Adenylate kinase
Modulation of anti-cancer drug sensitivity through the regulation of mitochondrial activity by adenylate kinase 4
... Fig. 2 Decreased drug tolerance due to adenylate kinase 4 (AK4) knockdown in HeLa cells. a Left panel: western immunoblotting showing AK4 knockdown in cells expressing AK4 short hairpin (sh)RNA. AK4, 25 ...
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Adenylate kinase locus 1 genetic polymorphism and type 2 diabetes
... [3] Matsuura, S., Igarashi, M., Tanizawa, Y., Yamada, M., Kishi, F., Kajii, T., Fujii, H., Miwa, S., Sakurai, M. and Nakazawa, A. (1989) Human adenylate kinase deficiency associated with hemolytic anemia. A ...
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Plasmodium Rab5b is secreted to the cytoplasmic face of the tubovesicular network in infected red blood cells together with N acylated adenylate kinase 2
... Adenylate kinase 2 (PfAK2, PF08_0062) is an N-ter- minally myristoylated and palmitoylated protein that is transported to the PVN and TVN [12, 13]. PfAK2 does not possess a canonical PEXEL motif and N-ter- ...
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Adenylate kinase 4 modulates oxidative stress and stabilizes HIF-1α to drive lung adenocarcinoma metastasis
... Adenylate kinase 4 (AK4) is localized in the mitochon- drial matrix [8] and has been shown to physically bind to mitochondrial ADP/ATP translocase (ANT) as a stress-responsive protein to maintain cell ...
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The increase of adenylate kinase activity in the blood can control aggregation of platelets in coronary or peripheral arterial ischemia
... In the aggregation process induced by 20 μM ADP, concentration of the nucleotide is high enough for the activated platelets to partially undergo irreversible ag- gregation [30,31]. In this case, NTPDase1 as well as ...
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Adjustment of K' to varying pH and pMg for the creatine kinase, adenylate kinase and ATP hydrolysis equilibria permitting quantitative bioenergetic assessment
... creatine kinase (ATP: creatine N-phosphotransferase; EC 2.7.3.2), adenylate kinase (ATP:AMP phosphotransferase; EC 2.7.4.3) and adenosinetriphosphatase (ATP phosphohydrolase; EC 3.6.1.3) reactions. ...
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Metabolic compensation for profound erythrocyte adenylate kinase deficiency A hereditary enzyme defect without hemolytic anemia
... A child with hemolytic anemia was found to have severe erythrocyte adenylate kinase (AK) deficiency, but an equally enzyme-deficient sibling had no evidence of hemolysis. No residual enzyme activity was ...
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HUMAN FETAL GROWTH RETARDATION: III. PROTEIN, DNA, RNA, ADENINE NUCLEOTIDES AND ACTIVITIES OF THE ENZYMES PYRUVIC AND ADENYLATE KINASE IN PLACENTA
... in leukocytes, but also were significantly lower than in placental tissue of FT or IUM infants, in whose placentas the values were similar ( Fig. There was no correlation[r] ...
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Urinary adenylate kinase and urinary tract infections
... Other methods that distinguish between bladder and kidney infections include demonstration of decreased ability to concentrate urine 9, the finding of significant bacterial counts in cat[r] ...
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Human transposons are an abundant supply of transcription factor binding sites and promoter activities in breast cancer cell lines
... AK4: Adenylate kinase-4; ASP: Antisense promoter; BWA: Burrows-Wheeler Aligner; CAGE: Cap Analysis of Gene Expression; CHD: Chromodomain helicase DNA-binding protein; ChIP-seq: Chromatin[r] ...
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Phosphotransfer networks and cellular energetics
... creatine kinase or glycolytic reactions in one cellular locale could be rapidly transmitted through a near-equilibrium network in the form of a sharp concentration wavefront over macroscopic ...creatine ...
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Highly active engineered-enzyme oriented monolayers: formation, characterization and sensing applications
... In other words, can SAM chemistry mimic the natural environment of the protein? More open questions con- cern the conformational changes resulting from protein- surface interactions (post immobilization), and how they ...
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ATP regenerating system in the cilia of Paramecium caudatum
... arginine kinase activity has been reported for Tetrahymena pyriformis (Watts and Bannister, ...arginine kinase nor creatine kinase activity has been detected in the flagella of Chlamydomonas ...
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Genetic causes of male infertility: snapshot on morphological abnormalities of the sperm flagellum
... an adenylate kinase expressed in both cilia and sperm flagellum, was identified in two MMAF siblings ...Several adenylate kinases were re- ported as components of axonemal and peri-axonemal ...
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Thymosin beta 4 treatment improves left ventricular function after myocardial infarction and is related to Up-regulation of chitinase 3-like-1 in mice
... ADP: Adenosine diphosphate; ADPase: Collective name for ADP hydrolyzing enzymes; AK: Adenylate kinase; Akt: Protein kinase B; ATP: Adenosine triphosphate; ATPase: Collective name for ATP[r] ...
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Sequence-based prediction of permissive stretches for internal protein tagging and knockdown
... Adk: Adenylate kinase; ADP: Adenosine diphosphate; AMP: Adenosine monophosphate; ASA: Absolute surface area; aTc: Anhydrotetracycline; ATP: Adenosine triphosphate; Bla: β -lactamase; CFX: Cell-free extract; ...
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Serum biomarkers of delirium in the elderly: a narrative review
... “Adenylate kinase”, “Delir- ium” AND “Myokinase”, “Delirium” AND “Albumin”, “Delirium” AND “Amyloid”, “Delirium” AND “ASAT”, “Delirium” AND “Aspartate transaminase”, “Delirium” AND “Aspartate ...
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Multilocus enzyme analysis of Legionella dumoffii
... The following 20 enzymes were measured: esterase 2, esterase 3, esterase 5, esterase 6, isocitrate dehydrogenase, malate dehydrogenase, adenylate kinase, aconitase, phenylalanylleucine p[r] ...
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Bemeleit, Derk Julius (2008): Structural Characterization of the DNA Repair Protein Complex SbcC-SbcD of Thermotoga maritima. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... Rad50 in eukaryotes and archaea and SbcC in bacteria comprise one Walker A (yellow) and one Walker B (orange) motif carrying the ATPase activity, two heptad repeats folding into an antiparallel coiled-coil domain and a ...
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Effects of cholera toxin on adenylate cyclase Studies with guanylylimidodiphosphate
... of adenylate cyclase by maximal concentrations of Gpp(NH)p, but not by submaximal concentrations, blocked the stimulatory effect of cholera ...the adenylate cyclase ...
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