adverse event
A pipeline to extract drug-adverse event pairs from multiple data sources
... from adverse event databases, enhanced by potential drug-adverse event pairs mined from non-traditional sources such as text from MEDLINE abstracts and user- comments from health-related ...
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A statistical analysis of vaccine-adverse event data
... are adverse, while some are not considered to be adverse, such as drug ineffective, inappropriate schedule of drug administration, unevaluable event, wrong drug administration, full blood count, full ...
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Recognizing Hypoglycemia in Children Through Automated Adverse-Event Detection
... There are some important limitations to our study. When the investigator was unable to confirm a false-positive trigger because of lack of confirma- tory testing, we deferred to the clini- cian’s determination and did not ...
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New dosing schedules of dasatinib for CML and adverse event management
... Patients should be monitored closely for the signs and symptoms of fluid retention, such as pitting edema, short- ness of breath, and rapid weight gain. Patients exhibiting these symptoms should undergo radiographic ...
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Adverse Event Following Immunization and its Management in Pediatric Population
... Vaccine Adverse Event Reporting System (VAERS) --- United States, 1991—2001During 1991--2001, VAERS received 128 717 reports, whereas >1,9 billion net doses of human vaccines were ...reported ...
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Pneumothorax as adverse event in patients with lung metastases of soft tissue sarcoma treated with pazopanib: a single reference centre case series
... Discussion: The incidence reported by us is higher than the incidence in the PALETTE study. Trials with pazopanib in renal cell carcinoma, urothelial carcinoma and cervix carcinoma did not report pneumothorax as an ...
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A signal detection method for temporal variation of adverse effect with vaccine adverse event reporting system data
... The adverse effect (AE) of a medication is a broad term referring to unwanted, uncomfortable, or dangerous ef- fects that a medication may have ...of adverse event reports in association with drugs/ ...
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Adverse event detection by integrating twitter data and VAERS
... Serious adverse reactions may even lead to ...Vaccine Adverse Event Report- ing System (VAERS) since 1990, which currently contains more than 500,000 reports in ...
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Hyperglycemic adverse events following antipsychotic drug administration in spontaneous adverse event reports
... specific adverse event versus all other adverse events for a given drug (antipsychotics), compared to the reporting odds for all other drugs present in the ...
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<p>Comparison of Adverse Event Profiles of Tumor Necrosis Factor-Alfa Inhibitors: Analysis of a Spontaneous Reporting Database</p>
... (DRUG), adverse events (REAC), and medical ...to adverse events was classi fi ed into three cate- gories: “ suspected medicine, ” “ concomitant medicine, ” and “ ...and adverse events in the “ ...
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Drug induced liver injury associated with Complementary and Alternative Medicine: a review of adverse event reports in an Asian community from 2009 to 2014
... The distribution of the type of hepatotoxicity reported is shown in Table 4. Majority (59.6 %) of the cases reported acute hepatitis as the main adverse event. Cholestatic hepatitis, on the other hand, was ...
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<p>Opioids and frequency counts in the US Food and Drug Administration Adverse Event Reporting System (FAERS) database: a quantitative view of the epidemic</p>
... Not surprisingly, the results of this study show that the proportion of deaths to opioid type to be highest with heroin, which validates the numerous news stories on opioid cause of death. Interestingly, the proportion ...
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Pirfenidone safety and adverse event management in idiopathic pulmonary fibrosis
... This safety and tolerability profile of pirfenidone observed in these large, randomised clinical trials has been supported by extensive real-world data and post-marketing experiences. The patient populations in these ...
10
OAE: The Ontology of Adverse Events
... of Adverse Events (OAE), previously named Adverse Event Ontology (AEO), is a community-driven ontology developed to standardize and integrate data relating to AEs arising subsequent to medical ...
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TSCQ study: a randomized, controlled, open label trial of daily trimethoprim sulfamethoxazole or weekly chloroquine among adults on antiretroviral therapy in Malawi: study protocol for a randomized controlled trial
... AE, adverse event; ALT, alanine aminotransferase; ART, antiretroviral therapy; CBC, complete blood count; CI, confidence interval; COMREC, College of Medicine Research Ethics Committee; CQ, chloroquine; ...
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Adults with repaired tetralogy: low mortality but high morbidity up to middle age
... On the most recent visit, 156 (94%) patients were in sinus rhythm (see online supplementary table 2). Twenty-nine (17%) patients had at least one episode of an atrial arrhythmia. Atrial flutter (eight patients) was the ...
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Labeling an Adverse Drug Event “Preventable”
... This case also raises at least two critical questions about the patient-physician relationship and the appropriate response to a preventable adverse event: what is the extent of Dr. McKinley’s duty to Mr. ...
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Expert consensus and recommendations on safety criteria for active mobilization of mechanically ventilated critically ill adults
... an adverse event, or consequences of an adverse event, was high, yellow would indicate that mobilization was possible, but only after further consider- ation and/or further discussion among ...
9
Extracting Adverse Drug Event Information with Minimal Engineering
... Adverse drug events (ADEs) describe undesirable signs and symptoms that occur consequent to ad- ministration of a medication. ADEs may be iden- tified in randomized controlled trials (RCTs), ob- servational ...
6
Rationale, design, and baseline characteristics of a randomized, placebo-controlled cardiovascular outcome trial of empagliflozin (EMPA-REG OUTCOME™)
... major adverse cardiovascular events; 4P-MACE: 4-point major adverse cardiovascular events; ACR: Albumin/creatinine ratio; AE: Adverse event; AESI: Adverse events of special interest; ...
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