Albumin and Mice
Prevention of diabetic nephropathy in db/db mice with glycated albumin antagonists A novel treatment strategy
... glycated albumin induces abnormalities in cultured mesangial cells that resemble those characterizing the glomerular mesangium in diabetes, and monoclonal antibodies (A717) specific for Amadori-modified glycated ...
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Immunization of AGE-modified albumin inhibits diabetic nephropathy progression in diabetic mice
... Background: Diabetic nephropathy (DN) is a serious vascular complication of diabetes and an important cause of end-stage renal disease. One mechanism by which hyperglycemia causes nephropathy is through the formation of ...
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Proteinuria precedes podocyte abnormalities inLamb2–/– mice, implicating the glomerular basement membrane as an albumin barrier
... Primary defects in either podocytes or the glomerular basement membrane (GBM) cause proteinuria, a fact that complicates defining the barrier to albumin. Laminin b2 (LAMB2) is a GBM component required for proper ...
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Protective role of B cells in sterile particulate–induced lung injury
... BeO-exposed mice, we que- ried whether the MyD88 pathway was involved in the recruitment of B cells to the lungs of BeO-exposed ...STING-KO mice to BeO and analyzed the number of B cells in lung tissue at ...
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Albumin associated free fatty acids induce macropinocytosis in podocytes
... serum albumin stimulated macropinocytosis through a pathway that involves FFA receptors, the Gb/Gg complex, and ...Moreover, mice with elevated levels of plasma FFAs as the result of a high-fat diet were ...
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Hepatoprotective Effect of Sesame Oil against Lead Induced Liver Damage in Albino Mice: Histological and Biochemical Studies
... albino mice from the histological and biochemical ...albino mice were used for this study and divided into four ...and albumin were ...and albumin were ...
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In vivo hepatogenic capacity and therapeutic potential of stem cells from human exfoliated deciduous teeth in liver fibrosis in mice
... mice transplanted with SHED, Figure S8 showing human HLA-ABC, hepatocyte paraffin1 (Hep Par1), or human albumin (hALB) antibody-positive area in the recipient liver tissues of secondary [r] ...
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α1-antitrypsin promotes SPLUNC1-mediated lung defense against Pseudomonas aeruginosa infection in mice
... Western blot analysis was carried out to quantify SPLUNC1 protein. In brief, 30 μl BAL fluid was elec- trophoresed on 10% SDS-polyacrylamide gel electrophor- esis, transferred onto a nitrocellulose membrane, blocked with ...
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Regulation of iron homeostasis by the hypoxia inducible transcription factors (HIFs)
... with Albumin-Cre C57BL/6 transgenic mice. Deletion efficiency in total liver was approximately 70% as determined by quantita- tive PCR (data not shown). This indicates a very high rate of hepatocyte ...
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Investigations of the mechanisms of receptor-mediated immunoglobulin transport in mammals and birds
... While the involvement of FcRn in the serum maintenance of albumin has been experimentally demonstrated in mice, Chapter 2 describes that in vitro experiments using rat FcRn expressed in [r] ...
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Erythropoietin inhibits SGK1-dependent Th17 cell induction and Th17 cell–dependent kidney disease
... male mice (n = 3–4 per group) were treated with pristane at the age of 2 months and either EPO or vehicle control for 2 addi- tional months and then ...Urinary albumin/creat- inine ratio ...
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A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
... marrow–chimeric mice. (A–D) A2BAR bone marrow–chimeric mice were treated with BAY 60-6583 (2 mg/kg) 30 minutes prior to induction of ...and mice were ven- tilated using an inspiratory pressure of 45 ...
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Immune sensitization to methylene diphenyl diisocyanate (MDI) resulting from skin exposure: albumin as a carrier protein connecting skin exposure to subsequent respiratory responses
... exposed mice to identify immunologically-relevant protein targets for MDI conjugation and (antigenic) ...that albumin conjugates may be uniquely suited as antigens in ...
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Epigallocatechin gallate inhibits hepatitis B virus infection in human liver chimeric mice
... Hu-FRG mice whose livers were repopulated with hu- man ...human albumin level, with no significant difference between the two groups ...Hu-FRG mice with HBV during EGCG treatment ...
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Alterations in Albumin Metabolism after Serum and Albumin Infusions
... Summary Albumin distribution and metabolism were studied in 12 rabbits receiving pooled rabbit serum and in 6 rabbits, tolerant to human serum albumin, receiving pooled human serum album[r] ...
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1.9 Conflict Curlys Wife
... anybody, I get awful lonely.’’ This shows us that she has no female friends or any friends at all. She has no one to share her problems/thoughts with and this could make her feel isol[r] ...
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AGI-134: a fully synthetic α-Gal glycolipid that converts tumors into in situ autologous vaccines, induces anti-tumor immunity and is synergistic with an anti-PD-1 antibody in mouse melanoma models
... Due to the impracticality of developing a human thera- peutic from a crude biological extract, we explored the use of a fully synthetic α-Gal glycolipid-like molecule, AGI-134, which is a small molecule with a simple, ...
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Identification and characterization of Clonorchis sinensis cathepsin B proteases in the pathogenesis of clonorchiasis
... Proteases are ubiquitous in nature and most organisms. In addition to their housekeeping functions, proteases are involved in the digestion of host proteins such as fi- bronectin, collagen and albumin, to ...
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Bromocresol Dye-binding Methods Underestimate Serum Albumin Value in Patients Treated with High Dose of Penicillin G
... protein, albumin and potassium before the treatment with penicillin G between BCG and BCP groups, as shown in Table ...serum albumin levels measured by a modified BCP method during the treatment or after ...
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The Effects of Adrenocortical Hormones on Albumin Metabolism Studied with Albumin I131
... Blythe and co-workers 25 have also re- degradation increased 27 per cent while increase ported, in abstract form, an increased rate of al- in synthesis replaced 48 per cent of the albumi[r] ...
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