adipogenic differentiation
PPARγ agonist through the terminal differentiation phase is essential for adipogenic differentiation of fetal ovine preadipocytes
... adipogenesis, adipogenic differentiation, and their regulation, investigators often resource to the commercially available preadipocyte cell line 3T3-L1 of murine origin ...tissue differentiation and ...
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MicroRNA 138 Suppresses Adipogenic Differentiation in Human Adipose Tissue Derived Mesenchymal Stem Cells by Targeting Lipoprotein Lipase
... ogenic differentiation of hAMSCs, the cells were divided into four transfection groups: miR-NC mimics, miR-138 mimics, miR-138 mimics+pcDNA, and miR-138 ...of adipogenic transcription factors was detected ...
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<p>Muscone Promotes The Adipogenic Differentiation Of Human Gingival Mesenchymal Stem Cells By Inhibiting The Wnt/β-Catenin Signaling Pathway</p>
... the adipogenic differentiation of preadipocytes and accelerates the differentiation of adipocytes, 53,54 while activating the classical Wnt pathway promotes the osteogenesis of BMSCs by upregulating ...
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Zinc finger factor 521 enhances adipogenic differentiation of mouse multipotent cells and human bone marrow mesenchymal stem cells
... enhance adipogenic differentiation of human ...osteoblastic differentiation for 15 days, Alizarin Red S staining showed that ZNF521 knockdown increased differentiation activity by ...
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Adipocyte-derived stem cell-based gene therapy upon adipogenic differentiation on microcarriers attenuates type 1 diabetes in mice
... the adipogenic differentiation of ...competent differentiation efficiency, considering their epithelial origin, vigorous protein syn- thesis and secretion, and closer relationship to the pan- creatic ...
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PPARγ agonists enhance ET 743–induced adipogenic differentiation in a transgenic mouse model of myxoid round cell liposarcoma
... reflects adipogenic differentiation–mediated downregula- tion of the Prx1 promoter, we performed transcriptional run-on assays on single-cell suspensions of cells isolated from the tumors of mice treated as ...
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Effects of Human Insulin Gene Transfection on the Adipogenic Differentiation of Human Umbilical Cord Mesenchymal Stem Cells in Silk Fibroin Scaffolds in Vitro
... the differentiation and proliferation of the seed cells into adipocytes, a special microenvironment and some growth factors are needed to regulate the ability of directed differentiation ...the ...
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The roots of Atractylodes japonica Koidzumi promote adipogenic differentiation via activation of the insulin signaling pathway in 3T3 L1 cells
... The present study provides the first evidence that the root extract of A. japonica (ARA) promotes the insulin-induced conversion of preadipocytes into adi- pocytes, accompanied by increased expression of PPARγ, a key ...
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Dysregulated systemic lymphocytes affect the balance of osteogenic/adipogenic differentiation of bone mesenchymal stem cells after local irradiation
... osteogenic differentiation. Adipogenic differentiation was induced by culturing with insulin (10 mg/ml), dexamethasone (1 mM), and 3-isobutyl-1- methylxanthine ...
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Original Article Effects of amygdalin on alcohol-induced adipogenic differentiation of rabbit bone marrow mesenchymal stem cells
... the adipogenic differentiation and proliferation of pluripotent stem cells, and inhibit osteogenic differentiation, thus leading to reduction of bone ...adipocyte differentiation is closely ...
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The Power of LC-MS Based Multiomics: Exploring Adipogenic Differentiation of Human Mesenchymal Stem/Stromal Cells
... labeled compounds, hyphenated high-end mass spectrometry (high-resolution Orbitrap MS) and chromatography (HILIC, RP) for simultaneous untargeted screening and targeted quantification. Metabolite and lipid concentrations ...
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Effect of Osteoking on the osteogenic and adipogenic differentiation potential of rat bone marrow mesenchymal stem cells in vitro
... osteogenic differentiation compared to normal ...and adipogenic differentiation potential of rbMSCs in ...osteogenic differentiation and inhibit adipogenic differenti- ation of ...
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Downregulation of PPARγ by miR 548d 5p suppresses the adipogenic differentiation of human bone marrow mesenchymal stem cells and enhances their osteogenic potential
... promotes adipogenic differentiation [9], a complex pro- cess involving a coordinated cascade of multiple tran- scription factors and signaling ...the adipogenic genes that ultimately give rise to the ...
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HIF-1A and C/EBPs transcriptionally regulate adipogenic differentiation of bone marrow-derived MSCs in hypoxia
... The adipogenic differentiation of BMSCs under hypoxia can be considered as a molecular adaptation to help cancer cells survive the loss of vital mole- cules such as oxygen or ...the differentiation ...
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Ethyl acetate fraction of Huogu formula inhibits adipogenic differentiation of bone marrow stromal cells via the BMP and Wnt signaling pathways
... on adipogenic and osteogenic differentiation in rat primary BMSCs and in the steroid-induced ONFH ...inhibited adipogenic differentiation, but slightly promoted osteogenic ...
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Proliferation and adipogenic differentiation of human adipose-derived stem cells isolated from middle-aged patients with prominent orbital fat in the lower eyelids
... When OASCs of passage 3 from both young and middle-aged groups reached near-confluence, adipogenic differentiation was induced by replacing GM with the adipogenic medium (AM, consisting of GM plus ...
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Original Article miR-135a-5p affects adipogenic differentiation of human adipose-derived mesenchymal stem cellsby promoting the Hippo signaling pathway
... The primary reason for obesity is an imbalan- ce between energy intake and consumption. A variety of diseases are associated with obesi- ty, including hypertension, pathoglycemia, dys- lipidemia, and even heart disease ...
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miR-431 inhibits adipogenic differentiation of human bone marrow-derived mesenchymal stem cells via targeting insulin receptor substance 2
... during adipogenic differentiation of hMSCs, and since a miR-431 complementary site has been predicted in the 3 ′ -UTR of IRS2 [16], we speculated that IRS2 is a target of ...during adipogenic ...
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Taurine Transporter Regulates Adipogenic Differentiation of Human Adipose-Derived Stem Cells through Affecting Wnt/β-catenin Signaling Pathway
... adipocyte differentiation, we isolated hASCs from subcutaneous adipose tissues and performed transcriptome ...promoted adipogenic differentiation, whereas taurine and TauT knockdown impeded ...
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Original Article MiR-140-5p suppresses the adipogenic differentiation of mesenchymal stem cells in rats with steroid-induced osteonecrosis of the femoral head
... with adipogenic differentiation medium (Jiangsu Punuosheng Biotechnology ...inducing adipogenic differentia- tion, and ATRA, miR-NC, or siRNA-miR-140-5p were simultaneously ...to adipogenic ...
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