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Alcoholic steatohepatitis

The role of adipose tissue in the pathogenesis of non-alcoholic steatohepatitis

The role of adipose tissue in the pathogenesis of non-alcoholic steatohepatitis

... Obesity is a complex condition that occurs when there is abnormal or excessive accumulation of fat in the body. [1] The increased rise in obesity rates have been associated with augmented caloric intake, changes in diet ...

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Clinical, epidemiological, and laboratory analysis of patients with non alcoholic steatohepatitis

Clinical, epidemiological, and laboratory analysis of patients with non alcoholic steatohepatitis

... analyzed alcoholic steatohepatitis, all diagnosed histopathologically after performing liver ...the alcoholic steatohepatitis patients, ...0.03). alcoholic steatohepatitis are ...

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Comparative studies on cryptogenic chronic liver disease specially related to  non alcoholic steatohepatitis (nash)  verses other  known  causes of  liver diseases  with  features of  de compensation   A case control study

Comparative studies on cryptogenic chronic liver disease specially related to non alcoholic steatohepatitis (nash) verses other known causes of liver diseases with features of de compensation A case control study

... nonalcoholic steatohepatitis (Turkiye Klinikleri, 2003; Khanna and Kumar, ...Nonalcoholic steatohepatitis (NASH) is the term used to describe the distinct clinical entity in which patients lack a history of ...

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Effects of Aerobic Exercise on the Intramuscular Lipid and Glycogen Content of Fiber Types in Soleus Muscles of Non Alcoholic Steatohepatitis Model Rats

Effects of Aerobic Exercise on the Intramuscular Lipid and Glycogen Content of Fiber Types in Soleus Muscles of Non Alcoholic Steatohepatitis Model Rats

... Nonalcoholic fatty liver disease (NAFLD) was characterized as a cause of potentially progressive liver damage, and was associated with metabolic disease. A severe form with features of fibrosis was defined as ...

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Olmesartan for non alcoholic steatohepatitis complicated with hypertension: An open label study

Olmesartan for non alcoholic steatohepatitis complicated with hypertension: An open label study

... Aim: We evaluated the long-term effects of olmesar- tan, an angiotensin type 1 receptor blocker, in pa- tients with non-alcoholic steatohepatitis (NASH) com- plicated with hypertension. Methods: All ...

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Methionine and Choline Deficient Diet-induced Non-Alcoholic Steatohepatitis in Rats: Role of Melatonin

Methionine and Choline Deficient Diet-induced Non-Alcoholic Steatohepatitis in Rats: Role of Melatonin

... Material and Methods: To achieve this aim, rats were fed MCD diet for 8 weeks to induce non-alcoholic steatohepatitis. Oral administration of MLN (10 mg/kg/day) was done for the last two consecutive weeks. ...

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Hepatocellular carcinoma and non-alcoholic steatohepatitis: the state of play

Hepatocellular carcinoma and non-alcoholic steatohepatitis: the state of play

... Hepatocellular carcinoma (HCC) is now the fifth cancer of greatest frequency and the second leading cause of cancer related deaths worldwide. Chief amongst the risks of HCC are hepatitis B and C infection, aflatoxin B1 ...

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The FLS (Fatty liver Shionogi) mouse reveals local expressions of lipocalin-2, CXCL1 and CXCL9 in the liver with non-alcoholic steatohepatitis

The FLS (Fatty liver Shionogi) mouse reveals local expressions of lipocalin-2, CXCL1 and CXCL9 in the liver with non-alcoholic steatohepatitis

... neutrophil count in the liver of patients with alcoholic hepatitis [37]. In addition, neutrophilic infiltration of liver tissue is known to cause insulin resistance in the liver [38]. In the present study, CXCL1 ...

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The role of Ursodeoxycholic acid in non-alcoholic steatohepatitis: a systematic review

The role of Ursodeoxycholic acid in non-alcoholic steatohepatitis: a systematic review

... Ursodeoxycholic acid (UDCA), a secondary bile acid produced by intestinal bacteria as metabolic by product, has been shown effective in the non-surgical treatment of cholesterol gallston[r] ...

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Aliskiren effect on non-alcoholic steatohepatitis in metabolic syndrome

Aliskiren effect on non-alcoholic steatohepatitis in metabolic syndrome

... Non-alcoholic fat liver disease (NAFLD) consists of a disease characterized by triglyceride accumulation in hepatocytes, due to causes not related with alcohol intake, resulting in progressive liver injury and ...

