomyopathic Syrian hamsters
... cardiac adenylate cyclase in 29-d-old BIO ...of adenylate cyclase in cardiac membranes with isoproterenol, fluoride ion, guanine nucleotide, forskolin, and manganous ion indicated that there ...
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The Regulation of Skeletal Muscle Alanine and Glutamine Formation and Release in Experimental Chronic Uremia in the Rat: SUBSENSITIVITY OF ADENYLATE CYCLASE AND AMINO ACID RELEASE TO EPINEPHRINE AND SEROTONIN
... fluoride-stimulated adenylate cyclase activities were equal in uremic and control muscle homogenates and in membrane fractions, but 10 µM epinephrine-stimulated adenylate cyclase was reduced ...
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Responsiveness to glucagon in fetal hearts Species variability and apparent disparities between changes in beating, adenylate cyclase activation, and cyclic AMP concentration
... Previous studies of the ability of the immature heart to respond to glucagon have yielded conflicting results. To test the possibility that the apparent discrepancies might be explained in part by species variability, ...
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Adenylate cyclase toxin from Bordetella pertussis synergises with lipopolysaccharide to promote innate IL 10 production and enhance the induction of Th2 and regulatory T cells
... Adenylate Cyclase Toxin from Bordetella pertussis Synergizes with Lipopolysaccharide To Promote Innate Interleukin-10 Production and Enhances the Induction of Th2 and Regulatory T Cells [r] ...
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Original Article Role of adenylate cyclase-associated protein 1 in cancers
... Abstract: Cancer is a leading cause of death worldwide. Adenylate cyclase-associated protein 1 (CAP1) may play a role in cell motility and in the development of certain types of cancer. Here, we explore the ...
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Ventilatory and cardiovascular actions of centrally and peripherally administered trout pituitary adenylate cyclase activating polypeptide (PACAP) and vasoactive intestinal peptide (VIP) in the unanaesthetized trout
... Pituitary adenylate cyclase-activating polypeptide (PACAP) and vasoactive intestinal peptide (VIP) belong to the secretin–glucagon superfamily of peptides (Sherwood et ...
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Positive coupling of beta like adrenergic receptors with adenylate cyclase in the cnidarian Renilla koellikeri
... in adenylate cyclase activity of the cnidarian Chlorohydra viridissima following exposure to serotonin and dopamine, adenylate cyclase activity in the anthozoan ...of adenylate ...
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Deficient adenylate cyclase regulatory protein in renal membranes from a patient with pseudohypoparathyroidism
... Recent studies have established that some patients with pseudohypoparathyroidism have a deficiency of the adenylate cyclase regulatory protein (the G unit) in plasma membranes from erythrocytes, platelets, ...
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Functional Profile of the Isolated Uremic Nephron: IMPAIRED WATER PERMEABILITY AND ADENYLATE CYCLASE RESPONSIVENESS OF THE CORTICAL COLLECTING TUBULE TO VASOPRESSIN
... Resistance of the chronically diseased kidney to vasopressin has been proposed as a possible explanation for the urinary concentrating defect of uremia. The present studies examined the water permeability and ...
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Ectopic beta adrenergic receptor binding sites possible molecular basis of aberrant catecholamine responsiveness of an adrenocortical tumor adenylate cyclase
... the adenylate cyclase of adrenocortical carcinoma 494 was ...The adenylate cyclase of this corticosteroid-producing, transplanted, adrenal cancer of the rat was stimulated not only by ...
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Effects of vasopressin antagonist on vasopressin binding, adenylate cyclase activation, and water flux
... adenylate cyclase activation by AVP in cortical, medullary, and papillary collecting tubules and in the medullary thick ascending ...of adenylate cyclase by parathyroid hormone in the cortical ...
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Factors associated with humoral hypercalcemia of malignancy stimulate adenylate cyclase in osteoblastic cells
... of adenylate cyclase in ROS ...for adenylate cyclase ...of adenylate cyclase by HHM factors was inhibited by the parathyroid hormone competitive inhibitor, [8norleucyl, ...
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Effects of cholera toxin on adenylate cyclase Studies with guanylylimidodiphosphate
... on adenylate cyclase was ...liver adenylate cyclase by cholera toxin in vivo, or by cholera toxin and NAD in homogenates, blocked the stimulatory effect of ...
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Bordetella Adenylate Cyclase Toxin Inhibits Monocyte to Macrophage Transition and Dedifferentiates Human Alveolar Macrophages into Monocyte like Cells
... an adenylate cyclase toxin-hemolysin (CyaA) that binds my- eloid phagocytes through complement receptor 3 (CD11b/CD18) and swiftly delivers its adenylyl cyclase enzyme domain into ...
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