• No results found

aerobic glycolysis

FLIPL is critical for aerobic glycolysis in hepatocellular carcinoma

FLIPL is critical for aerobic glycolysis in hepatocellular carcinoma

... cell aerobic glycolysis could not only ad- vance the knowledge of the regulation of glucose metabol- ism in cancer cells but also provide new approaches for cancer ...affect aerobic ...

11

Therapeutic targeting of YY1/MZF1 axis by MZF1-uPEP inhibits aerobic glycolysis and neuroblastoma progression

Therapeutic targeting of YY1/MZF1 axis by MZF1-uPEP inhibits aerobic glycolysis and neuroblastoma progression

... Aerobic glycolysis facilitates malignant cell transformation, tumor initiation and aggressive progression [5], while inhibition of glycolysis impairs growth and metastasis of many tumor cells [10, ...

17

Separation of metabolic supply and demand: aerobic glycolysis as a normal physiological response to fluctuating energetic demands in the membrane

Separation of metabolic supply and demand: aerobic glycolysis as a normal physiological response to fluctuating energetic demands in the membrane

... In 1867 Pasteur demonstrated that yeast decrease ethanol production following aeration of the culture media [1]. This observation has led to an enduring paradigm that in the absence of pathology, glucose metabolism is ...

9

Decreased expression of GRIM-19 by DNA hypermethylation promotes aerobic glycolysis and cell proliferation in head and neck squamous cell carcinoma

Decreased expression of GRIM-19 by DNA hypermethylation promotes aerobic glycolysis and cell proliferation in head and neck squamous cell carcinoma

... Because GRIM-19 is critical for the function of the electron transport chain and oxidative phosphorylation in mitochondria, we next examined the effect of ectopic GRIM-19 expression on oxygen consumption in JHU-028 ...

15

Inhibition of hexokinase-2 with targeted liposomal 3-bromopyruvate in an ovarian tumor spheroid model of aerobic glycolysis

Inhibition of hexokinase-2 with targeted liposomal 3-bromopyruvate in an ovarian tumor spheroid model of aerobic glycolysis

... tumor aerobic glycolysis, and the biological assays used, such as hexokinase, and cytotoxic- ity together confirm the enhanced potency of 3-BPA when delivered in liposomal ...

19

LINK-A promotes cell proliferation through the regulation of aerobic glycolysis in non-small-cell lung cancer

LINK-A promotes cell proliferation through the regulation of aerobic glycolysis in non-small-cell lung cancer

... the aerobic glycolysis in NSCLC cells (Figure ...in aerobic glycolysis, 3-BrPA (50 µ M, an HK inhibitor) and specific siRNA were used to reduce HKII expression and activity in NCI- H1299 cells ...

10

Lactic acidosis switches cancer cells from aerobic glycolysis back to dominant oxidative phosphorylation

Lactic acidosis switches cancer cells from aerobic glycolysis back to dominant oxidative phosphorylation

... to aerobic glycolysis, it is interesting to ask if cancer cells can revert from Warburg effect to ...from glycolysis and OXPHOS is quantitatively ...from glycolysis and OXPHOS in 9 randomly ...

9

Sinomenine Inhibits Non-Small Cell Lung Cancer via Downregulation of Hexokinases II-Mediated Aerobic Glycolysis

<p>Sinomenine Inhibits Non-Small Cell Lung Cancer via Downregulation of Hexokinases II-Mediated Aerobic Glycolysis</p>

... via glycolysis even in the presence of ...of glycolysis and irreversibly phosphorylate glucose to ...the aerobic glycolysis in tumor cells and suppresses apoptosis by localizing in ...

13

Linkage of aerobic glycolysis to sodium potassium transport in rat skeletal muscle  Implications for increased muscle lactate production in sepsis

Linkage of aerobic glycolysis to sodium potassium transport in rat skeletal muscle Implications for increased muscle lactate production in sepsis

... between aerobic glycolysis and sodium– potassium transport has been demonstrated in diaphragm, vascular smooth muscle, and other cells, it is not known whether this linkage occurs in skeletal muscle ...

11

NEK2 Promotes Aerobic Glycolysis in Multiple Myeloma Through Regulating Splicing of Pyruvate Kinase

NEK2 Promotes Aerobic Glycolysis in Multiple Myeloma Through Regulating Splicing of Pyruvate Kinase

... on glycolysis to generate the energy needed for cellular processes rather than mitochondrial respiration despite of oxygen avail- able ...regulating aerobic glycolysis resulting in MM cell ...

11

CircPOSTN/miR-361-5p/TPX2 axis regulates cell growth, apoptosis and aerobic glycolysis in glioma cells

CircPOSTN/miR-361-5p/TPX2 axis regulates cell growth, apoptosis and aerobic glycolysis in glioma cells

... of lactate production and glucose consumption in the culture medium, and intracellular ATP, revealing glu- cose metabolism was declined, which were prominently reversed by miR-361-5p knockdown (Fig. 5a–f). We also ...

