Adipose tissue-derived stromal cells
Human cord blood-derived platelet lysate enhances the therapeutic activity of adipose-derived mesenchymal stromal cells isolated from Crohn’s disease patients in a mouse model of colitis
... Mesenchymal stromal cells (MSCs) are multipotent adult stem cells [1] which can differentiate in vitro and in vivo into several tissue lineages originating from the three ger- minal layers [2, ...
16
Current use of autologous adipose tissue-derived stromal vascular fraction cells for orthopedic applications
... The adipose SVF contains numerous cells types, including red blood cells (RBCs), white blood cells (WBCs), adipocytes, along with MSCs [8, ...the adipose SVF may contain left-over ...
12
Therapeutic effects of adipose-tissue-derived mesenchymal stromal cells and their extracellular vesicles in experimental silicosis
... million cells were characterized as MSCs through flow cytometry and induction of differentiation into osteoblasts and chon- droblasts as previously described ...[26]. Cells from the third to fifth passage ...
10
The effect of culture media on large-scale expansion and characteristic of adipose tissue-derived mesenchymal stromal cells
... expanding cells for clinical use ...animal- derived serum may lead to the introduction of xenogen- eic antigens with MSC transplant and host immune re- jection [21–24], possible contamination with non- ...
11
Improved GMP compliant approach to manipulate lipoaspirates, to cryopreserve stromal vascular fraction, and to expand adipose stem cells in xeno-free media
... Adipose tissue, beside its role for energy storage, is a known source of stromal precursors and stem ...These cells are enclosed in the so-called stromal vascular fraction (SVF), a ...
16
Adipose tissue-derived stromal vascular fraction in regenerative medicine: a brief review on biology and translation
... SVF cells and ADSCs is also an evolving area and we look into unusual expression of CD34 antigen as an interesting marker for such ...different cells of the SVF, we draw a potential mode of action, ...
10
Syngenic Adipose-Derived Stem/Stromal Cells Delivered in Decellularized Adipose Tissue Scaffolds Enhance In Vivo Tissue Regeneration Through Host Cell Recruitment
... regenerative process. As mentioned, a major issue that has been encountered in the use of synthetic implants is the tendency for the material to become encapsulated in an almost avascular sheath of connective ...
151
Intra articular injection in the knee of adipose derived stromal cells (stromal vascular fraction) and platelet rich plasma for osteoarthritis
... stem cells (MSCs) have emerged as a can- didate cell type with great potential in regenerative medi- cine ...multiple tissue types and to self-renew [10, ...
11
Are mesenchymal stromal cells immune cells?
... non-haematopoietic cells may not be as sharp as commonly ...that adipose tissue-derived MSCs ex- press the haematopoietic stem cell marker ...stem cells in mice led to the generation of ...
7
The Co-Delivery of Syngeneic Adipose-Derived Stromal Cells and Macrophages on Decellularized Adipose Tissue Bioscaffolds for In Vivo Soft Tissue Regeneration
... unique, tissue- specific composition and material properties found in the native ECM 127 .... Tissue decellularization is an alternative option that utilizes a “top-down” fabrication strategy in which ...
135
Adipose tissue-derived mesenchymal stem cells and platelet-rich plasma: stem cell transplantation methods that enhance stemness
... progenitor cells with self-renewal properties and multi- potent differentiation profiles ...of stromal cells per gram and their differentiation capacity ...pose tissue and white adipose ...
7
Safety of adipose-derived cell (stromal vascular fraction – SVF) augmentation for surgical breast reconstruction in cancer patients
... stem cells are present in all the tissues of the human body as the cellular component of connective ...in tissue repair, an immunomodulatory role in suppressing immune reactions against own and transplanted ...
6
Effects of platelet-rich plasma on the activity of human menstrual blood-derived stromal cells in vitro
... transplanted cells used in stem cell-based therapies ...Adult cells, such as epithelial cells, chondro- cytes and osteoblasts as well as multipotent cells, such as adipose ...
11
Adipose-derived stromal cells in regulation of hematopoiesis
... and tissue selection, as well as the manner of isolation, expansion, preservation, and infusion of ...of cells (Table 2). ASCs from the subcutaneous and omental adipose tissue depot showed ...
11
Inflammatory priming enhances mesenchymal stromal cell secretome potential as a clinical product for regenerative medicine approaches through secreted factors and EV-miRNAs: the example of joint disease
... mesenchymal stromal cell (MSC)-based products have gained marketing approval by the regula- tory authorities [1] and mainly rely on MSCs derived from bone marrow (BMMSCs), adipose tissue ...
19
Altered protein secretions during interactions between adipose tissue- or bone marrow-derived stromal cells and inflammatory cells
... ST2 cells inhibited excessive se- cretion of MMP-9 and MMP-13 from neutrophils but caused excessive secretion of MMP-9 and MMP-13 in the presence of macrophages (Figure ...
10
Placenta-derived multipotent mesenchymal stromal cells: a promising potential cell-based therapy for canine inflammatory brain disease
... Adipose tissue-derived mesenchymal stromal cells (ASCs) Canine low passage (P2-P5) ASCs from 5 dogs were ob- tained from falciform fat collected from UCD William ...Briefly, ...
12
The ratio of ADSCs to HSC-progenitors in adipose tissue derived SVF may provide the key to predict the outcome of stem-cell therapy
... surrounding cells and orchestrate several biological processes ...healing cells can be made more bio-available by isolating them and re-introducing them in large num- bers into or near damaged ...
20
Autologous adipose-derived stromal vascular fraction and scarred vocal folds: first clinical case report
... of adipose tissue was performed with a 10 mL syr- inge in a closed circuit using a 3 mm Khouri cannula and a 500 mL collection bag; 340 ml of lipoaspirate was col- lected, transported to our registered Cell ...
6
Mesenchymal stromal cells: a novel therapy for the treatment of chronic obstructive pulmonary disease?
... Following this initial encouraging observation, several studies have investigated in vivo effects of MSCs in experimental models of COPD and emphysema, mainly in rats and mice. A variety of protocols was used to induce ...
10