Adipose derived Mesenchymal Stem Cells
Vitamin D machinery and metabolism in porcine adipose-derived mesenchymal stem cells
... muscle cells, endothelial cells, and cardiomyocytes ...chymal stem cells (MSCs). MSCs are multipotent cells that have the capacity to self-renew and differentiate into different ...
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Multiomics global landscape of stemness-related gene clusters in adipose-derived mesenchymal stem cells
... that adipose-derived stromal vascular fractions (AD-SVFs) [1, 2] and adipose-derived stem cells (ASCs) [3, 4] can enhance tissue regeneration potential ...heterogeneous ...
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Intratracheal administration of adipose derived mesenchymal stem cells alleviates chronic asthma in a mouse model
... Mesenchymal stem cells (MSCs), pluripotent cells derived from early mesoderm, can differentiate into fat, bone, cartilage, epithelial cells and endothelial cells ...
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Original Article Culture and properties of adipose-derived mesenchymal stem cells: characteristics in vitro and immunosuppression in vivo
... of adipose and bone marrow derived mesenchymal stem cells (BM- SCs and AMSCs) in immune regulation and to evaluate the therapeutic effects of AMSCs on Con A induced hepatitis and the ...
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Adipose-derived mesenchymal stem cells from liposuction and resected fat are feasible sources for regenerative medicine
... As adipose-derived mesenchymal stem cells (AMSCs) are a very promising approach for the future and they can be obtained from different sources, there is a need to compare the different ...
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Adipose derived mesenchymal stem cells markedly attenuate brain infarct size and improve neurological function in rats
... while stem cell therapy, including bone marrow-derived mesenchymal stem cells [15-17], embry- onic stem cells [14] and endothelial progenitor cells [18], have been ...
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Mechanisms utilized by feline adipose-derived mesenchymal stem cells to inhibit T lymphocyte proliferation
... Feline adipose-derived mesenchymal stem cells (ASCs) Low passage (P1–P5) adipose-derived feline mesenchymal stem cells (ASCs) were isolated from ...
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The Role of Adipose Derived Mesenchymal Stem Cells in Enhancement of Peripheral Nerve Injuries Repair
... from adipose tissue, peripheral blood, lungs and heart(24). Adipose-derived mesenchymal stem cells (ADSCs) express phenotypic and gene expression profiles similar to bone marrow ...
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Human and feline adipose-derived mesenchymal stem cells have comparable phenotype, immunomodulatory functions, and transcriptome
... Fig. 6 Transcriptome analysis reveals similarities between human and feline adipose-derived mesenchymal stem cells ( ASCs ) at the molecular level. Total RNA was isolated from ...
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In-vitro labelling of ovine adipose-derived mesenchymal stem cells (oADMSCS) and tracking using MRI technique
... successful stem cell-based therapy, the monitoring of transplanted cell’s migration, homing as well as the engraftment efficiency and functional capability in-vivo has become a critical ...of cells was ...
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Transdifferentiation of human adipose-derived mesenchymal stem cells into oligodendrocyte progenitor cells
... condition at 4 °C overnight. For this purpose, anti- A2B5 FITC antibody (1 µg/ml Abcam, Cambridge, MA, USA), anti-oligodendrocyte transcription factor (Olig2) FITC antibody (1:1000; Abcam, Cambridge, MA, USA), anti- ...
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Regulation of somatostatin expression by vitamin D3 and valproic acid in human adipose-derived mesenchymal stem cells
... Fig. 5 Effect of valproic acid (VPA) on somatostatin (SST) production and secretion of ADMSC. a SST mRNA expression was increased 3.6 ± 0.3 fold by 1 mM VPA after 5 days of culture compared to the absence of VPA ( n = 5, ...
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Distinct features of rabbit and human adipose-derived mesenchymal stem cells: implications for biotechnology and translational research
... This study highlighted the distinct features of rASCs and hASCs and their possible implications to biotechnology applications and translational studies (Table 3). Both ASCs presented differentiation potential to ...
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Comparison of senescence-related changes between three- and two-dimensional cultured adipose-derived mesenchymal stem cells
... of stem cell properties ...these cells were morphologically younger when compared with 2D culture cells, at the same time period; and more importantly, SA-β-gal ex- pression in these cells ...
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Adipose-derived mesenchymal stem cells improve glucose homeostasis in high-fat diet-induced obese mice
... Methods: Seven-week-old C57BL/6 mice were fed a high-fat diet for 20 weeks to generate the DIO mouse model. Mice were given a single intravenous infusion of ex vivo expanded syngeneic ASCs at 2 × 10 6 cells per ...
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Adipose-derived mesenchymal stem cells attenuate acute lung injury and improve the gut microbiota in septic rats
... In recent years, ADMSCs have been used as a new treat- ment strategy for diseases related to inflammation and tis- sue damage [12–15]. MSCs are easy to obtain and possess immunomodulatory therapeutic properties and ...
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ERK signaling is required for VEGF-A/VEGFR2-induced differentiation of porcine adipose-derived mesenchymal stem cells into endothelial cells
... hematopoietic stem cell marker CD45 and macrophage marker CD11b. Cells were de- tached from the monolayer with ...The cells were washed three times in PBS, and resuspended in 500 μl ...
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Human adipose-derived mesenchymal stem cells alleviate obliterative bronchiolitis in a murine model via IDO
... The cells were treated with trypsin/EDTA and replated at a density of 4000 cells/cm 2 when the cultures were close to confluence ...ASCs, cells were cultured with osteogenic medium containing 10% ...
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Histone demethylase JMJD6 regulates cellular migration and proliferation in adipose-derived mesenchymal stem cells
... differentiation [51, 52]. Cellular maintenance of an ap- propriate level of cAMP and cGMP is critical. For ex- ample, increasing the intracellular cAMP levels can lead to cardiomyocyte differentiation and inhibition of ...
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Applicability of adipose-derived mesenchymal stem cells in treatment of patients with type 2 diabetes
... into cells expressing insulin in a glucose-dependent ...vitro, cells were transplanted into a T2DM mouse ...the cells can express insulin, which may not be sufficient to explain the regenerated β ...
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