15

Chibby suppresses aerobic glycolysis and proliferation of nasopharyngeal carcinoma via the Wnt/β-catenin-Lin28/let7-PDK1 cascade

Chibby suppresses aerobic glycolysis and proliferation of nasopharyngeal carcinoma via the Wnt/β-catenin-Lin28/let7-PDK1 cascade

... suppresses aerobic glycolysis and the proliferation of nasopharyngeal carcinoma and that the Wnt/β-catenin- Lin28/let7-PDK1 cascade mediates this ...obic glycolysis in cancer, which highlights the ...

11

Dihydroartemisinin Inhibits the Proliferation of Leukemia Cells K562 by Suppressing PKM2 and GLUT1 Mediated Aerobic Glycolysis

<p>Dihydroartemisinin Inhibits the Proliferation of Leukemia Cells K562 by Suppressing PKM2 and GLUT1 Mediated Aerobic Glycolysis</p>

... high glycolysis rate in tumor cells is due to the up- regulation of enzymes in glycolysis, for example, hexoki- nase 2 (HK2), 6-phosphofructo-1-kinase (PFK1), pyruvate kinase (PK), and so ...in ...

10

By reducing hexokinase 2, resveratrol induces apoptosis in HCC cells addicted to aerobic glycolysis and inhibits tumor growth in mice

By reducing hexokinase 2, resveratrol induces apoptosis in HCC cells addicted to aerobic glycolysis and inhibits tumor growth in mice

... via glycolysis inhibition in aerobic glycolytic HCC cells ...the aerobic glycolysis contributes to sorafenib-resistance in HCC cells, and resistance can be overcome by inhibiting tumor ...

15

STK25-induced inhibition of aerobic glycolysis via GOLPH3-mTOR pathway suppresses cell proliferation in colorectal cancer

STK25-induced inhibition of aerobic glycolysis via GOLPH3-mTOR pathway suppresses cell proliferation in colorectal cancer

... Methods: The influences of STK25 on the cell proliferation were evaluated by MTT and colony formation assays. The roles of STK25 in aerobic glycolysis were determined by glucose uptake and lactate ...

14

Human lung fibroblast-to-myofibroblast transformation is not driven by an LDH5-dependent metabolic shift towards aerobic glycolysis

Human lung fibroblast-to-myofibroblast transformation is not driven by an LDH5-dependent metabolic shift towards aerobic glycolysis

... between aerobic glycolysis and myofibroblast differentiation in human lung fibroblasts using the LDH5 inhibitor Compound ...towards aerobic glycolysis upon TGF-β1 stimulation but has no effect ...

10

LncRNA MAFG-AS1 Accelerates Cell Migration, Invasion and Aerobic Glycolysis of Esophageal Squamous Cell Carcinoma Cells via miR-765/PDX1 Axis

<p>LncRNA MAFG-AS1 Accelerates Cell Migration, Invasion and Aerobic Glycolysis of Esophageal Squamous Cell Carcinoma Cells via miR-765/PDX1 Axis</p>

... In short, the researches on the role of lncRNAs in ESCC and how lncRNAs modulate the occurrence and development of ESCC are still in their preliminary stages. The current study examined the expression of a novel lncRNA ...

14

Tumor-secreted dickkopf2 accelerates aerobic glycolysis and promotes angiogenesis in colorectal cancer

Tumor-secreted dickkopf2 accelerates aerobic glycolysis and promotes angiogenesis in colorectal cancer

... Results: DKK2 could stimulate angiogenesis via accelerating the aerobic glycolysis of CRC cells, through which lactate is produced from glucose and accumulated in tumor microenvironment. Lactate functions ...

14

PRMT5 Promotes Aerobic Glycolysis and Invasion of Breast Cancer Cells by Regulating the LXR&alpha;/NF-&kappa;Bp65 Pathway

<p>PRMT5 Promotes Aerobic Glycolysis and Invasion of Breast Cancer Cells by Regulating the LXR&alpha;/NF-&kappa;Bp65 Pathway</p>

... of aerobic glycolysis is considered as one of the tumor mar- kers, and in BC, aerobic glycolysis can not only provide nutrition for cell proliferation but also help to promote cell ...

11

Disruption of the EZH2/miRNA/β-catenin signaling suppresses aerobic glycolysis in glioma

Disruption of the EZH2/miRNA/β-catenin signaling suppresses aerobic glycolysis in glioma

... of glycolysis despite the presence of ample oxygen, a phenomenon termed the Warburg effect (aerobic ...the glycolysis under basal conditions, the glycolytic capacity and the glycolytic ...

9

Show all 1207 documents...

Related subjects