AIF, apoptosis inducing factor
Role of Apoptosis Inducing Factor (AIF) as Risk Factors of Premature Rupture of Membranes
... and apoptosis, and the stretch of the amniotic membrane. Apoptosis plays an integrated role in the pathogenesis of ...of apoptosis is through caspase-dependent and caspase-independent ...pathway. ...
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Apoptosis inducing factor (AIF) mediates lethal redox stress induced by menadione
... Mitochondrial apoptosis inducing factor (AIF) is a redox-active enzyme that participates to the biogenesis/maintenance of complex I of the respiratory chain, yet also contributes to catabolic ...
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The role of HGF-MET pathway and CCDC66 cirRNA expression in EGFR resistance and epithelial-to-mesenchymal transition of lung adenocarcinoma cells
... AIF: Apoptosis-inducing factor; ATAD3A: ATPase family, AAA domain-containing 3A; ATM: Ataxia-telangiectasia-mutated kinase; CCDC66: Coiled-coil domain containing 66; CIP: Calf intestinal ...
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Brain selective kinase (BRSK) interactions with tau as a cause of neurodegeneration
... Abbreviations and acronyms AA: Amino acid Aβ: β amyloid Ach: Acetylcholine AD: Alzheimer’s disease AIF: Apoptosis-inducing factor AMP: Adenosine monophosphate Arpc2: Actin-related protei[r] ...
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The role of death-associated protein 3 in apoptosis, anoikis and human cancer
... death; AIF: Apoptosis inducing factor; AKT/PKB: Protein kinase B; APAF1: Apoptotic protease activating factor 1; BAX: BCL2 associated X protein; BCL2: B-cell lymphoma 2 protein; BID: ...
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CD317 Promotes the survival of cancer cells through apoptosis-inducing factor
... to apoptosis, and importantly, this effect of CD317-silencing was only observed in serum-deprived cells, implying that gene interference targeting CD317 might be used as a combined approach for the antiangio- ...
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Ginsenoside compound K induces apoptosis in nasopharyngeal carcinoma cells via activation of apoptosis-inducing factor
... HK-1 cells were seeded on a glass coverslip at a density of 2 × 10 5 cells/well in a 6-well plate and incubated over- night. Cells were starved with 1% FBS medium for 24 h and then treated with or without CK for another ...
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AIF Downregulation and Its Interaction with STK3 in Renal Cell Carcinoma
... Apoptosis-inducing factor (AIF) was initially identified as a death effector involved in caspase-independent apoptosis pathway ...length AIF is synthesized in cytoplasm as a ...
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CHROMONE-3-ALDEHYDE DERIVATIVES IMPROVE MUSCLE FUNCTION BY SUPPRESSING THE FORMATION OF APOPTOSIS-INDUCING FACTOR
... To conduct a series of biochemical tests produced the preliminary preparation of the biomaterial: the citrate blood was centrifuged with obtaining a serum in the regime of 3500 RPM for 15 min. the Muscle tissue is ...
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Endonuclease G takes part in AIF-mediated caspase-independent apoptosis in Mycobacterium bovis-infected bovine macrophages
... caspase‑independent apoptosis in bovine macrophages with the possible participation of apoptosis inducing factor mitochondria associated 1 (AIFM1/AIF), a flavoprotein that functions as ...
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Heat shock pretreatment improves mesenchymal stem cell viability by heat shock proteins and autophagy to prevent cisplatin-induced granulosa cell apoptosis
... the apoptosis of Sca-1+ stem cells and myocardial fibrosis and the improvement of car- diac ...decreased apoptosis of HS-MSCs, which was con- sistent with the result of a previous study ...
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Vascular endothelial growth factor (VEGF) upregulates BCL 2 and inhibits apoptosis in human and murine mammary adenocarcinoma cells
... cell apoptosis (Holmgren et al, 1995) an effect that to date, has been attributed to blood vessel ...angiogenic factor VEGF inhibits radiation-induced tumour cell apoptosis and chemotherapy- induced ...
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Apoptosis-inducing and apoptosis-preventing functions of poliovirus.
... gered apoptosis was prevented even when the drug was present from the onset of infection) but does require virus protein synthesis and is invalidated under nonpermissive conditions (remarkably, nonpermissive ...
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Distinct intracellular signaling in Tumor Necrosis Factor-related Apoptosis-inducing Ligand- and CD95 Ligand-mediated apoptosis
... TRAIL-induced apoptosis is strongly dependent on the mitochondrial route, it has been shown that some effects of TRAIL are mediated by direct activation of caspase-3 by up- stream caspase-8 ...induce ...
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TRAIL gene 1595C/T polymorphisms contribute to the susceptibility and severity of intervertebral disc degeneration: a data synthesis
... The mechanisms involved in IDD are still unclear, and many internal and external causes may contribute to histopathological changes in intervertebral disc [19]. IDD is known to be a multifactorial disease, and genetic ...
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Surface modification of TPGS b (PCL ran PGA) nanoparticles with polyethyleneimine as a co delivery system of TRAIL and endostatin for cervical cancer gene therapy
... polyethyleneimine was applied to be a vector of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and endostatin for cervical cancer gene therapy. Firstly, a novel biodegradable ...
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Reconstruction of gene regulatory networks reveals chromatin remodelers and key transcription factors in tumorigenesis
... necrosis factor-related apoptosis-inducing ligand) sensitivity [16] (Additional file 2: Figure S2), we assessed the global gene expression in all three cell lines and the ratio of expression levels ...
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Kemter, Elisabeth (2005): Untersuchung transgener Tiermodelle für die Xenotransplantation. Dissertation, LMU München: Tierärztliche Fakultät
... Bei dem Caspase-abhängigen intrazellulären Signalweg, induziert durch TRAIL/TRAIL-Rezeptor- Interaktion, erfolgt über die Rekrutierung von zytoplasmatischen Proteinen an die Todesdomäne der Rezeptoren die Bildung des ...
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Osteoprotegerin rich tumor microenvironment: implications in breast cancer
... necrosis factor receptor; TRAIL: TNF related apoptosis inducing ligand; IBC: Inflammatory breast cancer; RANKL: receptor activator of nuclear factor (NFΚB) ligand; OCIF: osteoclastogenesis ...
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Combination of isoliquiritigenin and tumor necrosis factor-related apoptosis-inducing ligand induces apoptosis in colon cancer HT29 cells
... of apoptosis. Bcl-2 and Bcl-xL can block apoptosis induced by TRAIL [30, ...TRAIL-induced apoptosis, and a defi- ciency of BAX abrogates TRAIL-induced apoptosis ...enhances apoptosis ...
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