All-trans retinoic acid (ATRA)
All trans retinoic acid (atra) inhibits telomerase expression of BeWo choriocarcinoma cell (ATCC CCL 98)
... Introduction: Choriocarcinoma is malignant cancer originating from placental trophoblast. The incidence of this cancer is estimated at 0.57-1.1 per 1000 births in the United States of America, Australia, Europe, and New ...
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All-trans-Retinoic Acid Imprints Expression of the Gut-Homing Marker α4β7 while Suppressing Lymph Node Homing of Dendritic Cells
... of all-trans-retinoic acid (ATRA) to induce gut-homing ␣47 expression on rhesus macaque plasmacytoid and myeloid DCs (pDCs and mDCs, ...controls. ATRA treatment was also ...
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Arsenic trioxide and all trans retinoic acid (ATRA) treatment for acute promyelocytic leukemia in all risk groups: study protocol for a randomized controlled trial
... of all-trans retinoic acid (ATRA) and arsenic trioxide ...However, ATRA plus chemotherapy is still the standard therapy for the high-risk ...compare ATRA-ATO with ...
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All Trans-Retinoic Acid Selectively Down-Regulates Matrix Metalloproteinase-9 (MMP-9) and Up-Regulates Tissue Inhibitor of Metalloproteinase-1 (TIMP-1) in Human Bronchoalveolar Lavage Cells
... employed all trans- retinoic acid (ATRA) a potent Vitamin A derivate be- cause this compound has been shown to suppress many activities of the monocyte lineage ...
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All trans retinoic acid modulates the retinoic acid receptor alpha in promyelocytic cells
... that all-trans retinoic acid (RA), the active metabolite of vitamin A, is an efficient alternative to chemotherapy in the treatment of acute promyelocytic leukemia ...the retinoic ...
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A fourth subtype of retinoic acid receptor-related orphan receptors is activated by oxidized all-trans retinoic acid in medaka (Oryzias latipes)
... amino acid sequence used in phylogenetic ana- lysis) was amplified by PCR and cloned into ...were trans- fected with 500 ng luciferase reporter plasmid (bmal1ap- luc or cyp26a1p-luc) and 50 ng expression ...
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Construction of asthma related competing endogenous RNA network revealed novel long non-coding RNAs and potential new drugs
... cells; ATRA: All-trans-retinoic acid; BALF: Bronchoalveolar lavage fluid; BEC: Bronchial epithelial cells; BLAST: Basic Local Alignment Search Tool; BP: Biological process; CC: Cell ...
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High-content screen in human pluripotent cells identifies miRNA-regulated pathways controlling pluripotency and differentiation
... by all-trans retinoic acid (atRA), including changes in miR expression profile [10], mor- phology, and expression of pluripotency markers ...
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Genomic amplification of MYC as double minutes in a patient with APL-like leukemia
... with all-trans retinoic acid (ATRA), which causes differentiation of the abnormal promyelocytes, combined with anthracycline based chemotherapy makes it the best curable subtype of ...
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Dual effect of oxidative stress on leukemia cancer induction and treatment
... lipoic acid; ALL: Acute lymphoblastic leukemia; AML: Acute myeloid leukemia; Ang II: Angiotensin II; ATO: Arsenic trioxide; ATRA: All-trans retinoic acid; CALLA: Common ...
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Inflammation and Nutritional Science for Programs/Policies and Interpretation of Research Evidence (INSPIRE).
... response; ATRA, all trans retinoic acid; BOND, Biomarkers of Nutrition for Development; CAMP, cathelicidin antimicrobial peptide; C/EBPe, CCAAT/enhancer binding protein e ; CD, cluster ...
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Efficacy of commercially available biological agents for the topical treatment of cervical intraepithelial neoplasia: a systematic review
... studies. All-trans retinoic acid (atRA) is an active metabolite of vitamin A under the family ...apoptosis. Retinoic acid either decreases or increases EGF- stimulated ...
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The role of stromal cancer-associated fibroblasts in pancreatic cancer
... ATRA: All- trans retinoic acid; CAF: Cancer-associated fibroblast; CA-MSCs: Cancer-associated mesenchymal stem cells; CHOP: CCAAT- enhancer-binding protein homologous protein; ECM: ...
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PML/RARa inhibits PTEN expression in hematopoietic cells by competing with PU.1 transcriptional activity
... that All-Trans Retinoic Acid (ATRA) triggers in APL cells an active chromatin status at the core regulatory region of the PTEN promoter, that allows the binding of the ...
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Regulation of human airway smooth muscle cell migration and relevance to asthma
... cognate receptor; ASM: Airway smooth muscle; ASMCs: Airway smooth muscle cells; ATRA: All-trans retinoic acid; cAMP: Cyclic adenosine monophosphate; CysLTR: Cysteinyl leukotriene recepto[r] ...
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Bayesian network meta-analysis comparing five contemporary treatment strategies for newly diagnosed acute promyelocytic leukaemia
... + all-trans retinoic acid (ATRA), realgar-indigo naturalis formula (RIF) which contains arsenic tetrasulfide + ATRA, ATRA + anthracycline- based chemotherapy (CT), ATO ...
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Pin1 inhibition exerts potent activity against acute myeloid leukemia through blocking multiple cancer-driving pathways
... Group. All-trans retinoic acid (ATRA) were purchased from Sigma, 1,25-dihydroxyvi- tamin D3 were purchased from Cayman Chemicals, and ATRA-releasing pellets were from Innovative ...
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Arsenic trioxide, a potent inhibitor of NF-κB, abrogates allergen-induced airway hyperresponsiveness and inflammation
... trioxide; ATRA, All-trans retinoic acid; BALF, Bronchoalveolar lavage fluid; ECL, Enhanced chemiluminescence; EOS, Eosinophils; ECA, EOS chemo- taxis assay; ELISA, Enzyme-linked ...
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Targeting histone methyltransferases and demethylases in clinical trials for cancer therapy
... to all-trans retinoic acid ...with ATRA-based therapies. For patients with non-APL AML, ATRA has little ...to ATRA in non-APL AML, but data strongly suggest that LSD1 may ...
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Retinoic acid uses divergent mechanisms to activate or suppress mitogenesis in rat aortic smooth muscle cells
... of all-trans retinoic acid (ATRA), as well as a number of synthetic retinoids, either alone or in the presence of a mitogenic stimulus ...cells. ATRA alone stimulates ...
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