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Toll-like receptor-2 deficiency enhances non-alcoholic steatohepatitis

Toll-like receptor-2 deficiency enhances non-alcoholic steatohepatitis

... Injury observed using the MCDD dietary model of ste- atohepatitis is reportedly associated with increased intes- tinal permeability and the enhanced presence of endotoxin in the portal blood supply [14,29]. Previous ...

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Salidroside alleviates oxidative stress in the liver with non- alcoholic steatohepatitis in rats

Salidroside alleviates oxidative stress in the liver with non- alcoholic steatohepatitis in rats

... The results of the current study also revealed that SDS treatment reduced the rate of upregulation of Nox2 mRNA expression in the NASH rat model. Nox2 is a membrane-bound enzyme complex. It has been shown to be involved ...

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Early liver biopsy, intraparenchymal cholestasis, and prognosis in patients with alcoholic steatohepatitis

Early liver biopsy, intraparenchymal cholestasis, and prognosis in patients with alcoholic steatohepatitis

... Histologically, ASH is defined by the presence of stea- tosis (macro- and/or microvesicular), hepatocellular injury (ballooning, apoptosis), and infiltration of the liver lobule by polynuclear neutrophils[5]. ...

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Therapeutic opportunities for alcoholic steatohepatitis and nonalcoholic steatohepatitis: exploiting similarities and differences in pathogenesis

Therapeutic opportunities for alcoholic steatohepatitis and nonalcoholic steatohepatitis: exploiting similarities and differences in pathogenesis

... In steatohepatitis, hepatocellular ballooning with cytoplasmic rarefication, inflammation accompanied by neutrophil and macrophage infil- tration, intracytoplasmic Mallory-Denk bodies (consisting of aggregated ...

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Crude triterpenoid saponins from Ilex latifolia (Da Ye Dong Qing) ameliorate lipid accumulation by inhibiting SREBP expression via activation of AMPK in a non-alcoholic fatty liver disease model

Crude triterpenoid saponins from Ilex latifolia (Da Ye Dong Qing) ameliorate lipid accumulation by inhibiting SREBP expression via activation of AMPK in a non-alcoholic fatty liver disease model

... non‑alcoholic steatohepatitis; T2DM: type 2 diabetes mellitus; UHPLC‑Q‑TOF–MS: ultra‑high performance liquid chromatography quadrupole time‑of‑flight tandem mass spectrometry; MCAO: middle cerebral artery ...

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Analysis of factors influencing glucose tolerance in Japanese patients with non-alcoholic fatty liver disease

Analysis of factors influencing glucose tolerance in Japanese patients with non-alcoholic fatty liver disease

... non-alcoholic steatohepatitis; OGTT: oral glucose tolerance test; GLP-1: glucagon like peptide-1; IRI: immunoreactive insulin; ELISA: enzyme- linked immunosorbent assay; HbA1c: glycated hemoglobin; WHO: ...

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Conclusion: The prevalence of non-alcoholic fatty liver disease in type 2 diabetes mellitus was 42.6%. It

Conclusion: The prevalence of non-alcoholic fatty liver disease in type 2 diabetes mellitus was 42.6%. It

... Non- alcoholic fatty liver disease (NAFLD) before it progresses to non-alcoholic steatohepatitis (NASH) especially in patients with risk factors like ...Non- alcoholic fatty liver disease ...

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Effect of curcumin supplementation on serum expression of select cytokines and chemokines in a female rat model of nonalcoholic steatohepatitis

Effect of curcumin supplementation on serum expression of select cytokines and chemokines in a female rat model of nonalcoholic steatohepatitis

... Objective: We recently reported that curcumin supplementation in a metabolically (i.e., Western diet [WD]) and chemically (i.e., CCl 4 ) induced female rat model of non-alcoholic steatohepatitis (NASH) was ...

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Results out of 60 patients, 28(46.66%) were males and 32(53.32%) were females. 85% of the patients

Results out of 60 patients, 28(46.66%) were males and 32(53.32%) were females. 85% of the patients

... A total of 60 patients enrolled in our study. The present study entiled “Biochemical Profile and Various Treatment Modalities of Non-alcoholic Steatohepatitis (NASH)” was undertaken at GMC, Jammu which is a ...

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Risks and Predictors of Non-Alcoholic Liver Disease Progression Using Association Rules Mining

Risks and Predictors of Non-Alcoholic Liver Disease Progression Using Association Rules Mining

... Abstract—Non-alcoholic Steatohepatitis Disease (NASH), a progression of Non-alcoholic Fatty Liver Disease (NAFLD), occurs in case of the increase of fat accumulation in the ...

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