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African Ancestry

Association of the BANK1 R61H variant with systemic lupus erythematosus in Americans of European and African ancestry

Association of the <em>BANK1</em> R61H variant with systemic lupus erythematosus in Americans of European and African ancestry

... As the association we observe is indeed of a very similar magnitude to that of the original report, this independent replication confi rms BANK1 as a genuine SLE susceptibil- ity gene; in addition we have extended this ...

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African ancestry and higher prevalence of triple negative breast cancer

African ancestry and higher prevalence of triple negative breast cancer

... that African ancestry might be associated with hereditary predisposition for high-risk breast cancer of a specific ...with African ancestry, therefore, has the potential for lead- ing to the ...

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Genetics of stroke in a UK African ancestry case-control study

Genetics of stroke in a UK African ancestry case-control study

... in African ancestry popu- lations. As studies in African ancestry populations grow larger, more SNPs will be identified, and this will no doubt influence the results from an equivalent ...

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African ancestry is associated with cluster-based childhood asthma subphenotypes

African ancestry is associated with cluster-based childhood asthma subphenotypes

... 103 African American individuals, respectively. Global African ances- try proportion varies from ...global African ancestry was associated with AD (mean ± SD of African origin is ...of ...

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Two Novel Susceptibility Loci for Prostate Cancer in Men of African Ancestry.

Two Novel Susceptibility Loci for Prostate Cancer in Men of African Ancestry.

... of African ancestry that may contribute to their greater disease incidence, we combined genetic association results from the African Ancestry Prostate Cancer GWAS Consortium (AAPC; 4853 case ...

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African Ancestry and Its Correlation to Type 2 Diabetes in African Americans: A Genetic Admixture Analysis in Three U.S. Population Cohorts

African Ancestry and Its Correlation to Type 2 Diabetes in African Americans: A Genetic Admixture Analysis in Three U.S. Population Cohorts

... in African Americans, statistical power remains an important ...elevated African ancestry ...are ancestry informative between Europeans and West Africans but less power for weaker ...genetic ...

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Racial Differences in the Oral Microbiome: Data from Low-Income Populations of African Ancestry and European Ancestry

Racial Differences in the Oral Microbiome: Data from Low-Income Populations of African Ancestry and European Ancestry

... We also found 19 rare taxa that showed a significantly higher prevalence among AAs. Among them, four species, Porphyromonas gingivalis, Prevotella intermedia, Trepo- nema denticola, and Filifactor alocis, have been ...

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Prostatic compensation of the vitamin D axis in African American men

Prostatic compensation of the vitamin D axis in African American men

... West African ancestry in the AA ...West African ancestry and vitamin D synthesis depends on UV penetration of the skin; therefore, vitamin D status negatively correlates with West ...

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Genomic ancestry and the social pathways leading to major depression in adulthood: the mediating effect of socioeconomic position and discrimination

Genomic ancestry and the social pathways leading to major depression in adulthood: the mediating effect of socioeconomic position and discrimination

... and African slaves and conse- quently individuals of black or white skin color could have a considerable amount of African and European ...the African diaspora, receiving seven times more slaves than ...

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Association between MEG3/miR-181b polymorphisms and risk of ischemic stroke

Association between MEG3/miR-181b polymorphisms and risk of ischemic stroke

... ASW: African ancestry in Southwest USA; BDNF : Brain-derived neurotrophic factor; CEU: Utah residents with Northern and Western European ancestry from the CEPH collection; CHB: Han Chinese in ...

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Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging

Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging

... Methods—In the discovery sample we recruited 20,719 stroke/dementia-free adults from 13 population-based cohort studies within the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium, among which ...

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PubMedCentral-PMC4746331.pdf

PubMedCentral-PMC4746331.pdf

... Amerindian ancestry but rare or ab- sent among populations of European or African ...Amerindian ancestry after the peopling of the Americas 85 and persisted as a result of local evolu- tionary ...

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Amerindian (but not African or European) ancestry is significantly associated with diurnal preference within an admixed Brazilian population

Amerindian (but not African or European) ancestry is significantly associated with diurnal preference within an admixed Brazilian population

... genetic ancestry within the Baependi Heart Study cohort, a highly admixed Brazilian population based in a rural ...of ancestry, using the Admixture program, and MEQ from 1,453 ...of African) ...

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Towards a phenome-wide catalog of human clinical traits impacted by genetic ancestry

Towards a phenome-wide catalog of human clinical traits impacted by genetic ancestry

... genetic ancestry (percent European and African ancestry) and clinical variables measured in an African American population from BioVU, the Vanderbilt University biorepository linked to ...

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PubMedCentral-PMC5296276.pdf

PubMedCentral-PMC5296276.pdf

... Because African descent populations have lower LD, previous investigations have traditionally explored only the 250 kb flanking regions of identified variants, whereas in European descent populations, ...

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PubMedCentral-PMC5451114.pdf

PubMedCentral-PMC5451114.pdf

... and African ancestry were available for analysis of subcutaneous and visceral adipose tissue volumetric traits, up to 11,596 from 6 cohorts of European, African, Asian, and Hispanic ancestry ...

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PubMedCentral-PMC4771070.pdf

PubMedCentral-PMC4771070.pdf

... European ancestry (EA), with effect sizes ranging from ...of African ancestry, so an analysis of multiethnic samples has the potential to find novel genetic ...

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Differences in genomic abnormalities among African individuals with monoclonal gammopathies using calculated ancestry

Differences in genomic abnormalities among African individuals with monoclonal gammopathies using calculated ancestry

... genetic ancestry 15–17 . Lever- aging ancestry informative single-nucleotide polymorph- isms (SNPs) allows quantifying one ’ s genetic ancestry in an admixture ...genetic ancestry is a ...

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Genomic ancestry as a predictor of haemodynamic profile in heart failure

Genomic ancestry as a predictor of haemodynamic profile in heart failure

... of ancestry were normally distributed, except for the variable O/C ...Genetic ancestry variables were used as continuous vari- ...the African ancestry while the second model used the non-white ...

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Heterozygosity Ratio, a Robust Global Genomic Measure of Autozygosity and Its Association with Height and Disease Risk

Heterozygosity Ratio, a Robust Global Genomic Measure of Autozygosity and Its Association with Height and Disease Risk

... coded were downloaded for each individual in our data set. These ICD.9 codes were aggregated into PheWAS codes, us- ing the PheWAS package in R 3.2.0 (Carroll et al. 2014). An individual who had two or more ICD.9 codes ...

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